Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055973                                                              17    3301
NP_001243805                                                           17    3301
NP_694856                                                              17    3301
NP_001243806                                                           17    3301
XP_006716811                                                           17    3301
XP_006716810                                                           17    3301
XP_005251476                                                           17    3301
XP_005251475                                                           17    3301
XP_005251473                                                           17    3301
XP_005251474                                                           17    3301
XP_005251472                                                           17    3301
XP_005251471                                                           17    3301
XP_005251470                                                           17    3301
XP_006716809                                                           17    3301
XP_006716808                                                           17    3301
XP_006716807                                                           17    3301
XP_006716806                                                           17    3301
XP_005251468                                                           17    3301
XP_005251467                                                           17    3301
NP_000929                                                              17    4312
NP_071351                                                              16    5631
NP_001188412                                                           16    7355
NP_001419                                                              16    7355
NP_079410                                                              16    7355
XP_005256233                                                           16    7355
XP_005256232                                                           16    7355
XP_005256231                                                           16    7355
XP_005256229                                                           16    7355
XP_005256228                                                           16    7355
XP_005256227                                                           16    7355
XP_006721346                                                           16    7355
XP_005256226                                                           16    7355
XP_006721345                                                           16    7355
XP_006721344                                                           16    7355
XP_006721343                                                           16    7355
XP_005256225                                                           16    7355
XP_006720617                                                           16    7355
XP_006710496                                                           16    7355
NP_002408                                                              15    9605
NP_001139438                                                           15    9605
NP_005214                                                              15    9605
NP_510882                                                              15    9605
NP_114146                                                              15    9605
NP_001019552                                                           15    9605
NP_001019551                                                           15    9605
NP_919274                                                              15    9605
NP_055871                                                              15    9605
XP_005255205                                                           15    9605
XP_006720916                                                           15    9605
XP_006720915                                                           15    9605
XP_006717927                                                           15    9605
XP_005252603                                                           15    9605
XP_006716471                                                           15    9605
XP_005273714                                                           15    9605
XP_005247838                                                           15    9605
NP_079044                                                              15    9605
>NP_055973
          Length = 1352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>NP_001243805
          Length = 1352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>NP_694856
          Length = 1194

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>NP_001243806
          Length = 1352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_006716811
          Length = 1120

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_006716810
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>XP_005251476
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>XP_005251475
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>XP_005251473
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>XP_005251474
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>XP_005251472
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>XP_005251471
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 733 QKTSLGKI 740
>XP_005251470
          Length = 1284

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_006716809
          Length = 1334

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_006716808
          Length = 1346

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_006716807
          Length = 1352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_006716806
          Length = 1364

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_005251468
          Length = 1364

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>XP_005251467
          Length = 1364

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QKTAIGKV 8
           QKT++GK+
Sbjct: 891 QKTSLGKI 898
>NP_000929
          Length = 1174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QKTAIGKV 8
           QKT IGK+
Sbjct: 145 QKTFIGKI 152
>NP_071351
          Length = 2752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QKTAIGKVL 9
            +KT +GKV+
Sbjct: 2253 RKTVLGKVI 2261
>NP_001188412
          Length = 341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KTAIGK 7
           KTAIGK
Sbjct: 135 KTAIGK 140
>NP_001419
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KTAIGK 7
           KTAIGK
Sbjct: 228 KTAIGK 233
>NP_079410
          Length = 2881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_005256233
          Length = 2391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QKTAIGKVL 9
          +KT IGK++
Sbjct: 83 EKTKIGKLI 91
>XP_005256232
          Length = 2424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 116 EKTKIGKLI 124
>XP_005256231
          Length = 2573

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_005256229
          Length = 2881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_005256228
          Length = 2882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_005256227
          Length = 2897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_006721346
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_005256226
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_006721345
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_006721344
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_006721343
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_005256225
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           +KT IGK++
Sbjct: 590 EKTKIGKLI 598
>XP_006720617
          Length = 212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QKTAIGKVL 9
           QKT+ GK+L
Sbjct: 197 QKTSEGKML 205
>XP_006710496
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KTAIGK 7
           KTAIGK
Sbjct: 228 KTAIGK 233
>NP_002408
          Length = 3256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KTAIGKV 8
            KT++GKV
Sbjct: 1634 KTSLGKV 1640
>NP_001139438
          Length = 2896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KTAIGKV 8
            KT++GKV
Sbjct: 1274 KTSLGKV 1280
>NP_005214
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TAIGKVL 9
          TA+GK+L
Sbjct: 68 TAVGKLL 74
>NP_510882
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAIGKVL 9
           TA+GK+L
Sbjct: 175 TAVGKLL 181
>NP_114146
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAIGKVL 9
           TA+GK+L
Sbjct: 132 TAVGKLL 138
>NP_001019552
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAIGKVL 9
           TA+GK+L
Sbjct: 132 TAVGKLL 138
>NP_001019551
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAIGKVL 9
           TA+GK+L
Sbjct: 132 TAVGKLL 138
>NP_919274
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAIGKVL 9
           TA+GK+L
Sbjct: 353 TAVGKLL 359
>NP_055871
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKTAIGK 7
           +KTA+GK
Sbjct: 263 KKTALGK 269
>XP_005255205
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TAIGKVL 9
          TA+GK+L
Sbjct: 68 TAVGKLL 74
>XP_006720916
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TAIGKVL 9
          TA+GK+L
Sbjct: 68 TAVGKLL 74
>XP_006720915
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TAIGKVL 9
          TA+GK+L
Sbjct: 68 TAVGKLL 74
>XP_006717927
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KTAIGKV 8
           KT++GKV
Sbjct: 784 KTSLGKV 790
>XP_005252603
          Length = 1457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QKTAIGK 7
            +KTA+GK
Sbjct: 1440 KKTALGK 1446
>XP_006716471
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAIGKVL 9
           TA+GK+L
Sbjct: 132 TAVGKLL 138
>XP_005273714
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAIGKVL 9
           TA+GK+L
Sbjct: 132 TAVGKLL 138
>XP_005247838
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTAIGKVL 9
           K A+GK+L
Sbjct: 535 KRALGKIL 542
>NP_079044
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTAIGKVL 9
           K A+GK+L
Sbjct: 534 KRALGKIL 541
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.131    0.326 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,442
Number of extensions: 668
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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