Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_068765                                                              16    5631
XP_005262513                                                           16    5631
XP_006724842                                                           16    5631
XP_006724841                                                           16    5631
XP_006724840                                                           16    5631
XP_005262512                                                           16    5631
XP_005262511                                                           16    5631
XP_006724839                                                           16    5631
XP_005262510                                                           16    5631
XP_005262509                                                           16    5631
NP_076996                                                              15    9605
XP_006714561                                                           15    9605
>NP_068765
          Length = 1711

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>XP_005262513
          Length = 1655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>XP_006724842
          Length = 1687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 451 ADTSLVTA 458
>XP_006724841
          Length = 1687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 451 ADTSLVTA 458
>XP_006724840
          Length = 1785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>XP_005262512
          Length = 1785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>XP_005262511
          Length = 1785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>XP_006724839
          Length = 1785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>XP_005262510
          Length = 1785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>XP_005262509
          Length = 1785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASTSLVTA 9
           A TSLVTA
Sbjct: 549 ADTSLVTA 556
>NP_076996
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASTSLVTA 9
           ++TSLVTA
Sbjct: 174 SNTSLVTA 181
>XP_006714561
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASTSLVTA 9
           ++TSLVTA
Sbjct: 174 SNTSLVTA 181
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293   0.0953    0.202 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 173,972
Number of extensions: 93
Number of successful extensions: 12
Number of sequences better than 10000.0: 12
Number of HSP's gapped: 12
Number of HSP's successfully gapped: 12
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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