Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              21     229
XP_005266703                                                           21     229
NP_006370                                                              18    1482
XP_005250170                                                           18    1482
NP_149974                                                              18    1935
NP_001184033                                                           17    4312
NP_005924                                                              17    4312
NP_001243590                                                           17    4312
NP_001243589                                                           17    4312
XP_006723490                                                           17    4312
XP_006723488                                                           17    4312
XP_006723487                                                           17    4312
XP_006723486                                                           17    4312
XP_006718903                                                           17    4312
XP_006718902                                                           17    4312
NP_073580                                                              16    5631
NP_001161212                                                           16    5631
XP_005273285                                                           16    5631
NP_055848                                                              16    7355
NP_705833                                                              16    7355
XP_005251891                                                           16    7355
XP_005251890                                                           16    7355
XP_005251889                                                           16    7355
XP_005251888                                                           16    7355
XP_006717080                                                           16    7355
XP_005251887                                                           16    7355
XP_005251886                                                           16    7355
XP_005251885                                                           16    7355
XP_005251884                                                           16    7355
XP_005251883                                                           16    7355
XP_005251882                                                           16    7355
XP_005251881                                                           16    7355
XP_005251880                                                           16    7355
XP_005251879                                                           16    7355
XP_006717079                                                           16    7355
XP_005251878                                                           16    7355
XP_005251877                                                           16    7355
XP_005251876                                                           16    7355
XP_005251875                                                           16    7355
XP_005251874                                                           16    7355
XP_005251873                                                           16    7355
XP_005251872                                                           16    7355
XP_005247174                                                           16    7355
NP_055719                                                              15    9605
NP_689718                                                              15    9605
NP_620130                                                              15    9605
NP_001273700                                                           15    9605
NP_115593                                                              15    9605
NP_942592                                                              15    9605
XP_006724034                                                           15    9605
XP_006724033                                                           15    9605
XP_006724032                                                           15    9605
XP_006724031                                                           15    9605
XP_005260983                                                           15    9605
XP_006724030                                                           15    9605
XP_006719005                                                           15    9605
XP_005271789                                                           15    9605
XP_005271786                                                           15    9605
XP_005271785                                                           15    9605
XP_005271784                                                           15    9605
XP_005269686                                                           15    9605
XP_005265728                                                           15    9605
XP_005265724                                                           15    9605
>NP_443179
          Length = 2170

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    NVNNVSQDK 9
            NVNNVSQD+
Sbjct: 1368 NVNNVSQDQ 1376
>XP_005266703
          Length = 1501

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NVNNVSQDK 9
           NVNNVSQD+
Sbjct: 699 NVNNVSQDQ 707
>NP_006370
          Length = 751

 Score = 18.1 bits (35), Expect =  1482
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  NVNNVSQD 8
          N+NN+SQ+
Sbjct: 78 NINNISQE 85
>XP_005250170
          Length = 693

 Score = 18.1 bits (35), Expect =  1482
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  NVNNVSQD 8
          N+NN+SQ+
Sbjct: 20 NINNISQE 27
>NP_149974
          Length = 484

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           N+NN+S D+
Sbjct: 398 NLNNISSDR 406
>NP_001184033
          Length = 3972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    NNVSQDK 9
            NNVS DK
Sbjct: 2483 NNVSSDK 2489
>NP_005924
          Length = 3969

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    NNVSQDK 9
            NNVS DK
Sbjct: 2480 NNVSSDK 2486
>NP_001243590
          Length = 451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           NV+ VS+DK
Sbjct: 123 NVDQVSKDK 131
>NP_001243589
          Length = 451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           NV+ VS+DK
Sbjct: 123 NVDQVSKDK 131
>XP_006723490
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           NV+ VS+DK
Sbjct: 123 NVDQVSKDK 131
>XP_006723488
          Length = 451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           NV+ VS+DK
Sbjct: 123 NVDQVSKDK 131
>XP_006723487
          Length = 451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           NV+ VS+DK
Sbjct: 123 NVDQVSKDK 131
>XP_006723486
          Length = 451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           NV+ VS+DK
Sbjct: 123 NVDQVSKDK 131
>XP_006718903
          Length = 2673

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    NNVSQDK 9
            NNVS DK
Sbjct: 1184 NNVSSDK 1190
>XP_006718902
          Length = 2964

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    NNVSQDK 9
            NNVS DK
Sbjct: 1475 NNVSSDK 1481
>NP_073580
          Length = 369

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  NVNNVSQDK 9
          N+N +++DK
Sbjct: 73 NINKLTEDK 81
>NP_001161212
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           N+N +++DK
Sbjct: 132 NINKLTEDK 140
>XP_005273285
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           N+N +++DK
Sbjct: 132 NINKLTEDK 140
>NP_055848
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 508 VNNCAQDR 515
>NP_705833
          Length = 2970

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NVSQDK 9
           N+SQDK
Sbjct: 850 NISQDK 855
>XP_005251891
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 442 VNNCAQDR 449
>XP_005251890
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 442 VNNCAQDR 449
>XP_005251889
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 442 VNNCAQDR 449
>XP_005251888
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 447 VNNCAQDR 454
>XP_006717080
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 474 VNNCAQDR 481
>XP_005251887
          Length = 588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 474 VNNCAQDR 481
>XP_005251886
          Length = 592

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 479 VNNCAQDR 486
>XP_005251885
          Length = 606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 493 VNNCAQDR 500
>XP_005251884
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 493 VNNCAQDR 500
>XP_005251883
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 498 VNNCAQDR 505
>XP_005251882
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 498 VNNCAQDR 505
>XP_005251881
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 503 VNNCAQDR 510
>XP_005251880
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 503 VNNCAQDR 510
>XP_005251879
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 503 VNNCAQDR 510
>XP_006717079
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 507 VNNCAQDR 514
>XP_005251878
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 508 VNNCAQDR 515
>XP_005251877
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 508 VNNCAQDR 515
>XP_005251876
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 521 VNNCAQDR 528
>XP_005251875
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 526 VNNCAQDR 533
>XP_005251874
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 526 VNNCAQDR 533
>XP_005251873
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 526 VNNCAQDR 533
>XP_005251872
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VNNVSQDK 9
           VNN +QD+
Sbjct: 526 VNNCAQDR 533
>XP_005247174
          Length = 2679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NVSQDK 9
           N+SQDK
Sbjct: 559 NISQDK 564
>NP_055719
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           N+N++ +DK
Sbjct: 104 NLNDIFEDK 112
>NP_689718
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVNNVSQDK 9
           NV+ +SQ K
Sbjct: 99  NVSKISQSK 107
>NP_620130
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNVSQDK 9
           NNV +DK
Sbjct: 188 NNVDKDK 194
>NP_001273700
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NNVSQDK 9
            +NVSQD+
Sbjct: 2302 SNVSQDR 2308
>NP_115593
          Length = 2603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NNVSQDK 9
            +NVSQD+
Sbjct: 2415 SNVSQDR 2421
>NP_942592
          Length = 2352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NNVSQDK 9
            +NVSQD+
Sbjct: 2164 SNVSQDR 2170
>XP_006724034
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVNNVSQDK 9
           NV+ +SQ K
Sbjct: 99  NVSKISQSK 107
>XP_006724033
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVNNVSQDK 9
           NV+ +SQ K
Sbjct: 99  NVSKISQSK 107
>XP_006724032
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVNNVSQDK 9
           NV+ +SQ K
Sbjct: 99  NVSKISQSK 107
>XP_006724031
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVNNVSQDK 9
           NV+ +SQ K
Sbjct: 99  NVSKISQSK 107
>XP_005260983
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVNNVSQDK 9
           NV+ +SQ K
Sbjct: 99  NVSKISQSK 107
>XP_006724030
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVNNVSQDK 9
           NV+ +SQ K
Sbjct: 99  NVSKISQSK 107
>XP_006719005
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNVSQDK 9
           NNV +DK
Sbjct: 191 NNVDKDK 197
>XP_005271789
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNVSQDK 9
           NNV +DK
Sbjct: 191 NNVDKDK 197
>XP_005271786
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  NNVSQDK 9
          NNV +DK
Sbjct: 51 NNVDKDK 57
>XP_005271785
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  NNVSQDK 9
          NNV +DK
Sbjct: 51 NNVDKDK 57
>XP_005271784
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNVSQDK 9
           NNV +DK
Sbjct: 191 NNVDKDK 197
>XP_005269686
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NVNNVSQDK 9
           N+N++ +DK
Sbjct: 104 NLNDIFEDK 112
>XP_005265728
          Length = 2351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NNVSQDK 9
            +NVSQD+
Sbjct: 2163 SNVSQDR 2169
>XP_005265724
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NNVSQDK 9
            +NVSQD+
Sbjct: 2414 SNVSQDR 2420
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.111    0.275 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 470,564
Number of extensions: 750
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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