Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     299
XP_006718908                                                           20     299
XP_005271621                                                           20     299
XP_006718907                                                           20     299
XP_006718906                                                           20     299
XP_005271619                                                           20     299
XP_005271618                                                           20     299
NP_003176                                                              16    5631
NP_001175                                                              16    7355
NP_057417                                                              16    7355
NP_001164056                                                           16    7355
NP_694566                                                              16    7355
XP_005255284                                                           16    7355
XP_005255283                                                           16    7355
XP_006720936                                                           16    7355
XP_006720935                                                           16    7355
XP_005255282                                                           16    7355
XP_006719000                                                           16    7355
NP_612351                                                              16    7355
NP_001073876                                                           15    9605
XP_006718823                                                           15    9605
NP_839943                                                              15    9605



>NP_000042
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QEPMMALRT 9
            QEP+MALRT
Sbjct: 2220 QEPIMALRT 2228





>XP_006718908
          Length = 1708

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QEPMMALRT 9
           QEP+MALRT
Sbjct: 872 QEPIMALRT 880





>XP_005271621
          Length = 2708

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QEPMMALRT 9
            QEP+MALRT
Sbjct: 1872 QEPIMALRT 1880





>XP_006718907
          Length = 3050

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QEPMMALRT 9
            QEP+MALRT
Sbjct: 2214 QEPIMALRT 2222





>XP_006718906
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QEPMMALRT 9
            QEP+MALRT
Sbjct: 2220 QEPIMALRT 2228





>XP_005271619
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QEPMMALRT 9
            QEP+MALRT
Sbjct: 2220 QEPIMALRT 2228





>XP_005271618
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QEPMMALRT 9
            QEP+MALRT
Sbjct: 2220 QEPIMALRT 2228





>NP_003176
          Length = 1085

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QEPMMALR 8
           Q PM+ALR
Sbjct: 762 QTPMVALR 769





>NP_001175
          Length = 2644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QEPMMALR 8
            +EP++ALR
Sbjct: 1897 KEPILALR 1904





>NP_057417
          Length = 2752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PMMALRT 9
            P+M+LRT
Sbjct: 2216 PLMSLRT 2222





>NP_001164056
          Length = 1447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QEPMMALRT 9
            ++P M+LRT
Sbjct: 1436 EDPPMSLRT 1444





>NP_694566
          Length = 1458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QEPMMALRT 9
            ++P M+LRT
Sbjct: 1447 EDPPMSLRT 1455





>XP_005255284
          Length = 2581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PMMALRT 9
            P+M+LRT
Sbjct: 2216 PLMSLRT 2222





>XP_005255283
          Length = 2751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PMMALRT 9
            P+M+LRT
Sbjct: 2216 PLMSLRT 2222





>XP_006720936
          Length = 2751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PMMALRT 9
            P+M+LRT
Sbjct: 2215 PLMSLRT 2221





>XP_006720935
          Length = 2752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PMMALRT 9
            P+M+LRT
Sbjct: 2216 PLMSLRT 2222





>XP_005255282
          Length = 2752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PMMALRT 9
            P+M+LRT
Sbjct: 2216 PLMSLRT 2222





>XP_006719000
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QEPMMALRT 9
           Q+P M LRT
Sbjct: 154 QDPGMRLRT 162





>NP_612351
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QEPMMALRT 9
           Q+P M LRT
Sbjct: 154 QDPGMRLRT 162





>NP_001073876
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QEPMMALRT 9
           Q+P + LRT
Sbjct: 180 QDPRLLLRT 188





>XP_006718823
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QEPMMALRT 9
           Q+P + LRT
Sbjct: 538 QDPRLLLRT 546





>NP_839943
          Length = 1631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QEPMMALR 8
           Q+P +ALR
Sbjct: 317 QDPALALR 324





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.123    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 553,862
Number of extensions: 491
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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