Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              19     869
XP_006713721                                                           19     869
NP_001078896                                                           17    3301
NP_001078894                                                           17    3301
NP_001078897                                                           17    3301
NP_000478                                                              17    3301
NP_001078895                                                           17    3301
XP_006726390                                                           17    3301
XP_006726389                                                           17    3301
XP_006726388                                                           17    3301
XP_006726387                                                           17    3301
XP_006724477                                                           17    3301
XP_006710131                                                           17    3301
XP_006710130                                                           17    3301
XP_006710129                                                           17    3301
XP_006710128                                                           17    3301
NP_009098                                                              17    4312
NP_536355                                                              16    5631
NP_060019                                                              16    5631
NP_001229877                                                           16    5631
NP_056126                                                              16    7355
NP_009049                                                              16    7355
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
NP_997704                                                              16    7355
NP_006245                                                              16    7355
XP_006714558                                                           16    7355
XP_006713322                                                           16    7355
XP_006713321                                                           16    7355
XP_006713320                                                           16    7355
XP_005246888                                                           16    7355
XP_006712788                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
XP_005246482                                                           16    7355
XP_005246481                                                           16    7355
XP_006712450                                                           16    7355
XP_005246480                                                           16    7355
XP_006712449                                                           16    7355
XP_005246478                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_001269676                                                           15    9605
NP_001273708                                                           15    9605
NP_001269675                                                           15    9605
NP_057358                                                              15    9605
NP_115669                                                              15    9605
NP_612398                                                              15    9605
NP_001269674                                                           15    9605
NP_001273047                                                           15    9605
NP_001273048                                                           15    9605
NP_775104                                                              15    9605
NP_001003694                                                           15    9605
NP_060697                                                              15    9605
XP_005274213                                                           15    9605
XP_005274211                                                           15    9605
XP_005252438                                                           15    9605
XP_005252437                                                           15    9605
XP_005252325                                                           15    9605
XP_006717365                                                           15    9605
XP_005252324                                                           15    9605
XP_006714316                                                           15    9605
XP_005262730                                                           15    9605
XP_005262729                                                           15    9605
XP_005265509                                                           15    9605
XP_005265507                                                           15    9605
>NP_006209
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLSEIT QE
Sbjct: 539 PLSEITEQE 547
>XP_006713721
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLSEIT QE
Sbjct: 539 PLSEITEQE 547
>NP_001078896
          Length = 509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+TV E
Sbjct: 103 PLEEVTVAE 111
>NP_001078894
          Length = 509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+TV E
Sbjct: 103 PLEEVTVAE 111
>NP_001078897
          Length = 423

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PLSEITVQE 9
          PL E+TV E
Sbjct: 17 PLEEVTVAE 25
>NP_000478
          Length = 509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+TV E
Sbjct: 103 PLEEVTVAE 111
>NP_001078895
          Length = 509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+TV E
Sbjct: 103 PLEEVTVAE 111
>XP_006726390
          Length = 1353

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 684 PLSSITLQD 692
>XP_006726389
          Length = 1471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 802 PLSSITLQD 810
>XP_006726388
          Length = 1489

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 820 PLSSITLQD 828
>XP_006726387
          Length = 1497

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 868 PLSSITLQD 876
>XP_006724477
          Length = 488

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+TV E
Sbjct: 103 PLEEVTVAE 111
>XP_006710131
          Length = 1353

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 684 PLSSITLQD 692
>XP_006710130
          Length = 1471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 802 PLSSITLQD 810
>XP_006710129
          Length = 1489

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 820 PLSSITLQD 828
>XP_006710128
          Length = 1497

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLS IT+Q+
Sbjct: 868 PLSSITLQD 876
>NP_009098
          Length = 1325

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PLSEITVQ 8
           PLS +T+Q
Sbjct: 877 PLSNVTIQ 884
>NP_536355
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLSEITVQE 9
           PLSE+T +E
Sbjct: 96  PLSEMTREE 104
>NP_060019
          Length = 224

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           P  +ITVQE
Sbjct: 142 PQEQITVQE 150
>NP_001229877
          Length = 163

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PLSEITVQE 9
          P  +ITVQE
Sbjct: 81 PQEQITVQE 89
>NP_056126
          Length = 1896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++T+ E
Sbjct: 1545 PLEDVTISE 1553
>NP_009049
          Length = 3097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PLSEITVQ 8
            PLSE+T +
Sbjct: 2690 PLSEVTCE 2697
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++TV E
Sbjct: 4994 PLKDVTVPE 5002
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++TV E
Sbjct: 5119 PLKDVTVPE 5127
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     PLSEITVQE 9
             PL ++TV E
Sbjct: 12418 PLKDVTVPE 12426
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     PLSEITVQE 9
             PL ++TV E
Sbjct: 11491 PLKDVTVPE 11499
>NP_997704
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PLSEITV 7
          P+SE+TV
Sbjct: 80 PVSEVTV 86
>NP_006245
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PLSEITV 7
          P+SE+TV
Sbjct: 80 PVSEVTV 86
>XP_006714558
          Length = 2612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PLSEITVQ 8
            PLSE+T +
Sbjct: 2205 PLSEVTCE 2212
>XP_006713322
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PLSEITV 7
          P+SE+TV
Sbjct: 80 PVSEVTV 86
>XP_006713321
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PLSEITV 7
          P+SE+TV
Sbjct: 80 PVSEVTV 86
>XP_006713320
          Length = 692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLSEITV 7
           P+SE+TV
Sbjct: 96  PVSEVTV 102
>XP_005246888
          Length = 22663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL ++TV E
Sbjct: 731 PLKDVTVPE 739
>XP_006712788
          Length = 24022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++TV E
Sbjct: 2090 PLKDVTVPE 2098
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     PLSEITVQE 9
             PL ++TV E
Sbjct: 12046 PLKDVTVPE 12054
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     PLSEITVQE 9
             PL ++TV E
Sbjct: 13552 PLKDVTVPE 13560
>XP_005246482
          Length = 1724

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++T+ E
Sbjct: 1361 PLEDVTISE 1369
>XP_005246481
          Length = 1804

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++T+ E
Sbjct: 1453 PLEDVTISE 1461
>XP_006712450
          Length = 1816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++T+ E
Sbjct: 1453 PLEDVTISE 1461
>XP_005246480
          Length = 1816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++T+ E
Sbjct: 1453 PLEDVTISE 1461
>XP_006712449
          Length = 1908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++T+ E
Sbjct: 1545 PLEDVTISE 1553
>XP_005246478
          Length = 1908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++T+ E
Sbjct: 1545 PLEDVTISE 1553
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1     PLSEITVQE 9
             PL ++TV E
Sbjct: 14059 PLKDVTVPE 14067
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    PLSEITVQE 9
            PL ++TV E
Sbjct: 5186 PLKDVTVPE 5194
>NP_001269676
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+ +QE
Sbjct: 323 PLKELCLQE 331
>NP_001273708
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PLSE  V+E
Sbjct: 610 PLSESPVEE 618
>NP_001269675
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+ +QE
Sbjct: 586 PLKELCLQE 594
>NP_057358
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSEITVQE 9
           L E+TV+E
Sbjct: 139 LDEVTVEE 146
>NP_115669
          Length = 1013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PLSE  V+E
Sbjct: 632 PLSESPVEE 640
>NP_612398
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           P SEI +QE
Sbjct: 104 PRSEIPLQE 112
>NP_001269674
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+ +QE
Sbjct: 586 PLKELCLQE 594
>NP_001273047
          Length = 156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSEITVQE 9
          L EITVQ+
Sbjct: 9  LMEITVQQ 16
>NP_001273048
          Length = 156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSEITVQE 9
          L EITVQ+
Sbjct: 9  LMEITVQQ 16
>NP_775104
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+ +QE
Sbjct: 586 PLKELCLQE 594
>NP_001003694
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PLSEIT 6
           PLSE+T
Sbjct: 658 PLSEVT 663
>NP_060697
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSEITVQE 9
           LSE+ +QE
Sbjct: 787 LSEVKIQE 794
>XP_005274213
          Length = 156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSEITVQE 9
          L EITVQ+
Sbjct: 9  LMEITVQQ 16
>XP_005274211
          Length = 156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSEITVQE 9
          L EITVQ+
Sbjct: 9  LMEITVQQ 16
>XP_005252438
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+ +QE
Sbjct: 498 PLKELCLQE 506
>XP_005252437
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PL E+ +QE
Sbjct: 521 PLKELCLQE 529
>XP_005252325
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PLSE  V+E
Sbjct: 655 PLSESPVEE 663
>XP_006717365
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PLSE  V+E
Sbjct: 681 PLSESPVEE 689
>XP_005252324
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           PLSE  V+E
Sbjct: 695 PLSESPVEE 703
>XP_006714316
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSEITVQE 9
           LSE+ +QE
Sbjct: 712 LSEVKIQE 719
>XP_005262730
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           P SEI +QE
Sbjct: 104 PRSEIPLQE 112
>XP_005262729
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLSEITVQE 9
           P SEI +QE
Sbjct: 104 PRSEIPLQE 112
>XP_005265509
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PLSEIT 6
           PLSE+T
Sbjct: 658 PLSEVT 663
>XP_005265507
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PLSEIT 6
           PLSE+T
Sbjct: 658 PLSEVT 663
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.123    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 476,020
Number of extensions: 1021
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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