Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_620706                                                              18    1935
NP_003066                                                              18    1935
NP_001123892                                                           18    1935
NP_003065                                                              18    1935
NP_006452                                                              18    1935
NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006726410                                                           18    1935
XP_005269161                                                           18    1935
XP_005269160                                                           18    1935
XP_005269159                                                           18    1935
XP_005269158                                                           18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
XP_006711164                                                           18    1935
XP_006710143                                                           18    1935
XP_006710142                                                           18    1935
XP_006710141                                                           18    1935
NP_055196                                                              16    5631
NP_001035197                                                           16    5631
XP_005267591                                                           16    5631
XP_005267590                                                           16    5631
XP_005267589                                                           16    5631
XP_005267588                                                           16    5631
XP_006720179                                                           16    5631
NP_001164269                                                           15    9605
>NP_620706
          Length = 1130

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 635 QETLLLLEA 643
>NP_003066
          Length = 1214

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 604 QETLLLLEA 612
>NP_001123892
          Length = 1152

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 635 QETLLLLEA 643
>NP_003065
          Length = 1105

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 626 QETLLLLEA 634
>NP_006452
          Length = 1193

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLLS A
Sbjct: 898 QETLLLSTA 906
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1187 QEKLLLSEA 1195
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1231 QEKLLLSEA 1239
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1231 QEKLLLSEA 1239
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1034 QEKLLLSEA 1042
>XP_005269161
          Length = 1151

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 634 QETLLLLEA 642
>XP_005269160
          Length = 1213

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 603 QETLLLLEA 611
>XP_005269159
          Length = 1244

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 634 QETLLLLEA 642
>XP_005269158
          Length = 1245

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QETLLL EA
Sbjct: 635 QETLLLLEA 643
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1187 QEKLLLSEA 1195
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QE LLLSEA
Sbjct: 238 QEKLLLSEA 246
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1187 QEKLLLSEA 1195
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1297 QEKLLLSEA 1305
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1231 QEKLLLSEA 1239
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1231 QEKLLLSEA 1239
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1234 QEKLLLSEA 1242
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1284 QEKLLLSEA 1292
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1297 QEKLLLSEA 1305
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1297 QEKLLLSEA 1305
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1394 QEKLLLSEA 1402
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QETLLLSEA 9
            QE LLLSEA
Sbjct: 1034 QEKLLLSEA 1042
>XP_006710143
          Length = 562

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QETLLLSEA 9
          QE LLLSEA
Sbjct: 73 QEKLLLSEA 81
>XP_006710142
          Length = 671

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QE LLLSEA
Sbjct: 183 QEKLLLSEA 191
>XP_006710141
          Length = 672

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QE LLLSEA
Sbjct: 183 QEKLLLSEA 191
>NP_055196
          Length = 1429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QET++ SEA
Sbjct: 473 QETIVASEA 481
>NP_001035197
          Length = 1453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QET++ SEA
Sbjct: 473 QETIVASEA 481
>XP_005267591
          Length = 1275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QET++ SEA
Sbjct: 473 QETIVASEA 481
>XP_005267590
          Length = 1394

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QET++ SEA
Sbjct: 473 QETIVASEA 481
>XP_005267589
          Length = 1418

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QET++ SEA
Sbjct: 473 QETIVASEA 481
>XP_005267588
          Length = 1453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QET++ SEA
Sbjct: 473 QETIVASEA 481
>XP_006720179
          Length = 1453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QETLLLSEA 9
           QET++ SEA
Sbjct: 473 QETIVASEA 481
>NP_001164269
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QETLLLSE 8
           +ETLLL E
Sbjct: 549 EETLLLHE 556
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.117    0.255 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 345,340
Number of extensions: 406
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package