Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008877                                                              18    1135
XP_005274250                                                           18    1135
XP_006718734                                                           18    1135
XP_006718733                                                           18    1135
XP_005274249                                                           18    1135
XP_006718732                                                           18    1135
NP_065988                                                              17    2528
NP_060444                                                              17    2528
NP_110430                                                              17    2528
NP_899236                                                              17    2528
NP_056363                                                              17    2528
NP_001138241                                                           17    2528
NP_001138242                                                           17    2528
NP_001177195                                                           17    2528
NP_001177196                                                           17    2528
XP_005267986                                                           17    2528
XP_006715232                                                           17    2528
XP_005249382                                                           17    2528
XP_005249381                                                           17    2528
XP_005249380                                                           17    2528
XP_005249379                                                           17    2528
XP_005249377                                                           17    2528
XP_005249376                                                           17    2528
XP_005249375                                                           17    2528
XP_005249374                                                           17    2528
XP_005249373                                                           17    2528
XP_005249372                                                           17    2528
XP_005249371                                                           17    2528
XP_005249370                                                           17    2528
XP_005249369                                                           17    2528
XP_005249368                                                           17    2528
XP_005249367                                                           17    2528
XP_005246139                                                           17    2528
NP_775901                                                              17    3301
XP_006722498                                                           17    3301
XP_006722497                                                           17    3301
NP_001050                                                              16    5631
NP_443188                                                              16    5631
XP_006721080                                                           16    5631
XP_006721079                                                           16    5631
XP_005255141                                                           16    5631
NP_004527                                                              16    7355
NP_075043                                                              16    7355
XP_006725522                                                           16    7355
XP_006725521                                                           16    7355
XP_006725518                                                           16    7355
XP_006725517                                                           16    7355
XP_006725516                                                           16    7355
XP_005276859                                                           16    7355
XP_005276858                                                           16    7355
XP_006726284                                                           16    7355
XP_006726283                                                           16    7355
XP_006726282                                                           16    7355
XP_005248581                                                           16    7355
XP_006714693                                                           16    7355
XP_006714691                                                           16    7355
XP_006714690                                                           16    7355
XP_006714689                                                           16    7355
NP_036342                                                              15    9605
NP_001093149                                                           15    9605
NP_777586                                                              15    9605
NP_001185599                                                           15    9605
NP_001018091                                                           15    9605
NP_001012999                                                           15    9605
NP_065396                                                              15    9605
XP_006725855                                                           15    9605
XP_006725728                                                           15    9605
XP_006725720                                                           15    9605
XP_006725502                                                           15    9605
XP_006725494                                                           15    9605
XP_006725485                                                           15    9605
XP_006725705                                                           15    9605
XP_005251870                                                           15    9605
>NP_008877
          Length = 2390

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCMFLRTKL 9
            QC+FLR +L
Sbjct: 1139 QCLFLRQRL 1147
>XP_005274250
          Length = 2390

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCMFLRTKL 9
            QC+FLR +L
Sbjct: 1139 QCLFLRQRL 1147
>XP_006718734
          Length = 2390

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCMFLRTKL 9
            QC+FLR +L
Sbjct: 1139 QCLFLRQRL 1147
>XP_006718733
          Length = 2390

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCMFLRTKL 9
            QC+FLR +L
Sbjct: 1139 QCLFLRQRL 1147
>XP_005274249
          Length = 2390

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCMFLRTKL 9
            QC+FLR +L
Sbjct: 1139 QCLFLRQRL 1147
>XP_006718732
          Length = 2397

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCMFLRTKL 9
            QC+FLR +L
Sbjct: 1146 QCLFLRQRL 1154
>NP_065988
          Length = 2048

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +CMF RT+
Sbjct: 417 ECMFARTR 424
>NP_060444
          Length = 588

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QCMFLRTKL 9
           +C+ LRTKL
Sbjct: 144 ECLDLRTKL 152
>NP_110430
          Length = 607

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QCMFLRTKL 9
           +C+ LRTKL
Sbjct: 144 ECLDLRTKL 152
>NP_899236
          Length = 5497

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 3076 KCSFLETKL 3084
>NP_056363
          Length = 5171

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 2750 KCSFLETKL 2758
>NP_001138241
          Length = 5675

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 3254 KCSFLETKL 3262
>NP_001138242
          Length = 5537

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 3116 KCSFLETKL 3124
>NP_001177195
          Length = 523

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QCMFLRTKL 9
          +C+ LRTKL
Sbjct: 60 ECLDLRTKL 68
>NP_001177196
          Length = 491

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QCMFLRTKL 9
          +C+ LRTKL
Sbjct: 28 ECLDLRTKL 36
>XP_005267986
          Length = 2022

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +CMF RT+
Sbjct: 391 ECMFARTR 398
>XP_006715232
          Length = 7498

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5162 KCSFLETKL 5170
>XP_005249382
          Length = 5732

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 3287 KCSFLETKL 3295
>XP_005249381
          Length = 7281

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 4836 KCSFLETKL 4844
>XP_005249380
          Length = 7607

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5162 KCSFLETKL 5170
>XP_005249379
          Length = 7633

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5188 KCSFLETKL 5196
>XP_005249377
          Length = 7640

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5195 KCSFLETKL 5203
>XP_005249376
          Length = 7647

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5202 KCSFLETKL 5210
>XP_005249375
          Length = 7680

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5235 KCSFLETKL 5243
>XP_005249374
          Length = 7709

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5373 KCSFLETKL 5381
>XP_005249373
          Length = 7723

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5278 KCSFLETKL 5286
>XP_005249372
          Length = 7785

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5340 KCSFLETKL 5348
>XP_005249371
          Length = 7788

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5373 KCSFLETKL 5381
>XP_005249370
          Length = 7794

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5373 KCSFLETKL 5381
>XP_005249369
          Length = 7797

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5352 KCSFLETKL 5360
>XP_005249368
          Length = 7812

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5373 KCSFLETKL 5381
>XP_005249367
          Length = 7818

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QCMFLRTKL 9
            +C FL TKL
Sbjct: 5373 KCSFLETKL 5381
>XP_005246139
          Length = 624

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QCMFLRTKL 9
           +C+ LRTKL
Sbjct: 144 ECLDLRTKL 152
>NP_775901
          Length = 2226

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           CM+LR +L
Sbjct: 260 CMYLRNRL 267
>XP_006722498
          Length = 2059

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           CM+LR +L
Sbjct: 260 CMYLRNRL 267
>XP_006722497
          Length = 2227

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           CM+LR +L
Sbjct: 260 CMYLRNRL 267
>NP_001050
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QCMFLRTKL 9
           QC++ +TK+
Sbjct: 218 QCLYSKTKV 226
>NP_443188
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QCMFLRTKL 9
           QC  L+TKL
Sbjct: 178 QCPSLKTKL 186
>XP_006721080
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QCMFLRTKL 9
           QC  L+TKL
Sbjct: 178 QCPSLKTKL 186
>XP_006721079
          Length = 543

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QCMFLRTKL 9
           QC  L+TKL
Sbjct: 178 QCPSLKTKL 186
>XP_005255141
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QCMFLRTKL 9
           QC  L+TKL
Sbjct: 178 QCPSLKTKL 186
>NP_004527
          Length = 1403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>NP_075043
          Length = 1241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QCMFLRTK 8
          +C FLR+K
Sbjct: 61 RCEFLRSK 68
>XP_006725522
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006725521
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006725518
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QCMFLRTK 8
          +C FLR+K
Sbjct: 39 KCEFLRSK 46
>XP_006725517
          Length = 1348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006725516
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_005276859
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_005276858
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006726284
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QCMFLRTK 8
          +C FLR+K
Sbjct: 39 KCEFLRSK 46
>XP_006726283
          Length = 1348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006726282
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_005248581
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006714693
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006714691
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QCMFLRTK 8
          +C FLR+K
Sbjct: 39 KCEFLRSK 46
>XP_006714690
          Length = 1348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>XP_006714689
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCMFLRTK 8
           +C FLR+K
Sbjct: 223 KCEFLRSK 230
>NP_036342
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   QCMFLR 6
           QC+FL+
Sbjct: 354 QCLFLK 359
>NP_001093149
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   QCMFLR 6
           QC+FL+
Sbjct: 354 QCLFLK 359
>NP_777586
          Length = 148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1 QCMFLR 6
         QC FLR
Sbjct: 3 QCCFLR 8
>NP_001185599
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1 QCMFLR 6
         QC FLR
Sbjct: 3 QCCFLR 8
>NP_001018091
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>NP_001012999
          Length = 967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QCMFLRT 7
           +C FLRT
Sbjct: 383 ECGFLRT 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QCMFLRT 7
           +C FLRT
Sbjct: 540 ECGFLRT 546
>NP_065396
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_006725855
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_006725728
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_006725720
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_006725502
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_006725494
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_006725485
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_006725705
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   CMFLRTKL 9
           C+F +TK+
Sbjct: 304 CVFTQTKI 311
>XP_005251870
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   QCMFLR 6
           QC+FL+
Sbjct: 354 QCLFLK 359
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.350    0.145    0.486 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 434,507
Number of extensions: 632
Number of successful extensions: 74
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package