Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_001157973                                                           17    2528
NP_062817                                                              17    2528
XP_005261745                                                           17    2528
XP_005261744                                                           17    2528
XP_005261743                                                           17    2528
XP_006724347                                                           17    2528
XP_006724346                                                           17    2528
XP_006724345                                                           17    2528
XP_006724344                                                           17    2528
NP_001157974                                                           17    2528
NP_689824                                                              17    3301
NP_001152849                                                           16    5631
NP_001152850                                                           16    5631
NP_073601                                                              16    5631
NP_001152851                                                           16    5631
NP_001152852                                                           16    5631
XP_005256170                                                           16    5631
XP_005256156                                                           16    5631
XP_006721314                                                           16    5631
XP_006721313                                                           16    5631
XP_006721312                                                           16    5631
XP_006721311                                                           16    5631
XP_006721310                                                           16    5631
XP_005256163                                                           16    5631
XP_005256162                                                           16    5631
XP_005256158                                                           16    5631
XP_005256160                                                           16    5631
XP_005256157                                                           16    5631
NP_001167635                                                           16    7355
NP_001108198                                                           16    7355
NP_001135906                                                           16    7355
NP_036347                                                              16    7355
NP_004625                                                              16    7355
NP_001003694                                                           16    7355
XP_005250401                                                           16    7355
XP_006716048                                                           16    7355
XP_006716047                                                           16    7355
XP_005250400                                                           16    7355
XP_005250399                                                           16    7355
XP_005265508                                                           16    7355
XP_005265507                                                           16    7355
XP_005265506                                                           16    7355
NP_787128                                                              15    9605
NP_002808                                                              15    9605
NP_009135                                                              15    9605
NP_001128206                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2916 PVLSSLLAN 2924
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2933 PVLSSLLAN 2941
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2933 PVLSSLLAN 2941
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2933 PVLSSLLAN 2941
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2933 PVLSSLLAN 2941
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2933 PVLSSLLAN 2941
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2933 PVLSSLLAN 2941
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2932 PVLSSLLAN 2940
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PVLSSLRAN 9
            PVLSSL AN
Sbjct: 2933 PVLSSLLAN 2941
>NP_001157973
          Length = 985

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 411 PLLSSLSAN 419
>NP_062817
          Length = 985

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 411 PLLSSLSAN 419
>XP_005261745
          Length = 986

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 411 PLLSSLSAN 419
>XP_005261744
          Length = 986

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 411 PLLSSLSAN 419
>XP_005261743
          Length = 986

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 411 PLLSSLSAN 419
>XP_006724347
          Length = 1002

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 452 PLLSSLSAN 460
>XP_006724346
          Length = 1003

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 452 PLLSSLSAN 460
>XP_006724345
          Length = 1026

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 452 PLLSSLSAN 460
>XP_006724344
          Length = 1027

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 452 PLLSSLSAN 460
>NP_001157974
          Length = 811

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+LSSL AN
Sbjct: 248 PLLSSLSAN 256
>NP_689824
          Length = 740

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P LSSLRA
Sbjct: 143 PALSSLRA 150
>NP_001152849
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 237 PILRSLRA 244
>NP_001152850
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 237 PILRSLRA 244
>NP_073601
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 236 PILRSLRA 243
>NP_001152851
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 236 PILRSLRA 243
>NP_001152852
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 217 PILRSLRA 224
>XP_005256170
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 217 PILRSLRA 224
>XP_005256156
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 217 PILRSLRA 224
>XP_006721314
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PVLSSLRA 8
          P+L SLRA
Sbjct: 74 PILRSLRA 81
>XP_006721313
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PVLSSLRA 8
          P+L SLRA
Sbjct: 74 PILRSLRA 81
>XP_006721312
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PVLSSLRA 8
          P+L SLRA
Sbjct: 74 PILRSLRA 81
>XP_006721311
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PVLSSLRA 8
          P+L SLRA
Sbjct: 74 PILRSLRA 81
>XP_006721310
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PVLSSLRA 8
          P+L SLRA
Sbjct: 74 PILRSLRA 81
>XP_005256163
          Length = 241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 95  PILRSLRA 102
>XP_005256162
          Length = 241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 95  PILRSLRA 102
>XP_005256158
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 217 PILRSLRA 224
>XP_005256160
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 217 PILRSLRA 224
>XP_005256157
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVLSSLRA 8
           P+L SLRA
Sbjct: 217 PILRSLRA 224
>NP_001167635
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+L SLRA+
Sbjct: 198 PLLPSLRAS 206
>NP_001108198
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+L SLRA+
Sbjct: 198 PLLPSLRAS 206
>NP_001135906
          Length = 863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLSSLRAN 9
           +LSSL+AN
Sbjct: 811 LLSSLKAN 818
>NP_036347
          Length = 916

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLSSLRAN 9
           +LSSL+AN
Sbjct: 864 LLSSLKAN 871
>NP_004625
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVLSSLR 7
           P++SSLR
Sbjct: 934 PIMSSLR 940
>NP_001003694
          Length = 1220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVLSSLR 7
           P++SSLR
Sbjct: 940 PIMSSLR 946
>XP_005250401
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+L SLRA+
Sbjct: 198 PLLPSLRAS 206
>XP_006716048
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+L SLRA+
Sbjct: 198 PLLPSLRAS 206
>XP_006716047
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+L SLRA+
Sbjct: 198 PLLPSLRAS 206
>XP_005250400
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+L SLRA+
Sbjct: 198 PLLPSLRAS 206
>XP_005250399
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVLSSLRAN 9
           P+L SLRA+
Sbjct: 198 PLLPSLRAS 206
>XP_005265508
          Length = 1213

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVLSSLR 7
           P++SSLR
Sbjct: 933 PIMSSLR 939
>XP_005265507
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVLSSLR 7
           P++SSLR
Sbjct: 939 PIMSSLR 945
>XP_005265506
          Length = 1247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVLSSLR 7
           P++SSLR
Sbjct: 933 PIMSSLR 939
>NP_787128
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVLSSLR 7
           PVL SLR
Sbjct: 222 PVLESLR 228
>NP_002808
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PVLSSLR 7
           PVL SLR
Sbjct: 220 PVLESLR 226
>NP_009135
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PVLSSLRA 8
          PVL  LRA
Sbjct: 72 PVLEGLRA 79
>NP_001128206
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVLSSLRAN 9
           PV+ +LR N
Sbjct: 92  PVVGTLRGN 100
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.124    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 344,034
Number of extensions: 656
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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