Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_066124                                                              20     390
XP_006717999                                                           20     390
NP_002408                                                              18    1482
NP_001139438                                                           18    1482
XP_006717927                                                           18    1482
XP_006711326                                                           17    3301
XP_005273145                                                           17    3301
XP_006711325                                                           17    3301
NP_066018                                                              17    4312
XP_005260531                                                           17    4312
NP_055730                                                              16    5631
NP_001242982                                                           16    5631
NP_002877                                                              16    5631
NP_001043                                                              16    5631
NP_067006                                                              16    5631
NP_001258115                                                           16    5631
XP_006717495                                                           16    5631
XP_006717492                                                           16    5631
XP_006717491                                                           16    5631
XP_006717489                                                           16    5631
XP_006717488                                                           16    5631
XP_006717487                                                           16    5631
XP_006717486                                                           16    5631
XP_006710290                                                           16    5631
NP_066361                                                              16    5631
NP_000066                                                              16    7355
NP_001789                                                              15    9605
NP_439892                                                              15    9605
NP_001181926                                                           15    9605
NP_001014437                                                           15    9605
NP_065128                                                              15    9605
NP_001742                                                              15    9605
NP_001135943                                                           15    9605
NP_644802                                                              15    9605
NP_835224                                                              15    9605
NP_001191031                                                           15    9605
NP_001191030                                                           15    9605
NP_001076442                                                           15    9605
NP_001076441                                                           15    9605
NP_001258594                                                           15    9605
NP_060742                                                              15    9605
NP_775901                                                              15    9605
NP_055535                                                              15    9605
NP_005966                                                              15    9605
XP_006725193                                                           15    9605
XP_006725192                                                           15    9605
XP_005266736                                                           15    9605
XP_006722498                                                           15    9605
XP_006722497                                                           15    9605
XP_006719165                                                           15    9605
XP_005253468                                                           15    9605
XP_006719164                                                           15    9605
XP_005253464                                                           15    9605
XP_006719163                                                           15    9605
XP_005253463                                                           15    9605
XP_006718404                                                           15    9605
XP_006718403                                                           15    9605
XP_005270358                                                           15    9605
XP_005263206                                                           15    9605
XP_005263205                                                           15    9605
XP_005247001                                                           15    9605
NP_849150                                                              15    9605
>NP_066124
          Length = 1114

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PSVAKLMDT 9
            PS AKLMDT
Sbjct: 1103 PSAAKLMDT 1111
>XP_006717999
          Length = 1207

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PSVAKLMDT 9
            PS AKLMDT
Sbjct: 1196 PSAAKLMDT 1204
>NP_002408
          Length = 3256

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PSVAKLMDT 9
            PSV K MDT
Sbjct: 2260 PSVGKAMDT 2268

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PSVAKLMDT 9
            PS  K MDT
Sbjct: 2381 PSAGKAMDT 2389
>NP_001139438
          Length = 2896

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PSVAKLMDT 9
            PSV K MDT
Sbjct: 1900 PSVGKAMDT 1908

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PSVAKLMDT 9
            PS  K MDT
Sbjct: 2021 PSAGKAMDT 2029
>XP_006717927
          Length = 2406

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PSVAKLMDT 9
            PSV K MDT
Sbjct: 1410 PSVGKAMDT 1418

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PSVAKLMDT 9
            PS  K MDT
Sbjct: 1531 PSAGKAMDT 1539
>XP_006711326
          Length = 694

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSV+ L+DT
Sbjct: 12 PSVSSLVDT 20
>XP_005273145
          Length = 845

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSV+ L+DT
Sbjct: 12 PSVSSLVDT 20
>XP_006711325
          Length = 864

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSV+ L+DT
Sbjct: 12 PSVSSLVDT 20
>NP_066018
          Length = 579

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSVAKLMDT 9
           PSV K +DT
Sbjct: 538 PSVQKALDT 546
>XP_005260531
          Length = 474

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSVAKLMDT 9
           PSV K +DT
Sbjct: 433 PSVQKALDT 441
>NP_055730
          Length = 1710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>NP_001242982
          Length = 1709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>NP_002877
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSV +++DT
Sbjct: 50 PSVLEILDT 58
>NP_001043
          Length = 388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   PSVAKLMD 8
           PSVAKL++
Sbjct: 160 PSVAKLIN 167
>NP_067006
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSV +++DT
Sbjct: 50 PSVLEILDT 58
>NP_001258115
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSV +++DT
Sbjct: 50 PSVLEILDT 58
>XP_006717495
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>XP_006717492
          Length = 1635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>XP_006717491
          Length = 1677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>XP_006717489
          Length = 1945

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>XP_006717488
          Length = 2031

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>XP_006717487
          Length = 2071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>XP_006717486
          Length = 2072

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PSVAKLM 7
           PS+AKLM
Sbjct: 276 PSLAKLM 282
>XP_006710290
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVAKLMD 8
           SVAK+MD
Sbjct: 502 SVAKMMD 508
>NP_066361
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSV +++DT
Sbjct: 50 PSVLEILDT 58
>NP_000066
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PSVAKLMD 8
          P+V +LMD
Sbjct: 69 PNVVRLMD 76
>NP_001789
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  PSVAKLMD 8
          P++ KL+D
Sbjct: 61 PNIVKLLD 68
>NP_439892
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  PSVAKLMD 8
          P++ KL+D
Sbjct: 61 PNIVKLLD 68
>NP_001181926
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 719 PTVVKLVD 726
>NP_001014437
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 719 PTVVKLVD 726
>NP_065128
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PSVAKLMDT 9
           PS AKL  T
Sbjct: 305 PSTAKLSST 313
>NP_001742
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 636 PTVVKLVD 643
>NP_001135943
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PSVAKLMDT 9
           PS AKL  T
Sbjct: 305 PSTAKLSST 313
>NP_644802
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 636 PTVVKLVD 643
>NP_835224
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSVAKLMDT 9
           P V KL+D+
Sbjct: 245 PQVMKLLDS 253
>NP_001191031
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSVA+ M+T
Sbjct: 67 PSVAQEMNT 75
>NP_001191030
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSVA+ M+T
Sbjct: 48 PSVAQEMNT 56
>NP_001076442
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSVAKLMDT 9
           PSVA+ M+T
Sbjct: 107 PSVAQEMNT 115
>NP_001076441
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSVAKLMDT 9
           PSVA+ M+T
Sbjct: 171 PSVAQEMNT 179
>NP_001258594
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P++ K+MD
Sbjct: 181 PTILKMMD 188
>NP_060742
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSVAKLMDT 9
           PSVA+ M+T
Sbjct: 113 PSVAQEMNT 121
>NP_775901
          Length = 2226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PSVAKLMD 8
            P+VA L+D
Sbjct: 1822 PTVASLLD 1829
>NP_055535
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  PSVAKLMD 8
          P++ KL+D
Sbjct: 89 PNIVKLLD 96
>NP_005966
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PSVAKLMDT 9
           PSV KLM T
Sbjct: 414 PSVHKLMLT 422
>XP_006725193
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 626 PTVVKLVD 633
>XP_006725192
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 719 PTVVKLVD 726
>XP_005266736
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+VA L+D
Sbjct: 910 PTVASLLD 917
>XP_006722498
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PSVAKLMD 8
            P+VA L+D
Sbjct: 1823 PTVASLLD 1830
>XP_006722497
          Length = 2227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PSVAKLMD 8
            P+VA L+D
Sbjct: 1823 PTVASLLD 1830
>XP_006719165
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSVAKLMDT 9
           PSVA+ M+T
Sbjct: 107 PSVAQEMNT 115
>XP_005253468
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSVA+ M+T
Sbjct: 67 PSVAQEMNT 75
>XP_006719164
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSVAKLMDT 9
           PSVA+ M+T
Sbjct: 171 PSVAQEMNT 179
>XP_005253464
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSVA+ M+T
Sbjct: 67 PSVAQEMNT 75
>XP_006719163
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PSVAKLMDT 9
          PSVA+ M+T
Sbjct: 81 PSVAQEMNT 89
>XP_005253463
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSVAKLMDT 9
           PSVA+ M+T
Sbjct: 171 PSVAQEMNT 179
>XP_006718404
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 626 PTVVKLVD 633
>XP_006718403
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSVAKLMD 8
           P+V KL+D
Sbjct: 719 PTVVKLVD 726
>XP_005270358
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  PSVAKLMD 8
          P++ KL+D
Sbjct: 89 PNIVKLLD 96
>XP_005263206
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PSVAKLMDT 9
           PS AKL  T
Sbjct: 305 PSTAKLSST 313
>XP_005263205
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PSVAKLMDT 9
           PS AKL  T
Sbjct: 305 PSTAKLSST 313
>XP_005247001
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSVAKLMDT 9
           P V KL+D+
Sbjct: 245 PQVMKLLDS 253
>NP_849150
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSVAKLMDT 9
           P V KL++T
Sbjct: 359 PDVQKLLET 367
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.121    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,388
Number of extensions: 810
Number of successful extensions: 65
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package