Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_361014                                                              19     869
NP_001243998                                                           19     869
NP_008941                                                              17    3301
NP_001278405                                                           17    3301
XP_006725362                                                           17    3301
XP_006721713                                                           17    3301
NP_054888                                                              16    5631
NP_694972                                                              16    7355
NP_976241                                                              16    7355
NP_998754                                                              16    7355
NP_919223                                                              16    7355
NP_037491                                                              16    7355
NP_071325                                                              16    7355
NP_998778                                                              16    7355
NP_001713                                                              16    7355
NP_001231681                                                           16    7355
XP_005259263                                                           16    7355
XP_006716835                                                           16    7355
XP_006716834                                                           16    7355
XP_006716833                                                           16    7355
XP_006716832                                                           16    7355
XP_006713920                                                           16    7355
XP_006713919                                                           16    7355
XP_005246837                                                           16    7355
XP_005246836                                                           16    7355
XP_006712758                                                           16    7355
XP_005246834                                                           16    7355
XP_006712428                                                           16    7355
XP_005246439                                                           16    7355
XP_005246438                                                           16    7355
XP_005246437                                                           16    7355
NP_849150                                                              16    7355
NP_002308                                                              15    9605
NP_001005474                                                           15    9605
NP_113607                                                              15    9605
NP_001004334                                                           15    9605
NP_001186862                                                           15    9605
NP_055269                                                              15    9605
NP_689985                                                              15    9605
NP_443078                                                              15    9605
NP_079303                                                              15    9605
NP_116036                                                              15    9605
NP_005180                                                              15    9605
XP_005259334                                                           15    9605
XP_005259333                                                           15    9605
XP_005268826                                                           15    9605
XP_006719386                                                           15    9605
XP_005268825                                                           15    9605
XP_005268823                                                           15    9605
XP_005268824                                                           15    9605
NP_001956                                                              15    9605
>NP_361014
          Length = 707

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QELLSVGSQ 9
          QELLSVGS+
Sbjct: 3  QELLSVGSK 11
>NP_001243998
          Length = 176

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QELLSVGSQ 9
          QELLSVGS+
Sbjct: 3  QELLSVGSK 11
>NP_008941
          Length = 599

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QELL VGS+
Sbjct: 388 QELLFVGSE 396
>NP_001278405
          Length = 491

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QELL VGS+
Sbjct: 280 QELLFVGSE 288
>XP_006725362
          Length = 413

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QELL VGS+
Sbjct: 202 QELLFVGSE 210
>XP_006721713
          Length = 413

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QELL VGS+
Sbjct: 202 QELLFVGSE 210
>NP_054888
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QELL+VG +
Sbjct: 218 QELLNVGDK 226
>NP_694972
          Length = 1330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELLS+G
Sbjct: 107 QELLSMG 113
>NP_976241
          Length = 644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QELLSVGS 8
           QEL S+GS
Sbjct: 98  QELSSIGS 105
>NP_998754
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QELLSVGS 8
           QEL S+GS
Sbjct: 98  QELSSIGS 105
>NP_919223
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QELLSVGSQ 9
           QE+ S GSQ
Sbjct: 205 QEMQSAGSQ 213
>NP_037491
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QELLSVGSQ 9
          + LLSVG+Q
Sbjct: 64 RNLLSVGNQ 72
>NP_071325
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELL+VG
Sbjct: 375 QELLAVG 381
>NP_998778
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELL+VG
Sbjct: 375 QELLAVG 381
>NP_001713
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QEL+SVG
Sbjct: 358 QELVSVG 364
>NP_001231681
          Length = 1010

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELLS+G
Sbjct: 784 QELLSMG 790
>XP_005259263
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QELLSVGSQ 9
          + LLSVG+Q
Sbjct: 64 RNLLSVGNQ 72
>XP_006716835
          Length = 1048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELLS+G
Sbjct: 757 QELLSMG 763
>XP_006716834
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELLS+G
Sbjct: 785 QELLSMG 791
>XP_006716833
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELLS+G
Sbjct: 803 QELLSMG 809
>XP_006716832
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELLS+G
Sbjct: 803 QELLSMG 809
>XP_006713920
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELL+VG
Sbjct: 375 QELLAVG 381
>XP_006713919
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QELLSVG 7
           QELL+VG
Sbjct: 375 QELLAVG 381
>XP_005246837
          Length = 1277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QELLSVGS 8
           QEL S+GS
Sbjct: 98  QELSSIGS 105
>XP_005246836
          Length = 1302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QELLSVGS 8
           QEL S+GS
Sbjct: 98  QELSSIGS 105
>XP_006712758
          Length = 1302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QELLSVGS 8
           QEL S+GS
Sbjct: 98  QELSSIGS 105
>XP_005246834
          Length = 1302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QELLSVGS 8
           QEL S+GS
Sbjct: 98  QELSSIGS 105
>XP_006712428
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QELLSVGSQ 9
           QE+ S GSQ
Sbjct: 205 QEMQSAGSQ 213
>XP_005246439
          Length = 341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QELLSVGSQ 9
           QE+ S GSQ
Sbjct: 205 QEMQSAGSQ 213
>XP_005246438
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QELLSVGSQ 9
           QE+ S GSQ
Sbjct: 183 QEMQSAGSQ 191
>XP_005246437
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QELLSVGSQ 9
           QE+ S GSQ
Sbjct: 205 QEMQSAGSQ 213
>NP_849150
          Length = 1445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ELLSVGSQ 9
            ++LS+GSQ
Sbjct: 1018 QVLSIGSQ 1025
>NP_002308
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLSVGSQ 9
          LLS+GSQ
Sbjct: 57 LLSLGSQ 63
>NP_001005474
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QELLSVGSQ 9
           Q+L+++G+Q
Sbjct: 397 QDLVNIGAQ 405
>NP_113607
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QELLSVGSQ 9
           Q+L+++G+Q
Sbjct: 497 QDLVNIGAQ 505
>NP_001004334
          Length = 2367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QELLSVGS 8
            QE+LS+G+
Sbjct: 1490 QEMLSLGT 1497
>NP_001186862
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QELLSVGSQ 9
          +E+L VGS+
Sbjct: 55 KEILQVGSE 63
>NP_055269
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           +E+L VGS+
Sbjct: 114 KEILQVGSE 122
>NP_689985
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QEL ++GSQ
Sbjct: 471 QELEALGSQ 479
>NP_443078
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QELLSVGSQ 9
           QEL  +GSQ
Sbjct: 364 QELSQLGSQ 372
>NP_079303
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLSVGSQ 9
           LLSVG+Q
Sbjct: 98  LLSVGNQ 104
>NP_116036
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QELLSVGSQ 9
          +EL SVG Q
Sbjct: 2  EELSSVGEQ 10
>NP_005180
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QELLSVGSQ 9
          +EL SVG Q
Sbjct: 2  EELSSVGEQ 10
>XP_005259334
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLSVGSQ 9
          LLSVG+Q
Sbjct: 8  LLSVGNQ 14
>XP_005259333
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLSVGSQ 9
           LLSVG+Q
Sbjct: 98  LLSVGNQ 104
>XP_005268826
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QEL ++GSQ
Sbjct: 406 QELEALGSQ 414
>XP_006719386
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QEL ++GSQ
Sbjct: 471 QELEALGSQ 479
>XP_005268825
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QEL ++GSQ
Sbjct: 471 QELEALGSQ 479
>XP_005268823
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QEL ++GSQ
Sbjct: 471 QELEALGSQ 479
>XP_005268824
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QELLSVGSQ 9
           QEL ++GSQ
Sbjct: 471 QELEALGSQ 479
>NP_001956
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ELLSVGS 8
           ELLSVG+
Sbjct: 312 ELLSVGA 318
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.120    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 531,066
Number of extensions: 1047
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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