Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_597716                                                              17    3301
NP_057239                                                              17    3301
NP_612449                                                              17    3301
XP_005266705                                                           17    3301
XP_006722456                                                           17    3301
NP_001360                                                              17    4312
NP_001073866                                                           17    4312
NP_001487                                                              17    4312
XP_005248319                                                           17    4312
NP_079389                                                              16    5631
NP_001243390                                                           16    5631
NP_001037                                                              16    5631
NP_001273695                                                           16    5631
NP_001273693                                                           16    5631
NP_001273691                                                           16    5631
NP_001273690                                                           16    5631
NP_001273692                                                           16    5631
NP_001273694                                                           16    5631
NP_443100                                                              16    5631
NP_001662                                                              16    5631
NP_001139693                                                           16    5631
NP_001193594                                                           16    5631
XP_006719087                                                           16    5631
XP_005245671                                                           16    5631
NP_001025169                                                           16    7355
NP_001171809                                                           16    7355
NP_001098713                                                           16    7355
NP_065817                                                              16    7355
NP_001177636                                                           16    7355
NP_001844                                                              16    7355
NP_667340                                                              16    7355
NP_620063                                                              16    7355
NP_061888                                                              16    7355
NP_055918                                                              16    7355
XP_005263333                                                           16    7355
XP_006713158                                                           16    7355
XP_006713157                                                           16    7355
XP_006713156                                                           16    7355
XP_006713155                                                           16    7355
XP_006713154                                                           16    7355
XP_006713152                                                           16    7355
XP_006713151                                                           16    7355
NP_115961                                                              16    7355
NP_004804                                                              15    9605
NP_476515                                                              15    9605
NP_000301                                                              15    9605
NP_000735                                                              15    9605
NP_001184177                                                           15    9605
NP_001184175                                                           15    9605
NP_001268885                                                           15    9605
NP_057525                                                              15    9605
NP_061928                                                              15    9605
NP_008978                                                              15    9605
NP_001184176                                                           15    9605
NP_001184178                                                           15    9605
NP_114154                                                              15    9605
NP_002502                                                              15    9605
NP_060220                                                              15    9605
NP_872293                                                              15    9605
XP_006718924                                                           15    9605
XP_005251817                                                           15    9605
XP_006717052                                                           15    9605
XP_006715045                                                           15    9605
XP_005248884                                                           15    9605
XP_006715044                                                           15    9605
XP_006715043                                                           15    9605
XP_006715042                                                           15    9605
XP_005264415                                                           15    9605
XP_005264414                                                           15    9605
XP_005271065                                                           15    9605
XP_005271064                                                           15    9605
NP_849151                                                              15    9605
>NP_597716
          Length = 406

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  PIILLLSIG 9
          P++LLL++G
Sbjct: 22 PLLLLLALG 30
>NP_057239
          Length = 603

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  PIILLLSIG 9
          P++LLL++G
Sbjct: 24 PLLLLLALG 32
>NP_612449
          Length = 673

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  PIILLLSIG 9
          P++LLL++G
Sbjct: 10 PLLLLLALG 18
>XP_005266705
          Length = 406

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  PIILLLSIG 9
          P++LLL++G
Sbjct: 22 PLLLLLALG 30
>XP_006722456
          Length = 406

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  PIILLLSIG 9
          P++LLL++G
Sbjct: 22 PLLLLLALG 30
>NP_001360
          Length = 4624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PIILLLSIG 9
            P+I LLS+G
Sbjct: 4044 PLICLLSMG 4052
>NP_001073866
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P IL+L+IG
Sbjct: 190 PFILVLAIG 198
>NP_001487
          Length = 400

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   PIILLLSI 8
           P+ILLLS+
Sbjct: 392 PLILLLSL 399
>XP_005248319
          Length = 4609

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PIILLLSIG 9
            P+I LLS+G
Sbjct: 4029 PLICLLSMG 4037
>NP_079389
          Length = 662

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI  LLSIG
Sbjct: 501 PIFNLLSIG 509
>NP_001243390
          Length = 1196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           +ILLL+IG
Sbjct: 440 VILLLAIG 447
>NP_001037
          Length = 1212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           +ILLL+IG
Sbjct: 440 VILLLAIG 447
>NP_001273695
          Length = 447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI  LLSIG
Sbjct: 286 PIFNLLSIG 294
>NP_001273693
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI  LLSIG
Sbjct: 366 PIFNLLSIG 374
>NP_001273691
          Length = 635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI  LLSIG
Sbjct: 501 PIFNLLSIG 509
>NP_001273690
          Length = 662

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI  LLSIG
Sbjct: 501 PIFNLLSIG 509
>NP_001273692
          Length = 595

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI  LLSIG
Sbjct: 434 PIFNLLSIG 442
>NP_001273694
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI  LLSIG
Sbjct: 344 PIFNLLSIG 352
>NP_443100
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 14 PLLLLLMLG 22
>NP_001662
          Length = 291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P +LLLS+G
Sbjct: 39 PRLLLLSLG 47
>NP_001139693
          Length = 340

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  IILLLSIG 9
          +ILLLS+G
Sbjct: 10 VILLLSMG 17
>NP_001193594
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 14 PLLLLLMLG 22
>XP_006719087
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  IILLLSIG 9
          +ILLLS+G
Sbjct: 10 VILLLSMG 17
>XP_005245671
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 14 PLLLLLMLG 22
>NP_001025169
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P++LLL +G
Sbjct: 151 PLLLLLFLG 159
>NP_001171809
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  PIILLLSI 8
          P++LLL+I
Sbjct: 7  PVLLLLAI 14
>NP_001098713
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  PIILLLSI 8
          P++LLL+I
Sbjct: 7  PVLLLLAI 14
>NP_065817
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  PIILLLSI 8
          P++LLL+I
Sbjct: 7  PVLLLLAI 14
>NP_001177636
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>NP_001844
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 9  PLLLLLLLG 17
>NP_667340
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>NP_620063
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 38 PLLLLLLLG 46
>NP_061888
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P+IL LS+G
Sbjct: 15 PLILGLSLG 23
>NP_055918
          Length = 1925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 32 PLLLLLLLG 40
>XP_005263333
          Length = 358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P++LLL +G
Sbjct: 151 PLLLLLFLG 159
>XP_006713158
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713157
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713156
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713155
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713154
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713152
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713151
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IILLLSIG 9
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>NP_115961
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 10 PLLLLLLLG 18
>NP_004804
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P++ LLS+G
Sbjct: 228 PLLHLLSLG 236
>NP_476515
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P++ LLS+G
Sbjct: 228 PLLHLLSLG 236
>NP_000301
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P+I L+S+G
Sbjct: 132 PMINLISVG 140
>NP_000735
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PIILLLSIG 9
          P++LLL  G
Sbjct: 14 PLLLLLGTG 22
>NP_001184177
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 234 PILLLLLAG 242
>NP_001184175
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 257 PILLLLLAG 265
>NP_001268885
          Length = 3631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PIILLLSIG 9
          P++LLL  G
Sbjct: 46 PLLLLLGCG 54
>NP_057525
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PIILLLSI 8
           PII+ LSI
Sbjct: 946 PIIICLSI 953
>NP_061928
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 16 PLLLLLIMG 24
>NP_008978
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 257 PILLLLLAG 265
>NP_001184176
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 257 PILLLLLAG 265
>NP_001184178
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 215 PILLLLLAG 223
>NP_114154
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PIILLLSIG 9
          P++LLL  G
Sbjct: 8  PLLLLLCFG 16
>NP_002502
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           P+I L S+G
Sbjct: 120 PVIQLTSVG 128
>NP_060220
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  PIILLLSI 8
          P++LLL++
Sbjct: 4  PLVLLLAV 11
>NP_872293
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PIILLLS 7
          P++LLLS
Sbjct: 15 PLVLLLS 21
>XP_006718924
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PIILLLSIG 9
          P++LLL +G
Sbjct: 16 PLLLLLIMG 24
>XP_005251817
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PIILLLS 7
          P++LLLS
Sbjct: 15 PLVLLLS 21
>XP_006717052
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PIILLLS 7
          P++LLLS
Sbjct: 15 PLVLLLS 21
>XP_006715045
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 220 PILLLLLAG 228
>XP_005248884
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 257 PILLLLLAG 265
>XP_006715044
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 262 PILLLLLAG 270
>XP_006715043
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 262 PILLLLLAG 270
>XP_006715042
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PIILLLSIG 9
           PI+LLL  G
Sbjct: 262 PILLLLLAG 270
>XP_005264415
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PIILLLSI 8
           PII+ LSI
Sbjct: 881 PIIICLSI 888
>XP_005264414
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PIILLLSI 8
           PII+ LSI
Sbjct: 888 PIIICLSI 895
>XP_005271065
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P+I L+S+G
Sbjct: 132 PMINLISVG 140
>XP_005271064
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PIILLLSIG 9
           P+I L+S+G
Sbjct: 132 PMINLISVG 140
>NP_849151
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PIILLLSI 8
          PI+LLL +
Sbjct: 41 PILLLLQV 48
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.167    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 382,004
Number of extensions: 1011
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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