Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     509
XP_006718908                                                           20     509
XP_005271621                                                           20     509
XP_006718907                                                           20     509
XP_006718906                                                           20     509
XP_005271619                                                           20     509
XP_005271618                                                           20     509
NP_071349                                                              17    4312
NP_001193849                                                           17    4312
XP_005257625                                                           17    4312
XP_005257624                                                           17    4312
NP_114409                                                              16    5631
NP_149100                                                              16    5631
XP_005264686                                                           16    5631
NP_036246                                                              16    7355
NP_004790                                                              16    7355
NP_015563                                                              16    7355
NP_055144                                                              16    7355
NP_001271165                                                           15    9605
NP_001091738                                                           15    9605
NP_002303                                                              15    9605
NP_996820                                                              15    9605
NP_001098721                                                           15    9605
NP_055548                                                              15    9605
NP_694997                                                              15    9605
NP_001264671                                                           15    9605
NP_063938                                                              15    9605
XP_006723647                                                           15    9605
XP_006723646                                                           15    9605
XP_005260799                                                           15    9605
XP_006723645                                                           15    9605
XP_006723644                                                           15    9605
XP_006720015                                                           15    9605
XP_005254115                                                           15    9605
XP_005254113                                                           15    9605
XP_005254114                                                           15    9605
XP_006720014                                                           15    9605
XP_006720013                                                           15    9605
XP_005273935                                                           15    9605
XP_005273934                                                           15    9605
XP_005273933                                                           15    9605
XP_006718554                                                           15    9605
XP_006718553                                                           15    9605
XP_006718552                                                           15    9605
XP_005248689                                                           15    9605
XP_005264490                                                           15    9605
NP_001092877                                                           15    9605
>NP_000042
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            QDGIMVKL
Sbjct: 1640 QDGIMVKL 1647
>XP_006718908
          Length = 1708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QDGIMVKL 8
           QDGIMVKL
Sbjct: 292 QDGIMVKL 299
>XP_005271621
          Length = 2708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            QDGIMVKL
Sbjct: 1292 QDGIMVKL 1299
>XP_006718907
          Length = 3050

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            QDGIMVKL
Sbjct: 1634 QDGIMVKL 1641
>XP_006718906
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            QDGIMVKL
Sbjct: 1640 QDGIMVKL 1647
>XP_005271619
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            QDGIMVKL
Sbjct: 1640 QDGIMVKL 1647
>XP_005271618
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            QDGIMVKL
Sbjct: 1640 QDGIMVKL 1647
>NP_071349
          Length = 1292

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GIMVK F
Sbjct: 971 EGIMVKTF 978
>NP_001193849
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QDGIMVKLF 9
           +DG+ +KLF
Sbjct: 203 EDGLTLKLF 211
>XP_005257625
          Length = 1268

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GIMVK F
Sbjct: 947 EGIMVKTF 954
>XP_005257624
          Length = 1293

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GIMVK F
Sbjct: 972 EGIMVKTF 979
>NP_114409
          Length = 467

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QDGIMVKL 8
           Q+GIMV+L
Sbjct: 438 QNGIMVEL 445
>NP_149100
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIMVKLF 9
           G+MVKL+
Sbjct: 693 GVMVKLY 699
>XP_005264686
          Length = 703

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIMVKLF 9
           G+MVKL+
Sbjct: 613 GVMVKLY 619
>NP_036246
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QDGIMVKL 8
           +DG MVKL
Sbjct: 98  EDGEMVKL 105
>NP_004790
          Length = 1425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            +DG+MV++
Sbjct: 1223 EDGVMVQI 1230
>NP_015563
          Length = 1366

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            +DG+MV++
Sbjct: 1164 EDGVMVQI 1171
>NP_055144
          Length = 1401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   GIMVKLF 9
           G+++KLF
Sbjct: 503 GVLIKLF 509
>NP_001271165
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            +DG+MV++
Sbjct: 1341 EDGLMVQI 1348
>NP_001091738
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>NP_002303
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>NP_996820
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>NP_001098721
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            +DG+MV++
Sbjct: 1341 EDGLMVQI 1348
>NP_055548
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            +DG+MV++
Sbjct: 1341 EDGLMVQI 1348
>NP_694997
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GI VK+F
Sbjct: 212 EGISVKMF 219
>NP_001264671
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DGIMVKLF 9
           DG+ VK F
Sbjct: 409 DGLSVKFF 416
>NP_063938
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DGIMVKLF 9
           DG+ VK F
Sbjct: 484 DGLSVKFF 491
>XP_006723647
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QDGIMVKLF 9
           Q GI+ K+F
Sbjct: 92  QSGIVTKVF 100
>XP_006723646
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QDGIMVKLF 9
           Q GI+ K+F
Sbjct: 92  QSGIVTKVF 100
>XP_005260799
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QDGIMVKLF 9
           Q GI+ K+F
Sbjct: 92  QSGIVTKVF 100
>XP_006723645
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QDGIMVKLF 9
           Q GI+ K+F
Sbjct: 92  QSGIVTKVF 100
>XP_006723644
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QDGIMVKLF 9
           Q GI+ K+F
Sbjct: 116 QSGIVTKVF 124
>XP_006720015
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>XP_005254115
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>XP_005254113
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>XP_005254114
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>XP_006720014
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>XP_006720013
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QDGIMVK 7
           ++GIMVK
Sbjct: 426 EEGIMVK 432
>XP_005273935
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GI VK+F
Sbjct: 213 EGISVKMF 220
>XP_005273934
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GI VK+F
Sbjct: 212 EGISVKMF 219
>XP_005273933
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GI VK+F
Sbjct: 213 EGISVKMF 220
>XP_006718554
          Length = 946

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GI VK+F
Sbjct: 262 EGISVKMF 269
>XP_006718553
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GI VK+F
Sbjct: 263 EGISVKMF 270
>XP_006718552
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DGIMVKLF 9
           +GI VK+F
Sbjct: 263 EGISVKMF 270
>XP_005248689
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QDGIMVKL 8
            +DG+MV++
Sbjct: 1341 EDGLMVQI 1348
>XP_005264490
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DGIMVKLF 9
           DG+ VK F
Sbjct: 426 DGLSVKFF 433
>NP_001092877
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QDGIMVKLF 9
           Q GI+ K+F
Sbjct: 92  QSGIVTKVF 100
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.155    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 425,929
Number of extensions: 540
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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