Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721991                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_001230694                                                           16    5631
NP_036329                                                              16    5631
NP_055845                                                              16    5631
NP_001230693                                                           16    5631
XP_006717095                                                           16    5631
XP_006717094                                                           16    5631
XP_005251923                                                           16    5631
XP_005248148                                                           16    5631
XP_005248147                                                           16    5631
XP_005248146                                                           16    5631
XP_005248145                                                           16    5631
XP_005248144                                                           16    5631
XP_005248143                                                           16    5631
XP_005248142                                                           16    5631
XP_005248141                                                           16    5631
XP_005248140                                                           16    5631
XP_005248139                                                           16    5631
XP_005245738                                                           16    5631
XP_006711755                                                           16    5631
XP_005245737                                                           16    5631
NP_005742                                                              16    7355
NP_671714                                                              16    7355
XP_006715890                                                           16    7355
XP_005250160                                                           16    7355
XP_005250159                                                           16    7355
NP_997320                                                              15    9605
NP_066267                                                              15    9605
XP_005253612                                                           15    9605
XP_006717852                                                           15    9605
XP_006717851                                                           15    9605
XP_006717850                                                           15    9605
XP_006717849                                                           15    9605
XP_006717848                                                           15    9605
XP_006717847                                                           15    9605
XP_006717846                                                           15    9605
XP_006717845                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 682 QAQTKLEV 689
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 682 QAQTKLEV 689
>XP_006721991
          Length = 1632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 692 QAQTKLEV 699
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 692 QAQTKLEV 699
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 692 QAQTKLEV 699
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 682 QAQTKLEV 689
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 692 QAQTKLEV 699
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 692 QAQTKLEV 699
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 679 QAQTKLEV 686
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 682 QAQTKLEV 689
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QAQTKLEV 8
           QAQTKLEV
Sbjct: 692 QAQTKLEV 699
>NP_001230694
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AQTKLEVV 9
           AQTKL++V
Sbjct: 306 AQTKLQLV 313
>NP_036329
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            AQTKL++V
Sbjct: 1015 AQTKLQLV 1022
>NP_055845
          Length = 3013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QAQTKLEVV 9
          QA+ K+EVV
Sbjct: 27 QAEKKIEVV 35
>NP_001230693
          Length = 253

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AQTKLEVV 9
           AQTKL++V
Sbjct: 189 AQTKLQLV 196
>XP_006717095
          Length = 900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AQTKLEVV 9
           AQTKL++V
Sbjct: 846 AQTKLQLV 853
>XP_006717094
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            AQTKL++V
Sbjct: 1015 AQTKLQLV 1022
>XP_005251923
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            AQTKL++V
Sbjct: 1015 AQTKLQLV 1022
>XP_005248148
          Length = 3028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QAQTKLEVV 9
          QA+ K+EVV
Sbjct: 27 QAEKKIEVV 35
>XP_005248147
          Length = 3028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QAQTKLEVV 9
          QA+ K+EVV
Sbjct: 27 QAEKKIEVV 35
>XP_005248146
          Length = 3073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAQTKLEVV 9
           QA+ K+EVV
Sbjct: 119 QAEKKIEVV 127
>XP_005248145
          Length = 3079

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QAQTKLEVV 9
          QA+ K+EVV
Sbjct: 78 QAEKKIEVV 86
>XP_005248144
          Length = 3099

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAQTKLEVV 9
           QA+ K+EVV
Sbjct: 119 QAEKKIEVV 127
>XP_005248143
          Length = 3105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAQTKLEVV 9
           QA+ K+EVV
Sbjct: 119 QAEKKIEVV 127
>XP_005248142
          Length = 3114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAQTKLEVV 9
           QA+ K+EVV
Sbjct: 119 QAEKKIEVV 127
>XP_005248141
          Length = 3119

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAQTKLEVV 9
           QA+ K+EVV
Sbjct: 119 QAEKKIEVV 127
>XP_005248140
          Length = 3119

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAQTKLEVV 9
           QA+ K+EVV
Sbjct: 119 QAEKKIEVV 127
>XP_005248139
          Length = 3120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAQTKLEVV 9
           QA+ K+EVV
Sbjct: 119 QAEKKIEVV 127
>XP_005245738
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AQTKLEVV 9
           AQTKL++V
Sbjct: 950 AQTKLQLV 957
>XP_006711755
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AQTKLEVV 9
           AQTKL++V
Sbjct: 987 AQTKLQLV 994
>XP_005245737
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AQTKLEVV 9
           AQTKL++V
Sbjct: 987 AQTKLQLV 994
>NP_005742
          Length = 3907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AQTKLEV 8
            AQTKLE+
Sbjct: 3169 AQTKLEL 3175
>NP_671714
          Length = 3899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AQTKLEV 8
            AQTKLE+
Sbjct: 3161 AQTKLEL 3167
>XP_006715890
          Length = 3860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AQTKLEV 8
            AQTKLE+
Sbjct: 3122 AQTKLEL 3128
>XP_005250160
          Length = 3939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AQTKLEV 8
            AQTKLE+
Sbjct: 3201 AQTKLEL 3207
>XP_005250159
          Length = 3952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AQTKLEV 8
            AQTKLE+
Sbjct: 3214 AQTKLEL 3220
>NP_997320
          Length = 4471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    QAQTKL 6
            QAQTKL
Sbjct: 2128 QAQTKL 2133
>NP_066267
          Length = 4377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 3460 SQSKLEVI 3467
>XP_005253612
          Length = 4589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    QAQTKL 6
            QAQTKL
Sbjct: 2246 QAQTKL 2251
>XP_006717852
          Length = 3508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 2591 SQSKLEVI 2598
>XP_006717851
          Length = 3513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 2596 SQSKLEVI 2603
>XP_006717850
          Length = 4364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 3447 SQSKLEVI 3454
>XP_006717849
          Length = 4383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 3466 SQSKLEVI 3473
>XP_006717848
          Length = 4392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 3475 SQSKLEVI 3482
>XP_006717847
          Length = 4395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 3478 SQSKLEVI 3485
>XP_006717846
          Length = 4396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 3479 SQSKLEVI 3486
>XP_006717845
          Length = 4397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    AQTKLEVV 9
            +Q+KLEV+
Sbjct: 3480 SQSKLEVI 3487
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.116    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 340,065
Number of extensions: 489
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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