Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           20     299
NP_055903                                                              20     299
NP_001007227                                                           16    5631
NP_003554                                                              16    5631
NP_001007230                                                           16    5631
NP_001007228                                                           16    5631
NP_001007231                                                           16    5631
NP_001007229                                                           16    5631
NP_775822                                                              16    5631
XP_005257781                                                           16    5631
XP_005257780                                                           16    5631
XP_006717062                                                           16    5631
XP_006717061                                                           16    5631
XP_005251851                                                           16    5631
XP_005251850                                                           16    5631
NP_001073896                                                           16    7355
NP_075252                                                              16    7355
NP_998812                                                              16    7355
NP_002002                                                              16    7355
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
NP_001137307                                                           16    7355
NP_006156                                                              16    7355
NP_002381                                                              16    7355
NP_001073977                                                           16    7355
XP_005257430                                                           16    7355
XP_005271626                                                           16    7355
XP_005271625                                                           16    7355
XP_005271624                                                           16    7355
XP_005271623                                                           16    7355
XP_005271622                                                           16    7355
XP_006715665                                                           16    7355
XP_005265895                                                           16    7355
XP_005265894                                                           16    7355
XP_005263859                                                           16    7355
XP_005246888                                                           16    7355
XP_006712788                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_004159                                                              15    9605
NP_001148                                                              15    9605
NP_665875                                                              15    9605
NP_001265336                                                           15    9605
NP_001265337                                                           15    9605
NP_001265338                                                           15    9605
NP_665876                                                              15    9605
NP_036260                                                              15    9605
XP_006717877                                                           15    9605
XP_006717876                                                           15    9605
XP_005269799                                                           15    9605
XP_005269798                                                           15    9605
XP_005248388                                                           15    9605
XP_005248386                                                           15    9605
XP_006710516                                                           15    9605
NP_001129685                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NVSGQNRIG 9
           NVSGQ+RIG
Sbjct: 286 NVSGQDRIG 294
>NP_055903
          Length = 1723

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NVSGQNRIG 9
           NVSGQ+RIG
Sbjct: 286 NVSGQDRIG 294
>NP_001007227
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_003554
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007230
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007228
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007231
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007229
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_775822
          Length = 871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NVSGQNRIG 9
           +V+ QNR+G
Sbjct: 136 DVNAQNRLG 144
>XP_005257781
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>XP_005257780
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQN 6
           N+SGQN
Sbjct: 169 NISGQN 174
>XP_006717062
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  NVSGQNRIG 9
          +V+ QNR+G
Sbjct: 78 DVNAQNRLG 86
>XP_006717061
          Length = 872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NVSGQNRIG 9
           +V+ QNR+G
Sbjct: 136 DVNAQNRLG 144
>XP_005251851
          Length = 885

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NVSGQNRIG 9
           +V+ QNR+G
Sbjct: 136 DVNAQNRLG 144
>XP_005251850
          Length = 886

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NVSGQNRIG 9
           +V+ QNR+G
Sbjct: 136 DVNAQNRLG 144
>NP_001073896
          Length = 1577

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NVSGQNR 7
            N+SG+NR
Sbjct: 1495 NLSGKNR 1501
>NP_075252
          Length = 762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GQNRIG 9
           G+NRIG
Sbjct: 193 GENRIG 198
>NP_998812
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GQNRIG 9
           G+NRIG
Sbjct: 193 GENRIG 198
>NP_002002
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GQNRIG 9
           G+NRIG
Sbjct: 193 GENRIG 198
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VSGQNRIG 9
            V  QNRIG
Sbjct: 6768 VRAQNRIG 6775
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VSGQNRIG 9
            V  QNRIG
Sbjct: 6893 VRAQNRIG 6900
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     VSGQNRIG 9
             V  QNRIG
Sbjct: 14192 VRAQNRIG 14199
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     VSGQNRIG 9
             V  QNRIG
Sbjct: 13265 VRAQNRIG 13272
>NP_001137307
          Length = 1299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQNRI 8
           NV+GQN I
Sbjct: 912 NVTGQNII 919
>NP_006156
          Length = 1324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQNRI 8
           NV+GQN I
Sbjct: 937 NVTGQNII 944
>NP_002381
          Length = 769

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVSGQNRIG 9
           N+SG  R+G
Sbjct: 605 NISGAPRLG 613
>NP_001073977
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           SG+NR+G
Sbjct: 331 SGRNRMG 337
>XP_005257430
          Length = 774

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVSGQNRIG 9
           N+SG  R+G
Sbjct: 605 NISGAPRLG 613
>XP_005271626
          Length = 1294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NVSGQNRI 8
            NV+GQN I
Sbjct: 996  NVTGQNII 1003
>XP_005271625
          Length = 1311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQNRI 8
           NV+GQN I
Sbjct: 924 NVTGQNII 931
>XP_005271624
          Length = 1311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQNRI 8
           NV+GQN I
Sbjct: 924 NVTGQNII 931
>XP_005271623
          Length = 1371

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQNRI 8
           NV+GQN I
Sbjct: 984 NVTGQNII 991
>XP_005271622
          Length = 1383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NVSGQNRI 8
            NV+GQN I
Sbjct: 996  NVTGQNII 1003
>XP_006715665
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           SG+NR+G
Sbjct: 331 SGRNRMG 337
>XP_005265895
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GQNRIG 9
           G+NRIG
Sbjct: 193 GENRIG 198
>XP_005265894
          Length = 834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GQNRIG 9
           G+NRIG
Sbjct: 225 GENRIG 230
>XP_005263859
          Length = 1606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NVSGQNR 7
            N+SG+NR
Sbjct: 1524 NLSGKNR 1530
>XP_005246888
          Length = 22663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VSGQNRIG 9
            V  QNRIG
Sbjct: 2505 VRAQNRIG 2512
>XP_006712788
          Length = 24022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VSGQNRIG 9
            V  QNRIG
Sbjct: 3864 VRAQNRIG 3871
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     VSGQNRIG 9
             V  QNRIG
Sbjct: 13820 VRAQNRIG 13827
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     VSGQNRIG 9
             V  QNRIG
Sbjct: 15326 VRAQNRIG 15333
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2     VSGQNRIG 9
             V  QNRIG
Sbjct: 15833 VRAQNRIG 15840
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VSGQNRIG 9
            V  QNRIG
Sbjct: 6960 VRAQNRIG 6967
>NP_004159
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVSGQNRIG 9
           +V G NR+G
Sbjct: 445 SVHGANRLG 453
>NP_001148
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>NP_665875
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>NP_001265336
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>NP_001265337
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>NP_001265338
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 334 AGENRLG 340
>NP_665876
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>NP_036260
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   VSGQNRI 8
           +SG+NR+
Sbjct: 191 ISGRNRV 197
>XP_006717877
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>XP_006717876
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>XP_005269799
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 367 AGENRLG 373
>XP_005269798
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           +G+NR+G
Sbjct: 467 AGENRLG 473
>XP_005248388
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVSGQNRIG 9
           +V G NR+G
Sbjct: 445 SVHGANRLG 453
>XP_005248386
          Length = 668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVSGQNRIG 9
           +V G NR+G
Sbjct: 445 SVHGANRLG 453
>XP_006710516
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   VSGQNRI 8
           +SG+NR+
Sbjct: 191 ISGRNRV 197
>NP_001129685
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQNRIG 9
           SG+N++G
Sbjct: 149 SGKNKVG 155
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.132    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 567,184
Number of extensions: 942
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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