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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055847                                                              17    4312
NP_001093869                                                           17    4312
XP_005266355                                                           17    4312
XP_005266354                                                           17    4312
XP_005266353                                                           17    4312
XP_005266352                                                           17    4312
XP_005262709                                                           17    4312
NP_919253                                                              16    5631
XP_005262550                                                           16    5631
NP_079460                                                              16    7355
XP_006724625                                                           16    7355
XP_006724624                                                           16    7355
XP_005272728                                                           16    7355
NP_056216                                                              15    9605
NP_689799                                                              15    9605
NP_001091886                                                           15    9605
XP_006719521                                                           15    9605
XP_006719520                                                           15    9605
XP_006719519                                                           15    9605
XP_005269025                                                           15    9605
XP_006719518                                                           15    9605
XP_006719517                                                           15    9605
XP_005271632                                                           15    9605
XP_005269639                                                           15    9605
XP_006717715                                                           15    9605
XP_006717714                                                           15    9605
XP_006717712                                                           15    9605
XP_005269635                                                           15    9605
XP_006717710                                                           15    9605
XP_006717709                                                           15    9605
XP_006717708                                                           15    9605

>NP_055847
          Length = 1447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   MSRLRLA 8
           MSRLRLA
Sbjct: 875 MSRLRLA 881



>NP_001093869
          Length = 1337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   MSRLRLA 8
           MSRLRLA
Sbjct: 885 MSRLRLA 891



>XP_005266355
          Length = 1448

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   MSRLRLA 8
           MSRLRLA
Sbjct: 875 MSRLRLA 881



>XP_005266354
          Length = 1411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   MSRLRLA 8
           MSRLRLA
Sbjct: 875 MSRLRLA 881



>XP_005266353
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   MSRLRLA 8
           MSRLRLA
Sbjct: 875 MSRLRLA 881



>XP_005266352
          Length = 1446

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   MSRLRLA 8
           MSRLRLA
Sbjct: 875 MSRLRLA 881



>XP_005262709
          Length = 1337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   MSRLRLA 8
           MSRLRLA
Sbjct: 885 MSRLRLA 891



>NP_919253
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PMSRLRLA 8
           PM+R+RL+
Sbjct: 673 PMARIRLS 680



>XP_005262550
          Length = 699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PMSRLRLA 8
           PM+R+RL+
Sbjct: 658 PMARIRLS 665



>NP_079460
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PMSRLRLAL 9
           P S L+LAL
Sbjct: 542 PFSNLKLAL 550



>XP_006724625
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PMSRLRLAL 9
           P S L+LAL
Sbjct: 346 PFSNLKLAL 354



>XP_006724624
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PMSRLRLAL 9
           P S L+LAL
Sbjct: 466 PFSNLKLAL 474



>XP_005272728
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PMSRLRLAL 9
           P S L+LAL
Sbjct: 542 PFSNLKLAL 550



>NP_056216
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 632 PLSRLKL 638



>NP_689799
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 827 ISKLRLAL 834



>NP_001091886
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 595 PLSRLKL 601



>XP_006719521
          Length = 944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 585 PLSRLKL 591



>XP_006719520
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 591 PLSRLKL 597



>XP_006719519
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 609 PLSRLKL 615



>XP_005269025
          Length = 974

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 615 PLSRLKL 621



>XP_006719518
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 622 PLSRLKL 628



>XP_006719517
          Length = 1005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PMSRLRL 7
           P+SRL+L
Sbjct: 646 PLSRLKL 652



>XP_005271632
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PMSRLR 6
           PMSR+R
Sbjct: 320 PMSRMR 325



>XP_005269639
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 770 ISKLRLAL 777



>XP_006717715
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 792 ISKLRLAL 799



>XP_006717714
          Length = 1665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856



>XP_006717712
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856



>XP_005269635
          Length = 1695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 827 ISKLRLAL 834



>XP_006717710
          Length = 1706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856



>XP_006717709
          Length = 1712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856



>XP_006717708
          Length = 1717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSRLRLAL 9
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.143    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 346,962
Number of extensions: 398
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)