Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     390
XP_006718908                                                           20     390
XP_005271621                                                           20     390
XP_006718907                                                           20     390
XP_006718906                                                           20     390
XP_005271619                                                           20     390
XP_005271618                                                           20     390
NP_004566                                                              17    3301
NP_006236                                                              17    4312
NP_851307                                                              17    4312
NP_795364                                                              17    4312
NP_065143                                                              16    5631
NP_872415                                                              16    5631
NP_055310                                                              16    5631
XP_005258920                                                           16    5631
XP_005258919                                                           16    5631
XP_005258917                                                           16    5631
XP_005260050                                                           16    5631
XP_005260049                                                           16    5631
XP_005271557                                                           16    5631
NP_001005468                                                           16    5631
NP_001005467                                                           16    5631
NP_001273545                                                           16    7355
NP_849148                                                              16    7355
NP_001273544                                                           16    7355
NP_060090                                                              16    7355
NP_036350                                                              16    7355
NP_919289                                                              16    7355
XP_005259952                                                           16    7355
XP_006722805                                                           16    7355
XP_006716827                                                           16    7355
XP_005251508                                                           16    7355
XP_005251507                                                           16    7355
NP_001159477                                                           15    9605
NP_001159478                                                           15    9605
NP_000932                                                              15    9605
NP_001278086                                                           15    9605
NP_001181876                                                           15    9605
NP_937887                                                              15    9605
NP_937884                                                              15    9605
NP_004944                                                              15    9605
NP_001181875                                                           15    9605
NP_937885                                                              15    9605
NP_886553                                                              15    9605
NP_689812                                                              15    9605
NP_976218                                                              15    9605
NP_001094891                                                           15    9605
XP_005245831                                                           15    9605
XP_005245830                                                           15    9605
XP_005245829                                                           15    9605
XP_005245827                                                           15    9605
XP_005245826                                                           15    9605
XP_005245825                                                           15    9605
XP_005245824                                                           15    9605
XP_005245822                                                           15    9605
XP_005245821                                                           15    9605
XP_005245820                                                           15    9605
XP_005245818                                                           15    9605
XP_006710502                                                           15    9605
XP_005245817                                                           15    9605
XP_006710501                                                           15    9605
XP_005245814                                                           15    9605
XP_006710500                                                           15    9605
XP_006710499                                                           15    9605
XP_006710498                                                           15    9605
XP_005245810                                                           15    9605
XP_006710497                                                           15    9605
NP_543015                                                              15    9605
>NP_000042
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            QQKIKYS G
Sbjct: 1578 QQKIKYSRG 1586
>XP_006718908
          Length = 1708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QQKIKYSSG 9
           QQKIKYS G
Sbjct: 230 QQKIKYSRG 238
>XP_005271621
          Length = 2708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            QQKIKYS G
Sbjct: 1230 QQKIKYSRG 1238
>XP_006718907
          Length = 3050

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            QQKIKYS G
Sbjct: 1572 QQKIKYSRG 1580
>XP_006718906
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            QQKIKYS G
Sbjct: 1578 QQKIKYSRG 1586
>XP_005271619
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            QQKIKYS G
Sbjct: 1578 QQKIKYSRG 1586
>XP_005271618
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            QQKIKYS G
Sbjct: 1578 QQKIKYSRG 1586
>NP_004566
          Length = 409

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QQKIKYSSG 9
           Q+++KYS+G
Sbjct: 400 QKRMKYSAG 408
>NP_006236
          Length = 602

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  KIKYSSG 9
          KIKYS G
Sbjct: 71 KIKYSGG 77
>NP_851307
          Length = 570

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  KIKYSSG 9
          KIKYS G
Sbjct: 71 KIKYSGG 77
>NP_795364
          Length = 307

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QKIKYSSG 9
          QK++YS G
Sbjct: 72 QKVEYSGG 79
>NP_065143
          Length = 1204

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QKIKYS 7
           QKIKYS
Sbjct: 175 QKIKYS 180
>NP_872415
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQKIKYSS 8
           + KIKYSS
Sbjct: 575 ETKIKYSS 582
>NP_055310
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQKIKY 6
           QQK+KY
Sbjct: 135 QQKVKY 140
>XP_005258920
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQKIKYSS 8
           + KIKYSS
Sbjct: 539 ETKIKYSS 546
>XP_005258919
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQKIKYSS 8
           + KIKYSS
Sbjct: 539 ETKIKYSS 546
>XP_005258917
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQKIKYSS 8
           + KIKYSS
Sbjct: 575 ETKIKYSS 582
>XP_005260050
          Length = 1227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QKIKYS 7
           QKIKYS
Sbjct: 175 QKIKYS 180
>XP_005260049
          Length = 1242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QKIKYS 7
           QKIKYS
Sbjct: 175 QKIKYS 180
>XP_005271557
          Length = 313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IKYSSG 9
           IKYSSG
Sbjct: 260 IKYSSG 265
>NP_001005468
          Length = 313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IKYSSG 9
           IKYSSG
Sbjct: 260 IKYSSG 265
>NP_001005467
          Length = 313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IKYSSG 9
           IKYSSG
Sbjct: 260 IKYSSG 265
>NP_001273545
          Length = 955

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QKIKYSSG 9
           Q+IKY  G
Sbjct: 269 QRIKYEEG 276
>NP_849148
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QKIKYSSG 9
           Q+IKY  G
Sbjct: 234 QRIKYEEG 241
>NP_001273544
          Length = 955

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QKIKYSSG 9
           Q+IKY  G
Sbjct: 269 QRIKYEEG 276
>NP_060090
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QQKIKYSSG 9
           QQK  Y SG
Sbjct: 744 QQKPSYGSG 752
>NP_036350
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QQKIKYSSG 9
           QQK  Y SG
Sbjct: 740 QQKPSYGSG 748
>NP_919289
          Length = 1368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQKIKY 6
           QQK+KY
Sbjct: 778 QQKLKY 783
>XP_005259952
          Length = 633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QQKIKYSSG 9
           QQK  Y SG
Sbjct: 479 QQKPSYGSG 487
>XP_006722805
          Length = 855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QQKIKYSSG 9
           QQK  Y SG
Sbjct: 744 QQKPSYGSG 752
>XP_006716827
          Length = 910

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQKIKY 6
           QQK+KY
Sbjct: 320 QQKLKY 325
>XP_005251508
          Length = 1007

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQKIKY 6
           QQK+KY
Sbjct: 417 QQKLKY 422
>XP_005251507
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQKIKY 6
           QQK+KY
Sbjct: 489 QQKLKY 494
>NP_001159477
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>NP_001159478
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>NP_000932
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KIKYSSG 9
           KI+Y SG
Sbjct: 314 KIRYESG 320
>NP_001278086
          Length = 1559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1379 EQKVEYTLG 1387
>NP_001181876
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1426 EQKVEYTLG 1434
>NP_937887
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1332 EQKVEYTLG 1340
>NP_937884
          Length = 1599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1419 EQKVEYTLG 1427
>NP_004944
          Length = 1404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1224 EQKVEYTLG 1232
>NP_001181875
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1426 EQKVEYTLG 1434
>NP_937885
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1255 EQKVEYTLG 1263
>NP_886553
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    QQKIKYSSG 9
            +QK++Y+ G
Sbjct: 1420 EQKVEYTLG 1428
>NP_689812
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQKIKYS 7
           ++KIKYS
Sbjct: 548 ERKIKYS 554
>NP_976218
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>NP_001094891
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQKIKYSS 8
           +QKI+YS+
Sbjct: 916 KQKIEYSA 923
>XP_005245831
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245830
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245829
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245827
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245826
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245825
          Length = 821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245824
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245822
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245821
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245820
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245818
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_006710502
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245817
          Length = 881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_006710501
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245814
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_006710500
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_006710499
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_006710498
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_005245810
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>XP_006710497
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QQKIKYSSG 9
          +QK+K S+G
Sbjct: 50 EQKLKASNG 58
>NP_543015
          Length = 153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QKIKYSSG 9
          Q+I Y+SG
Sbjct: 62 QRIDYASG 69
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.117    0.294 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 611,207
Number of extensions: 1132
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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