Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1135
NP_671714                                                              18    1135
XP_006715890                                                           18    1135
XP_005250160                                                           18    1135
XP_005250159                                                           18    1135
NP_001265003                                                           18    1935
NP_000084                                                              18    1935
NP_001161795                                                           17    3301
NP_660316                                                              17    3301
NP_001161796                                                           17    3301
NP_001161794                                                           17    3301
XP_005257133                                                           17    3301
XP_005257132                                                           17    3301
XP_006721785                                                           17    3301
XP_006721784                                                           17    3301
NP_036233                                                              17    4312
XP_005271544                                                           17    4312
NP_005215                                                              16    5631
NP_079001                                                              16    5631
NP_001007034                                                           16    5631
XP_005259572                                                           16    5631
XP_005259570                                                           16    5631
XP_005259571                                                           16    5631
XP_005259569                                                           16    5631
XP_006718975                                                           16    5631
XP_006718974                                                           16    5631
XP_006718973                                                           16    5631
XP_006718972                                                           16    5631
XP_005274350                                                           16    5631
XP_005274349                                                           16    5631
XP_005245269                                                           16    5631
XP_006711403                                                           16    5631
NP_036387                                                              16    5631
NP_653300                                                              16    5631
NP_001001734                                                           16    5631
NP_001946                                                              15    9605
NP_001161791                                                           15    9605
NP_114113                                                              15    9605
NP_060485                                                              15    9605
NP_733751                                                              15    9605
NP_001153505                                                           15    9605
NP_001186064                                                           15    9605
NP_597841                                                              15    9605
NP_004171                                                              15    9605
NP_065784                                                              15    9605
XP_006716142                                                           15    9605
XP_005250088                                                           15    9605
XP_006716141                                                           15    9605
XP_005250085                                                           15    9605
XP_006716140                                                           15    9605
XP_005250084                                                           15    9605
XP_005250083                                                           15    9605
XP_005250082                                                           15    9605
XP_005247723                                                           15    9605
XP_005246268                                                           15    9605
XP_005246267                                                           15    9605
XP_005246265                                                           15    9605
XP_005246264                                                           15    9605
XP_005246263                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASETRRNS 9
           QASET RNS
Sbjct: 246 QASETLRNS 254
>NP_671714
          Length = 3899

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASETRRNS 9
           QASET RNS
Sbjct: 246 QASETLRNS 254
>XP_006715890
          Length = 3860

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASETRRNS 9
           QASET RNS
Sbjct: 246 QASETLRNS 254
>XP_005250160
          Length = 3939

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASETRRNS 9
           QASET RNS
Sbjct: 246 QASETLRNS 254
>XP_005250159
          Length = 3952

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASETRRNS 9
           QASET RNS
Sbjct: 246 QASETLRNS 254
>NP_001265003
          Length = 1838

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    QASETRRN 8
            QAS TRRN
Sbjct: 1579 QASRTRRN 1586
>NP_000084
          Length = 1838

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    QASETRRN 8
            QAS TRRN
Sbjct: 1579 QASRTRRN 1586
>NP_001161795
          Length = 273

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 246 QATETQRN 253
>NP_660316
          Length = 332

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 280 QATETQRN 287
>NP_001161796
          Length = 233

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 195 QATETQRN 202
>NP_001161794
          Length = 307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 280 QATETQRN 287
>XP_005257133
          Length = 287

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 195 QATETQRN 202
>XP_005257132
          Length = 321

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 229 QATETQRN 236
>XP_006721785
          Length = 338

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 246 QATETQRN 253
>XP_006721784
          Length = 372

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QASETRRN 8
           QA+ET+RN
Sbjct: 280 QATETQRN 287
>NP_036233
          Length = 588

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QASETRRNS 9
           +  ETRRNS
Sbjct: 144 EPGETRRNS 152
>XP_005271544
          Length = 588

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QASETRRNS 9
           +  ETRRNS
Sbjct: 144 EPGETRRNS 152
>NP_005215
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QASETRRNS 9
           QASE+R++S
Sbjct: 498 QASESRQDS 506
>NP_079001
          Length = 544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ETRRNS 9
          ETRRNS
Sbjct: 8  ETRRNS 13
>NP_001007034
          Length = 209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ETRRNS 9
           ETRRNS
Sbjct: 195 ETRRNS 200
>XP_005259572
          Length = 342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QASETRRNS 9
           QASE+R++S
Sbjct: 247 QASESRQDS 255
>XP_005259570
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QASETRRNS 9
           QASE+R++S
Sbjct: 498 QASESRQDS 506
>XP_005259571
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QASETRRNS 9
           QASE+R++S
Sbjct: 498 QASESRQDS 506
>XP_005259569
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QASETRRNS 9
           QASE+R++S
Sbjct: 498 QASESRQDS 506
>XP_006718975
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ETRRNS 9
          ETRRNS
Sbjct: 8  ETRRNS 13
>XP_006718974
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ETRRNS 9
          ETRRNS
Sbjct: 8  ETRRNS 13
>XP_006718973
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ETRRNS 9
          ETRRNS
Sbjct: 8  ETRRNS 13
>XP_006718972
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ETRRNS 9
          ETRRNS
Sbjct: 8  ETRRNS 13
>XP_005274350
          Length = 544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ETRRNS 9
          ETRRNS
Sbjct: 8  ETRRNS 13
>XP_005274349
          Length = 544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ETRRNS 9
          ETRRNS
Sbjct: 8  ETRRNS 13
>XP_005245269
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SETRRNS 9
           S+TRRNS
Sbjct: 446 SKTRRNS 452
>XP_006711403
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SETRRNS 9
           S+TRRNS
Sbjct: 875 SKTRRNS 881
>NP_036387
          Length = 950

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ETRRNS 9
           ETRRNS
Sbjct: 673 ETRRNS 678
>NP_653300
          Length = 1029

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SETRRNS 9
           S+TRRNS
Sbjct: 943 SKTRRNS 949
>NP_001001734
          Length = 165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SETRRNS 9
          S+TRRNS
Sbjct: 79 SKTRRNS 85
>NP_001946
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SETRRNS 9
           SET RNS
Sbjct: 179 SETMRNS 185
>NP_001161791
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SETRRNS 9
           SET RNS
Sbjct: 178 SETMRNS 184
>NP_114113
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QASETRRN 8
           +A ET+RN
Sbjct: 809 KAKETKRN 816
>NP_060485
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASETRRNS 9
           ASET RN+
Sbjct: 573 ASETLRNA 580
>NP_733751
          Length = 4911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4046 KSSESRRN 4053
>NP_001153505
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    QASETR 6
            QASETR
Sbjct: 1255 QASETR 1260
>NP_001186064
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SETRRNS 9
          SETR+N+
Sbjct: 82 SETRKNN 88
>NP_597841
          Length = 119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SETRRNS 9
          SETR+N+
Sbjct: 82 SETRKNN 88
>NP_004171
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SETRRNS 9
          SETR+N+
Sbjct: 82 SETRKNN 88
>NP_065784
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASETRRNS 9
           A E+RRNS
Sbjct: 378 AVESRRNS 385
>XP_006716142
          Length = 4927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4062 KSSESRRN 4069
>XP_005250088
          Length = 4928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4063 KSSESRRN 4070
>XP_006716141
          Length = 4959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4094 KSSESRRN 4101
>XP_005250085
          Length = 4979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4118 KSSESRRN 4125
>XP_006716140
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4117 KSSESRRN 4124
>XP_005250084
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4117 KSSESRRN 4124
>XP_005250083
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4117 KSSESRRN 4124
>XP_005250082
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QASETRRN 8
            ++SE+RRN
Sbjct: 4118 KSSESRRN 4125
>XP_005247723
          Length = 1481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ASETRRNS 9
           A E+RRNS
Sbjct: 378 AVESRRNS 385
>XP_005246268
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SETRRNS 9
          SETR+N+
Sbjct: 83 SETRKNN 89
>XP_005246267
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SETRRNS 9
          SETR+N+
Sbjct: 83 SETRKNN 89
>XP_005246265
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SETRRNS 9
           SETR+N+
Sbjct: 141 SETRKNN 147
>XP_005246264
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SETRRNS 9
           SETR+N+
Sbjct: 189 SETRKNN 195
>XP_005246263
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SETRRNS 9
           SETR+N+
Sbjct: 190 SETRKNN 196
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289   0.0967    0.220 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 336,957
Number of extensions: 300
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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