Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              18    1135
NP_997175                                                              17    4312
NP_997180                                                              17    4312
NP_997177                                                              17    4312
NP_997178                                                              17    4312
NP_997179                                                              17    4312
NP_997176                                                              17    4312
NP_066368                                                              17    4312
XP_005247534                                                           17    4312
XP_005247533                                                           17    4312
XP_005247532                                                           17    4312
XP_005247531                                                           17    4312
XP_005247530                                                           17    4312
XP_005247529                                                           17    4312
XP_005247528                                                           17    4312
XP_005247527                                                           17    4312
XP_006713704                                                           17    4312
XP_006713703                                                           17    4312
XP_005247526                                                           17    4312
XP_005247525                                                           17    4312
XP_005247524                                                           17    4312
XP_005247523                                                           17    4312
XP_005247522                                                           17    4312
XP_005247521                                                           17    4312
XP_005247520                                                           17    4312
XP_005247519                                                           17    4312
XP_005247518                                                           17    4312
XP_005247517                                                           17    4312
XP_006713702                                                           17    4312
XP_005247516                                                           17    4312
XP_005247515                                                           17    4312
XP_005247514                                                           17    4312
NP_003165                                                              16    7355
XP_006717559                                                           16    7355
XP_006717558                                                           16    7355
XP_005252626                                                           16    7355
XP_005252623                                                           16    7355
NP_001035232                                                           15    9605
NP_066287                                                              15    9605
NP_001035233                                                           15    9605
NP_001878                                                              15    9605
XP_005246812                                                           15    9605
XP_005246811                                                           15    9605
XP_005246810                                                           15    9605
XP_005246808                                                           15    9605
XP_005246807                                                           15    9605
>NP_005350
          Length = 552

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QAATAQASA 9
           QAATAQA+A
Sbjct: 450 QAATAQAAA 458
>NP_997175
          Length = 370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>NP_997180
          Length = 342

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>NP_997177
          Length = 302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 188 QAAAAQAAA 196
>NP_997178
          Length = 314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 188 QAAAAQAAA 196
>NP_997179
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>NP_997176
          Length = 388

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>NP_066368
          Length = 382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>XP_005247534
          Length = 308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 164 QAAAAQAAA 172
>XP_005247533
          Length = 290

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 164 QAAAAQAAA 172
>XP_005247532
          Length = 308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 164 QAAAAQAAA 172
>XP_005247531
          Length = 308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 164 QAAAAQAAA 172
>XP_005247530
          Length = 308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 164 QAAAAQAAA 172
>XP_005247529
          Length = 308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 164 QAAAAQAAA 172
>XP_005247528
          Length = 342

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>XP_005247527
          Length = 343

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 199 QAAAAQAAA 207
>XP_006713704
          Length = 344

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 200 QAAAAQAAA 208
>XP_006713703
          Length = 344

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 200 QAAAAQAAA 208
>XP_005247526
          Length = 344

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 200 QAAAAQAAA 208
>XP_005247525
          Length = 361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247524
          Length = 379

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247523
          Length = 388

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>XP_005247522
          Length = 391

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247521
          Length = 400

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 256 QAAAAQAAA 264
>XP_005247520
          Length = 401

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247519
          Length = 413

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247518
          Length = 419

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247517
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_006713702
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247516
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247515
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>XP_005247514
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAATAQASA 9
           QAA AQA+A
Sbjct: 287 QAAAAQAAA 295
>NP_003165
          Length = 1788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AATAQASA 9
           AAT QASA
Sbjct: 353 AATLQASA 360
>XP_006717559
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AATAQASA 9
           AAT QASA
Sbjct: 431 AATLQASA 438
>XP_006717558
          Length = 1908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AATAQASA 9
           AAT QASA
Sbjct: 431 AATLQASA 438
>XP_005252626
          Length = 2260

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AATAQASA 9
           AAT QASA
Sbjct: 825 AATLQASA 832
>XP_005252623
          Length = 2302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AATAQASA 9
           AAT QASA
Sbjct: 825 AATLQASA 832
>NP_001035232
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 461 QAAAAAASA 469
>NP_066287
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 461 QAAAAAASA 469
>NP_001035233
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 461 QAAAAAASA 469
>NP_001878
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QAATAQASA 9
          QAA A ASA
Sbjct: 3  QAAKASASA 11
>XP_005246812
          Length = 1754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 210 QAAAAAASA 218
>XP_005246811
          Length = 1995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 451 QAAAAAASA 459
>XP_005246810
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 461 QAAAAAASA 469
>XP_005246808
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 461 QAAAAAASA 469
>XP_005246807
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAATAQASA 9
           QAA A ASA
Sbjct: 461 QAAAAAASA 469
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285   0.0815    0.169 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 125,157
Number of extensions: 246
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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