Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           22     134
NP_858045                                                              22     134
NP_006525                                                              22     134
NP_001167559                                                           22     134
NP_003296                                                              18    1935
NP_001124170                                                           18    1935
NP_068817                                                              18    1935
NP_001239160                                                           18    1935
XP_005271911                                                           18    1935
NP_005579                                                              17    2528
NP_036230                                                              17    3301
NP_055481                                                              17    3301
NP_001182485                                                           17    3301
NP_001182484                                                           17    3301
NP_113646                                                              17    3301
NP_001139578                                                           17    3301
NP_001139577                                                           17    3301
NP_001139576                                                           17    3301
NP_001139575                                                           17    3301
NP_001139574                                                           17    3301
XP_006717093                                                           17    3301
XP_005247877                                                           17    3301
NP_783161                                                              17    4312
NP_002842                                                              17    4312
XP_005250576                                                           17    4312
XP_005250008                                                           17    4312
XP_006715921                                                           17    4312
XP_005250007                                                           17    4312
NP_542376                                                              16    5631
NP_004361                                                              16    5631
XP_006715397                                                           16    5631
NP_001175                                                              16    7355
NP_001026849                                                           16    7355
NP_001180389                                                           16    7355
NP_001180390                                                           16    7355
NP_932346                                                              16    7355
NP_004280                                                              16    7355
NP_060485                                                              16    7355
NP_001171711                                                           16    7355
NP_001273028                                                           16    7355
NP_060733                                                              16    7355
NP_001013683                                                           16    7355
NP_005272                                                              16    7355
NP_005275                                                              16    7355
XP_006712103                                                           16    7355
XP_006712102                                                           16    7355
NP_849189                                                              15    9605
NP_775809                                                              15    9605
NP_001273700                                                           15    9605
NP_115593                                                              15    9605
NP_942592                                                              15    9605
XP_005269574                                                           15    9605
XP_006717681                                                           15    9605
XP_006716575                                                           15    9605
XP_005265728                                                           15    9605
XP_005265724                                                           15    9605
>NP_001167558
          Length = 1423

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PSFNSMINQ 9
            PSFNSM+NQ
Sbjct: 1133 PSFNSMMNQ 1141
>NP_858045
          Length = 1424

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PSFNSMINQ 9
            PSFNSM+NQ
Sbjct: 1133 PSFNSMMNQ 1141
>NP_006525
          Length = 1420

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PSFNSMINQ 9
            PSFNSM+NQ
Sbjct: 1133 PSFNSMMNQ 1141
>NP_001167559
          Length = 1415

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PSFNSMINQ 9
            PSFNSM+NQ
Sbjct: 1128 PSFNSMMNQ 1136
>NP_003296
          Length = 848

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SFNSMINQ 9
           SFNS++NQ
Sbjct: 764 SFNSILNQ 771
>NP_001124170
          Length = 921

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SFNSMINQ 9
           SFNS++NQ
Sbjct: 837 SFNSILNQ 844
>NP_068817
          Length = 1093

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           P FNS +NQ
Sbjct: 237 PLFNSAVNQ 245
>NP_001239160
          Length = 613

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           P FNS +NQ
Sbjct: 237 PLFNSAVNQ 245
>XP_005271911
          Length = 613

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           P FNS +NQ
Sbjct: 237 PLFNSAVNQ 245
>NP_005579
          Length = 746

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           P FNS+I Q
Sbjct: 233 PEFNSIIGQ 241
>NP_036230
          Length = 493

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSFNSMINQ 9
           P++N +INQ
Sbjct: 228 PTYNRIINQ 236
>NP_055481
          Length = 625

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           PS N+MI Q
Sbjct: 501 PSLNTMIQQ 509
>NP_001182485
          Length = 625

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           PS N+MI Q
Sbjct: 501 PSLNTMIQQ 509
>NP_001182484
          Length = 643

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           PS N+MI Q
Sbjct: 519 PSLNTMIQQ 527
>NP_113646
          Length = 854

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFNSMI 7
           PSFN+M+
Sbjct: 307 PSFNAMV 313
>NP_001139578
          Length = 710

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFNSMI 7
           PSFN+M+
Sbjct: 272 PSFNAMV 278
>NP_001139577
          Length = 819

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFNSMI 7
           PSFN+M+
Sbjct: 272 PSFNAMV 278
>NP_001139576
          Length = 819

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFNSMI 7
           PSFN+M+
Sbjct: 272 PSFNAMV 278
>NP_001139575
          Length = 819

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFNSMI 7
           PSFN+M+
Sbjct: 272 PSFNAMV 278
>NP_001139574
          Length = 854

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFNSMI 7
           PSFN+M+
Sbjct: 307 PSFNAMV 313
>XP_006717093
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSFNSMINQ 9
           P++N +INQ
Sbjct: 228 PTYNRIINQ 236
>XP_005247877
          Length = 854

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFNSMI 7
           PSFN+M+
Sbjct: 307 PSFNAMV 313
>NP_783161
          Length = 665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSFN M++
Sbjct: 495 PSFNQMLD 502
>NP_002842
          Length = 2315

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    PSFNSMI 7
            PSFN M+
Sbjct: 1057 PSFNEMV 1063
>XP_005250576
          Length = 2308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    PSFNSMI 7
            PSFN M+
Sbjct: 1057 PSFNEMV 1063
>XP_005250008
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSFN M++
Sbjct: 286 PSFNQMLD 293
>XP_006715921
          Length = 665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSFN M++
Sbjct: 495 PSFNQMLD 502
>XP_005250007
          Length = 665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSFN M++
Sbjct: 495 PSFNQMLD 502
>NP_542376
          Length = 1899

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FNSMINQ 9
            FN M+NQ
Sbjct: 1759 FNQMLNQ 1765
>NP_004361
          Length = 3063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FNSMINQ 9
            FN M+NQ
Sbjct: 2923 FNQMLNQ 2929
>XP_006715397
          Length = 2972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FNSMINQ 9
            FN M+NQ
Sbjct: 2832 FNQMLNQ 2838
>NP_001175
          Length = 2644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FNSMINQ 9
            FNS+IN+
Sbjct: 2341 FNSLINK 2347
>NP_001026849
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSF+ +IN
Sbjct: 100 PSFHDVIN 107
>NP_001180389
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSF+ +IN
Sbjct: 100 PSFHDVIN 107
>NP_001180390
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSF+ +IN
Sbjct: 100 PSFHDVIN 107
>NP_932346
          Length = 192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSFNSMIN 8
           PSF+ +IN
Sbjct: 107 PSFHDVIN 114
>NP_004280
          Length = 694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SFNSMINQ 9
           SFNSM+++
Sbjct: 561 SFNSMLSR 568
>NP_060485
          Length = 855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           PS NS++ Q
Sbjct: 112 PSLNSLVYQ 120
>NP_001171711
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSFNSMINQ 9
           PS NS++ Q
Sbjct: 112 PSLNSLVYQ 120
>NP_001273028
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SFNSMIN 8
           ++NSMIN
Sbjct: 334 TYNSMIN 340
>NP_060733
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    PSFNSMIN 8
            PS+  MIN
Sbjct: 1325 PSYRGMIN 1332
>NP_001013683
          Length = 414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SFNSMINQ 9
           SF+S INQ
Sbjct: 210 SFHSSINQ 217
>NP_005272
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SFNSMIN 8
           ++NSMIN
Sbjct: 287 TYNSMIN 293
>NP_005275
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SFNSMIN 8
           ++NSMIN
Sbjct: 319 TYNSMIN 325
>XP_006712103
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    PSFNSMIN 8
            PS+  MIN
Sbjct: 1065 PSYRGMIN 1072
>XP_006712102
          Length = 1313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    PSFNSMIN 8
            PS+  MIN
Sbjct: 1203 PSYRGMIN 1210
>NP_849189
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   SFNSMIN 8
           SFN+++N
Sbjct: 125 SFNALVN 131
>NP_775809
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   PSFNSMINQ 9
           PS++SM+++
Sbjct: 252 PSYDSMLSK 260
>NP_001273700
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PSFNSMI 7
            PS+NS+I
Sbjct: 2451 PSWNSLI 2457
>NP_115593
          Length = 2603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PSFNSMI 7
            PS+NS+I
Sbjct: 2564 PSWNSLI 2570
>NP_942592
          Length = 2352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PSFNSMI 7
            PS+NS+I
Sbjct: 2313 PSWNSLI 2319
>XP_005269574
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   SFNSMIN 8
           SFN+++N
Sbjct: 137 SFNALVN 143
>XP_006717681
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   SFNSMIN 8
           SFN+++N
Sbjct: 143 SFNALVN 149
>XP_006716575
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   PSFNSMINQ 9
           PS++SM+++
Sbjct: 252 PSYDSMLSK 260
>XP_005265728
          Length = 2351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PSFNSMI 7
            PS+NS+I
Sbjct: 2312 PSWNSLI 2318
>XP_005265724
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PSFNSMI 7
            PS+NS+I
Sbjct: 2563 PSWNSLI 2569
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.122    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,496
Number of extensions: 626
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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