Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           19     869
NP_055903                                                              19     869
NP_066566                                                              16    5631
NP_997198                                                              16    5631
NP_060175                                                              16    7355
NP_001098024                                                           16    7355
XP_005254553                                                           16    7355
XP_005254552                                                           16    7355
XP_005254551                                                           16    7355
XP_006720646                                                           16    7355
NP_005215                                                              15    9605
NP_859052                                                              15    9605
NP_001008781                                                           15    9605
XP_005259570                                                           15    9605
XP_005259571                                                           15    9605
XP_005259569                                                           15    9605
XP_005268734                                                           15    9605
XP_006718827                                                           15    9605
NP_689653                                                              15    9605
>NP_001155973
          Length = 1833

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QAVLQTILS 9
           QAVLQT+LS
Sbjct: 601 QAVLQTLLS 609
>NP_055903
          Length = 1723

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QAVLQTILS 9
           QAVLQT+LS
Sbjct: 601 QAVLQTLLS 609
>NP_066566
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   QAVLQTIL 8
           QAV QTIL
Sbjct: 182 QAVYQTIL 189
>NP_997198
          Length = 449

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLQTILS 9
           + VLQT+LS
Sbjct: 432 EKVLQTVLS 440
>NP_060175
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AVLQTILS 9
           AVL TILS
Sbjct: 156 AVLNTILS 163
>NP_001098024
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AVLQTILS 9
           AVL TILS
Sbjct: 156 AVLNTILS 163
>XP_005254553
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  AVLQTILS 9
          AVL TILS
Sbjct: 41 AVLNTILS 48
>XP_005254552
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AVLQTILS 9
           AVL TILS
Sbjct: 142 AVLNTILS 149
>XP_005254551
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AVLQTILS 9
           AVL TILS
Sbjct: 156 AVLNTILS 163
>XP_006720646
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AVLQTILS 9
           AVL TILS
Sbjct: 156 AVLNTILS 163
>NP_005215
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QAVLQTIL 8
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>NP_859052
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QAVLQTI 7
           QAVLQT+
Sbjct: 460 QAVLQTM 466
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QAVLQTIL 8
            QAV +TIL
Sbjct: 1885 QAVFETIL 1892
>XP_005259570
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QAVLQTIL 8
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>XP_005259571
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QAVLQTIL 8
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>XP_005259569
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QAVLQTIL 8
          QAV++T+L
Sbjct: 4  QAVMETLL 11
>XP_005268734
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QAVLQTILS 9
          QAVL+T  S
Sbjct: 15 QAVLETFFS 23
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QAVLQTIL 8
           QAV +TIL
Sbjct: 775 QAVFETIL 782
>NP_689653
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QAVLQTILS 9
          QAVL+T  S
Sbjct: 15 QAVLETFFS 23
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.127    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 264,543
Number of extensions: 331
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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