Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_001718723                                                           19     869
NP_001177666                                                           16    7355
NP_001035829                                                           16    7355
NP_001166996                                                           16    7355
NP_004591                                                              16    7355
NP_001166995                                                           16    7355
NP_001269716                                                           16    7355
NP_001035828                                                           16    7355
XP_005251528                                                           16    7355
XP_006716838                                                           16    7355
XP_006716837                                                           16    7355
XP_005251526                                                           16    7355
XP_005251525                                                           16    7355
XP_006716836                                                           16    7355
XP_005251524                                                           16    7355
XP_006711560                                                           16    7355
XP_006711559                                                           16    7355
XP_006711558                                                           16    7355
NP_001123520                                                           15    9605
NP_001123521                                                           15    9605
NP_001123522                                                           15    9605
NP_056111                                                              15    9605
NP_001138239                                                           15    9605
NP_001066                                                              15    9605
XP_006720004                                                           15    9605
XP_005254093                                                           15    9605
XP_006720003                                                           15    9605
XP_006720002                                                           15    9605
XP_005254092                                                           15    9605
XP_006720001                                                           15    9605
XP_006720000                                                           15    9605
XP_005254091                                                           15    9605
XP_006719999                                                           15    9605
XP_006719998                                                           15    9605
XP_006719997                                                           15    9605
XP_006719996                                                           15    9605
XP_006719995                                                           15    9605
XP_006719994                                                           15    9605
XP_006719993                                                           15    9605
XP_006719992                                                           15    9605
XP_006719991                                                           15    9605
XP_006719990                                                           15    9605
XP_006719989                                                           15    9605
XP_006719988                                                           15    9605
XP_006719987                                                           15    9605
XP_006719986                                                           15    9605
XP_006719985                                                           15    9605
>XP_001718723
          Length = 1091

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PVTASMTMR 9
           P+T+SMT+R
Sbjct: 899 PITSSMTLR 907
>NP_001177666
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 445 PVTLSMT 451
>NP_001035829
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 423 PVTTDMTLQ 431
>NP_001166996
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 423 PVTTDMTLQ 431
>NP_004591
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 423 PVTTDMTLQ 431
>NP_001166995
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 423 PVTTDMTLQ 431
>NP_001269716
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 193 PVTLSMT 199
>NP_001035828
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 423 PVTTDMTLQ 431
>XP_005251528
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 193 PVTLSMT 199
>XP_006716838
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 445 PVTLSMT 451
>XP_006716837
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 445 PVTLSMT 451
>XP_005251526
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 445 PVTLSMT 451
>XP_005251525
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 441 PVTLSMT 447
>XP_006716836
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 444 PVTLSMT 450
>XP_005251524
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVTASMT 7
           PVT SMT
Sbjct: 445 PVTLSMT 451
>XP_006711560
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 423 PVTTDMTLQ 431
>XP_006711559
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 445 PVTTDMTLQ 453
>XP_006711558
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVTASMTMR 9
           PVT  MT++
Sbjct: 445 PVTTDMTLQ 453
>NP_001123520
          Length = 2068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1188 PVNAGMTVK 1196
>NP_001123521
          Length = 1254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>NP_001123522
          Length = 1253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1188 PVNAGMTVK 1196
>NP_056111
          Length = 2069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>NP_001138239
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTASMTMR 9
           P T S TMR
Sbjct: 158 PTTLSETMR 166
>NP_001066
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTASMTMR 9
           P T S TMR
Sbjct: 242 PTTLSETMR 250
>XP_006720004
          Length = 1412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_005254093
          Length = 2046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>XP_006720003
          Length = 2058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1117 PVNAGMTVK 1125
>XP_006720002
          Length = 2058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1117 PVNAGMTVK 1125
>XP_005254092
          Length = 2062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>XP_006720001
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006720000
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>XP_005254091
          Length = 2093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>XP_006719999
          Length = 2095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719998
          Length = 2103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719997
          Length = 2104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719996
          Length = 2104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719995
          Length = 2106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1188 PVNAGMTVK 1196
>XP_006719994
          Length = 2107

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>XP_006719993
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719992
          Length = 2116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719991
          Length = 2118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719990
          Length = 2118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719989
          Length = 2127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719988
          Length = 2129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1188 PVNAGMTVK 1196
>XP_006719987
          Length = 2130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1189 PVNAGMTVK 1197
>XP_006719986
          Length = 2139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
>XP_006719985
          Length = 2141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PVTASMTMR 9
            PV A MT++
Sbjct: 1200 PVNAGMTVK 1208
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.114    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 262,236
Number of extensions: 378
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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