Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1135
XP_006718907                                                           18    1135
XP_006718906                                                           18    1135
XP_005271619                                                           18    1135
XP_005271618                                                           18    1135
NP_001185761                                                           16    5631
NP_001185763                                                           16    5631
NP_055459                                                              16    5631
NP_777576                                                              16    5631
XP_006726410                                                           16    5631
XP_006711719                                                           16    5631
XP_006711718                                                           16    5631
XP_006711717                                                           16    5631
XP_006711716                                                           16    5631
XP_006711715                                                           16    5631
XP_006711714                                                           16    5631
XP_006711713                                                           16    5631
XP_006711712                                                           16    5631
XP_006711711                                                           16    5631
XP_006711710                                                           16    5631
XP_006711709                                                           16    5631
XP_005277503                                                           16    5631
XP_005273038                                                           16    5631
XP_006711708                                                           16    5631
XP_005277500                                                           16    5631
XP_006711707                                                           16    5631
XP_005277499                                                           16    5631
XP_006711706                                                           16    5631
XP_006711705                                                           16    5631
XP_006711164                                                           16    5631
XP_006710143                                                           16    5631
XP_006710142                                                           16    5631
XP_006710141                                                           16    5631
NP_001074001                                                           16    5631
NP_787072                                                              16    5631
NP_001273961                                                           15    9605
NP_001273962                                                           15    9605
NP_038470                                                              15    9605
NP_001273960                                                           15    9605
NP_001009571                                                           15    9605
NP_060424                                                              15    9605
NP_001161412                                                           15    9605
NP_056121                                                              15    9605
NP_056041                                                              15    9605
NP_659448                                                              15    9605
NP_001230332                                                           15    9605
XP_006720933                                                           15    9605
XP_005255273                                                           15    9605
XP_005255272                                                           15    9605
XP_005255271                                                           15    9605
XP_005255270                                                           15    9605
XP_005255268                                                           15    9605
XP_005255267                                                           15    9605
XP_006717454                                                           15    9605
XP_005252443                                                           15    9605
XP_005252442                                                           15    9605
XP_005252441                                                           15    9605
XP_005250765                                                           15    9605
XP_005250764                                                           15    9605
XP_005250763                                                           15    9605
XP_005250762                                                           15    9605
XP_005250761                                                           15    9605
XP_005250760                                                           15    9605
XP_005250759                                                           15    9605
XP_005250758                                                           15    9605
XP_005250757                                                           15    9605
XP_005250756                                                           15    9605
XP_005250755                                                           15    9605
XP_005250754                                                           15    9605
XP_005250753                                                           15    9605
XP_005250752                                                           15    9605
XP_006710574                                                           15    9605
XP_005270746                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NSLKEVIIE 9
           +SLKEVIIE
Sbjct: 273 DSLKEVIIE 281
>XP_006718907
          Length = 3050

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NSLKEVIIE 9
           +SLKEVIIE
Sbjct: 273 DSLKEVIIE 281
>XP_006718906
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NSLKEVIIE 9
           +SLKEVIIE
Sbjct: 273 DSLKEVIIE 281
>XP_005271619
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NSLKEVIIE 9
           +SLKEVIIE
Sbjct: 273 DSLKEVIIE 281
>XP_005271618
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NSLKEVIIE 9
           +SLKEVIIE
Sbjct: 273 DSLKEVIIE 281
>NP_001185761
          Length = 2240

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1257 NSLKEMVL 1264
>NP_001185763
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1301 NSLKEMVL 1308
>NP_055459
          Length = 2346

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1301 NSLKEMVL 1308
>NP_777576
          Length = 1749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NS+KE++I
Sbjct: 1288 NSIKEMVI 1295
>XP_006726410
          Length = 2087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1104 NSLKEMVL 1111
>XP_006711719
          Length = 2302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1257 NSLKEMVL 1264
>XP_006711718
          Length = 1436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSLKEVII 8
           NSLKE+++
Sbjct: 308 NSLKEMVL 315
>XP_006711717
          Length = 2385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1257 NSLKEMVL 1264
>XP_006711716
          Length = 2411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1366 NSLKEMVL 1373
>XP_006711715
          Length = 2428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1300 NSLKEMVL 1307
>XP_006711714
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1301 NSLKEMVL 1308
>XP_006711713
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1304 NSLKEMVL 1311
>XP_006711712
          Length = 2473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_006711711
          Length = 2482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1354 NSLKEMVL 1361
>XP_006711710
          Length = 2494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1366 NSLKEMVL 1373
>XP_006711709
          Length = 2495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1367 NSLKEMVL 1374
>XP_005277503
          Length = 2498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_005273038
          Length = 2509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_006711708
          Length = 2512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_005277500
          Length = 2525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_006711707
          Length = 2553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_005277499
          Length = 2561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_006711706
          Length = 2591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1463 NSLKEMVL 1470
>XP_006711705
          Length = 2592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1464 NSLKEMVL 1471
>XP_006711164
          Length = 2087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSLKEVII 8
            NSLKE+++
Sbjct: 1104 NSLKEMVL 1111
>XP_006710143
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSLKEVII 8
           NSLKE+++
Sbjct: 143 NSLKEMVL 150
>XP_006710142
          Length = 671

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSLKEVII 8
           NSLKE+++
Sbjct: 252 NSLKEMVL 259
>XP_006710141
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSLKEVII 8
           NSLKE+++
Sbjct: 253 NSLKEMVL 260
>NP_001074001
          Length = 1100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NSLKEVIIE 9
           NS++E I+E
Sbjct: 294 NSIREAILE 302
>NP_787072
          Length = 725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NSLKEVIIE 9
           +S KE+IIE
Sbjct: 556 HSYKEIIIE 564
>NP_001273961
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SLKEVII 8
          SLKE++I
Sbjct: 27 SLKEIVI 33
>NP_001273962
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SLKEVII 8
          SLKE++I
Sbjct: 32 SLKEIVI 38
>NP_038470
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SLKEVII 8
          SLKE++I
Sbjct: 78 SLKEIVI 84
>NP_001273960
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SLKEVII 8
          SLKE++I
Sbjct: 78 SLKEIVI 84
>NP_001009571
          Length = 1255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1076 NSVKEII 1082
>NP_060424
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1117 NSVKEII 1123
>NP_001161412
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1121 NSVKEII 1127
>NP_056121
          Length = 2620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   NSLKEV 6
           NSLKEV
Sbjct: 405 NSLKEV 410
>NP_056041
          Length = 1053

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 331 NSLAEVIL 338
>NP_659448
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SLKEVIIE 9
          +LK+VI+E
Sbjct: 9  TLKDVIVE 16
>NP_001230332
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 329 NSLAEVIL 336
>XP_006720933
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 331 NSLAEVIL 338
>XP_005255273
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 331 NSLAEVIL 338
>XP_005255272
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 331 NSLAEVIL 338
>XP_005255271
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 331 NSLAEVIL 338
>XP_005255270
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 329 NSLAEVIL 336
>XP_005255268
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 331 NSLAEVIL 338
>XP_005255267
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSLKEVII 8
           NSL EVI+
Sbjct: 329 NSLAEVIL 336
>XP_006717454
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SLKEVIIE 9
          +LK+VI+E
Sbjct: 9  TLKDVIVE 16
>XP_005252443
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SLKEVIIE 9
          +LK+VI+E
Sbjct: 9  TLKDVIVE 16
>XP_005252442
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SLKEVIIE 9
          +LK+VI+E
Sbjct: 9  TLKDVIVE 16
>XP_005252441
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SLKEVIIE 9
          +LK+VI+E
Sbjct: 9  TLKDVIVE 16
>XP_005250765
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1071 NSVKEII 1077
>XP_005250764
          Length = 1258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1079 NSVKEII 1085
>XP_005250763
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1081 NSVKEII 1087
>XP_005250762
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1081 NSVKEII 1087
>XP_005250761
          Length = 1265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1086 NSVKEII 1092
>XP_005250760
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1089 NSVKEII 1095
>XP_005250759
          Length = 1293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1114 NSVKEII 1120
>XP_005250758
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1119 NSVKEII 1125
>XP_005250757
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1121 NSVKEII 1127
>XP_005250756
          Length = 1301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1122 NSVKEII 1128
>XP_005250755
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1124 NSVKEII 1130
>XP_005250754
          Length = 1305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1126 NSVKEII 1132
>XP_005250753
          Length = 1305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1126 NSVKEII 1132
>XP_005250752
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSLKEVI 7
            NS+KE+I
Sbjct: 1129 NSVKEII 1135
>XP_006710574
          Length = 2445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   NSLKEV 6
           NSLKEV
Sbjct: 230 NSLKEV 235
>XP_005270746
          Length = 2443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   NSLKEV 6
           NSLKEV
Sbjct: 230 NSLKEV 235
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.131    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 438,214
Number of extensions: 736
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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