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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              19     665
NP_001263689                                                           19     665
NP_001119584                                                           19     665
NP_001119586                                                           19     665
NP_001263625                                                           19     665
NP_001119590                                                           19     665
NP_001263690                                                           19     665
NP_001119585                                                           19     665
NP_001263624                                                           19     665
NP_001119588                                                           19     665
NP_001119587                                                           19     665
NP_001119589                                                           19     665
NP_001108451                                                           17    4312
NP_001108454                                                           17    4312
NP_003713                                                              17    4312
NP_001108450                                                           17    4312
NP_001108452                                                           17    4312
NP_001108453                                                           17    4312
NP_001191121                                                           17    4312
NP_001119713                                                           17    4312
NP_001191117                                                           17    4312
NP_001119712                                                           17    4312
NP_001119714                                                           17    4312
NP_005418                                                              17    4312
NP_001191116                                                           17    4312
NP_001191115                                                           17    4312
NP_001191119                                                           17    4312
NP_001191113                                                           17    4312
NP_001191118                                                           17    4312
NP_001191120                                                           17    4312
NP_001191114                                                           17    4312
XP_005247903                                                           17    4312
XP_005247901                                                           17    4312
XP_005247900                                                           17    4312
NP_055448                                                              17    4312
NP_001013758                                                           15    9605
NP_067045                                                              15    9605
XP_005245454                                                           15    9605
XP_005245453                                                           15    9605
XP_005245450                                                           15    9605

>NP_000537
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 157 VRAMAIYK 164



>NP_001263689
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 118 VRAMAIYK 125



>NP_001119584
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 157 VRAMAIYK 164



>NP_001119586
          Length = 341

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 157 VRAMAIYK 164



>NP_001263625
          Length = 302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 118 VRAMAIYK 125



>NP_001119590
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 118 VRAMAIYK 125



>NP_001263690
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 118 VRAMAIYK 125



>NP_001119585
          Length = 346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 157 VRAMAIYK 164



>NP_001263624
          Length = 307

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRAMAIYK 9
           VRAMAIYK
Sbjct: 118 VRAMAIYK 125



>NP_001119588
          Length = 209

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  VRAMAIYK 9
          VRAMAIYK
Sbjct: 25 VRAMAIYK 32



>NP_001119587
          Length = 261

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  VRAMAIYK 9
          VRAMAIYK
Sbjct: 25 VRAMAIYK 32



>NP_001119589
          Length = 214

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  VRAMAIYK 9
          VRAMAIYK
Sbjct: 25 VRAMAIYK 32



>NP_001108451
          Length = 487

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 225 IRAMPVYK 232



>NP_001108454
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 131 IRAMPVYK 138



>NP_003713
          Length = 680

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 225 IRAMPVYK 232



>NP_001108450
          Length = 555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 225 IRAMPVYK 232



>NP_001108452
          Length = 586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 131 IRAMPVYK 138



>NP_001108453
          Length = 461

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 131 IRAMPVYK 138



>NP_001191121
          Length = 565

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 104 IRAMPVYK 111



>NP_001119713
          Length = 450

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 126 IRAMPVYK 133



>NP_001191117
          Length = 540

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 175 IRAMPVYK 182



>NP_001119712
          Length = 587

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 126 IRAMPVYK 133



>NP_001119714
          Length = 426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 126 IRAMPVYK 133



>NP_005418
          Length = 636

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 175 IRAMPVYK 182



>NP_001191116
          Length = 555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 175 IRAMPVYK 182



>NP_001191115
          Length = 403

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 175 IRAMPVYK 182



>NP_001191119
          Length = 506

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 126 IRAMPVYK 133



>NP_001191113
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 175 IRAMPVYK 182



>NP_001191118
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 126 IRAMPVYK 133



>NP_001191120
          Length = 491

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 126 IRAMPVYK 133



>NP_001191114
          Length = 475

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 175 IRAMPVYK 182



>XP_005247903
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 225 IRAMPVYK 232



>XP_005247901
          Length = 663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 208 IRAMPVYK 215



>XP_005247900
          Length = 676

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRAMAIYK 9
           +RAM +YK
Sbjct: 225 IRAMPVYK 232



>NP_055448
          Length = 1173

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RAMAIYK 9
           RA+AIYK
Sbjct: 631 RALAIYK 637



>NP_001013758
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    RAMAIYK 9
            RAM +YK
Sbjct: 1017 RAMQVYK 1023



>NP_067045
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVRAMAIY 8
           PVR +AI+
Sbjct: 295 PVRQLAIF 302



>XP_005245454
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVRAMAIY 8
           PVR +AI+
Sbjct: 113 PVRQLAIF 120



>XP_005245453
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVRAMAIY 8
           PVR +AI+
Sbjct: 113 PVRQLAIF 120



>XP_005245450
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVRAMAIY 8
           PVR +AI+
Sbjct: 265 PVRQLAIF 272



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.137    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 301,281
Number of extensions: 446
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)