Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              18    1935
NP_005913                                                              18    1935
XP_005267046                                                           18    1935
XP_005267045                                                           18    1935
NP_055496                                                              16    7355
XP_005259500                                                           16    7355
NP_001245340                                                           15    9605
NP_001245342                                                           15    9605
NP_443176                                                              15    9605
NP_001245341                                                           15    9605
NP_006651                                                              15    9605
NP_001010905                                                           15    9605
NP_001245343                                                           15    9605
XP_005255139                                                           15    9605
XP_006721078                                                           15    9605
XP_005255138                                                           15    9605
XP_006721077                                                           15    9605
XP_005255137                                                           15    9605
>NP_006715
          Length = 1558

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QMGLIKLIL 9
           QMGL KLIL
Sbjct: 536 QMGLRKLIL 544
>NP_005913
          Length = 1608

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QMGLIKLIL 9
           QMGL KLIL
Sbjct: 536 QMGLRKLIL 544
>XP_005267046
          Length = 1554

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QMGLIKLIL 9
           QMGL KLIL
Sbjct: 536 QMGLRKLIL 544
>XP_005267045
          Length = 1604

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QMGLIKLIL 9
           QMGL KLIL
Sbjct: 536 QMGLRKLIL 544
>NP_055496
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QMGLIKLIL 9
           Q+ L+KL+L
Sbjct: 796 QLALLKLVL 804
>XP_005259500
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QMGLIKLIL 9
           Q+ L+KL+L
Sbjct: 796 QLALLKLVL 804
>NP_001245340
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 455 LGLVRLVL 462
>NP_001245342
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 426 LGLVRLVL 433
>NP_443176
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 490 LGLVRLVL 497
>NP_001245341
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 420 LGLVRLVL 427
>NP_006651
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QMGLIKLI 8
           Q GL+KL+
Sbjct: 381 QQGLLKLL 388
>NP_001010905
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMGLIKLIL 9
          +MG+ K+IL
Sbjct: 60 RMGMYKIIL 68
>NP_001245343
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 334 LGLVRLVL 341
>XP_005255139
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 329 LGLVRLVL 336
>XP_006721078
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 391 LGLVRLVL 398
>XP_005255138
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 398 LGLVRLVL 405
>XP_006721077
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 470 LGLVRLVL 477
>XP_005255137
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MGLIKLIL 9
           +GL++L+L
Sbjct: 490 LGLVRLVL 497
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.162    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 411,105
Number of extensions: 629
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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