Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              18    1482
NP_056144                                                              18    1482
XP_006722774                                                           18    1482
XP_005259895                                                           18    1482
XP_005259894                                                           18    1482
NP_005638                                                              17    3301
NP_001132940                                                           17    3301
NP_001132938                                                           17    3301
NP_001132939                                                           17    3301
NP_597713                                                              17    4312
NP_001166171                                                           17    4312
XP_006714597                                                           17    4312
XP_005271944                                                           17    4312
XP_005271943                                                           17    4312
XP_006714596                                                           17    4312
XP_005271942                                                           17    4312
NP_004463                                                              16    5631
NP_056132                                                              16    5631
NP_001269720                                                           16    5631
NP_001269681                                                           16    5631
NP_001269719                                                           16    5631
NP_001070820                                                           16    5631
NP_001070819                                                           16    5631
NP_060577                                                              16    5631
XP_006726455                                                           16    5631
XP_005267860                                                           16    5631
XP_005267859                                                           16    5631
XP_005267856                                                           16    5631
XP_005267858                                                           16    5631
XP_005267857                                                           16    5631
XP_005267855                                                           16    5631
XP_005267854                                                           16    5631
XP_006719747                                                           16    5631
XP_005269273                                                           16    5631
XP_006712226                                                           16    5631
XP_005262667                                                           16    5631
XP_005262666                                                           16    5631
XP_006712038                                                           16    5631
XP_006712037                                                           16    5631
XP_006712036                                                           16    5631
XP_006712035                                                           16    5631
XP_005262664                                                           16    5631
XP_005276116                                                           16    5631
NP_001156757                                                           16    7355
NP_001156758                                                           16    7355
NP_005234                                                              16    7355
NP_001156759                                                           16    7355
NP_053733                                                              16    7355
NP_005325                                                              16    7355
NP_079508                                                              16    7355
XP_005274721                                                           16    7355
XP_006724879                                                           16    7355
XP_006724878                                                           16    7355
XP_005261447                                                           16    7355
XP_006724230                                                           16    7355
XP_006724229                                                           16    7355
XP_005261446                                                           16    7355
XP_006716466                                                           16    7355
NP_005689                                                              15    9605
NP_005429                                                              15    9605
NP_443069                                                              15    9605
NP_064543                                                              15    9605
NP_006050                                                              15    9605
XP_006726271                                                           15    9605
XP_006726270                                                           15    9605
XP_006726269                                                           15    9605
XP_005274368                                                           15    9605
XP_006711170                                                           15    9605
XP_006711169                                                           15    9605
XP_006711168                                                           15    9605
>NP_005350
          Length = 552

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QASAAAQAA 9
           QA+AAAQAA
Sbjct: 455 QAAAAAQAA 463
>NP_056144
          Length = 613

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QASAAAQAA 9
          QA+AAAQAA
Sbjct: 4  QAAAAAQAA 12
>XP_006722774
          Length = 531

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QASAAAQAA 9
          QA+AAAQAA
Sbjct: 43 QAAAAAQAA 51
>XP_005259895
          Length = 624

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QASAAAQAA 9
          QA+AAAQAA
Sbjct: 43 QAAAAAQAA 51
>XP_005259894
          Length = 651

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QASAAAQAA 9
          QA+AAAQAA
Sbjct: 43 QAAAAAQAA 51
>NP_005638
          Length = 577

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QASAAA AA
Sbjct: 158 QASAAAAAA 166
>NP_001132940
          Length = 526

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QASAAA AA
Sbjct: 107 QASAAAAAA 115
>NP_001132938
          Length = 577

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QASAAA AA
Sbjct: 158 QASAAAAAA 166
>NP_001132939
          Length = 526

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QASAAA AA
Sbjct: 107 QASAAAAAA 115
>NP_597713
          Length = 847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           +A AAAQAA
Sbjct: 121 EAEAAAQAA 129
>NP_001166171
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           +A AAAQAA
Sbjct: 121 EAEAAAQAA 129
>XP_006714597
          Length = 490

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           +A AAAQAA
Sbjct: 121 EAEAAAQAA 129
>XP_005271944
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           +A AAAQAA
Sbjct: 121 EAEAAAQAA 129
>XP_005271943
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           +A AAAQAA
Sbjct: 121 EAEAAAQAA 129
>XP_006714596
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           +A AAAQAA
Sbjct: 121 EAEAAAQAA 129
>XP_005271942
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           +A AAAQAA
Sbjct: 121 EAEAAAQAA 129
>NP_004463
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 378 AAAAAQAA 385
>NP_056132
          Length = 1064

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>NP_001269720
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 416 SSAAAQAA 423
>NP_001269681
          Length = 1008

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 416 SSAAAQAA 423
>NP_001269719
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>NP_001070820
          Length = 405

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 355 AAAAAQAA 362
>NP_001070819
          Length = 439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 389 AAAAAQAA 396
>NP_060577
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 373 AAAAAQAA 380
>XP_006726455
          Length = 158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS A+QAA
Sbjct: 112 QASQASQAA 120
>XP_005267860
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 219 AAAAAQAA 226
>XP_005267859
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 219 AAAAAQAA 226
>XP_005267856
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 219 AAAAAQAA 226
>XP_005267858
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 219 AAAAAQAA 226
>XP_005267857
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 219 AAAAAQAA 226
>XP_005267855
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 219 AAAAAQAA 226
>XP_005267854
          Length = 421

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 371 AAAAAQAA 378
>XP_006719747
          Length = 230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 138 AAAAAQAA 145
>XP_005269273
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           A+AAAQAA
Sbjct: 138 AAAAAQAA 145
>XP_006712226
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS A+QAA
Sbjct: 215 QASQASQAA 223
>XP_005262667
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>XP_005262666
          Length = 987

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>XP_006712038
          Length = 1010

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 416 SSAAAQAA 423
>XP_006712037
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>XP_006712036
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>XP_006712035
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>XP_005262664
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ASAAAQAA 9
           +SAAAQAA
Sbjct: 472 SSAAAQAA 479
>XP_005276116
          Length = 75

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  QASAAAQAA 9
          QAS A+QAA
Sbjct: 47 QASQASQAA 55
>NP_001156757
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>NP_001156758
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>NP_005234
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>NP_001156759
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>NP_053733
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 115 QASYAAQSA 123
>NP_005325
          Length = 2035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ASAAAQAA 9
            A AAAQAA
Sbjct: 1618 AEAAAQAA 1625
>NP_079508
          Length = 257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ASAAAQAA 9
           ASAA QAA
Sbjct: 130 ASAAVQAA 137
>XP_005274721
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ASAAAQAA 9
            A AAAQAA
Sbjct: 1618 AEAAAQAA 1625
>XP_006724879
          Length = 2079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ASAAAQAA 9
            A AAAQAA
Sbjct: 1662 AEAAAQAA 1669
>XP_006724878
          Length = 2080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ASAAAQAA 9
            A AAAQAA
Sbjct: 1662 AEAAAQAA 1669
>XP_005261447
          Length = 613

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>XP_006724230
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>XP_006724229
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>XP_005261446
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QASAAAQAA 9
           QAS AAQ+A
Sbjct: 109 QASYAAQSA 117
>XP_006716466
          Length = 219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  ASAAAQAA 9
          ASAA QAA
Sbjct: 92 ASAAVQAA 99
>NP_005689
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 89 QASAAAATA 97
>NP_005429
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          Q  AAAQAA
Sbjct: 23 QPPAAAQAA 31
>NP_443069
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 63 QASAAAATA 71
>NP_064543
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QASAAAQAA 9
           Q  AAAQAA
Sbjct: 208 QCLAAAQAA 216
>NP_006050
          Length = 1575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QASAAAQAA 9
            QAS++ QAA
Sbjct: 1320 QASSSVQAA 1328
>XP_006726271
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 22 QASAAAATA 30
>XP_006726270
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 22 QASAAAATA 30
>XP_006726269
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 89 QASAAAATA 97
>XP_005274368
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          Q  AAAQAA
Sbjct: 23 QPPAAAQAA 31
>XP_006711170
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 22 QASAAAATA 30
>XP_006711169
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 22 QASAAAATA 30
>XP_006711168
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QASAAAQAA 9
          QASAAA  A
Sbjct: 89 QASAAAATA 97
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288   0.0821    0.167 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 147,574
Number of extensions: 225
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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