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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245202                                                           20     509
NP_001245200                                                           20     509
NP_001161091                                                           20     509
NP_000240                                                              20     509
NP_001161090                                                           20     509
NP_001161089                                                           20     509
NP_001245203                                                           20     509
XP_005265221                                                           20     509
XP_005265220                                                           20     509
NP_060876                                                              17    2528
NP_078831                                                              17    2528
NP_036294                                                              17    2528
NP_065228                                                              17    4312
NP_001164278                                                           17    4312
XP_006715676                                                           17    4312
NP_005110                                                              16    5631
NP_002449                                                              16    7355
NP_001092002                                                           16    7355
NP_001092001                                                           16    7355
NP_006096                                                              16    7355
XP_005268628                                                           16    7355
XP_005268627                                                           16    7355
XP_005268626                                                           16    7355
NP_003189                                                              16    7355
NP_065988                                                              15    9605
NP_277047                                                              15    9605
XP_005259798                                                           15    9605
XP_006722711                                                           15    9605
XP_005267986                                                           15    9605
NP_001290                                                              15    9605

>NP_001245202
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NHSLVESTS 9
          NH LVESTS
Sbjct: 22 NHRLVESTS 30



>NP_001245200
          Length = 687

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NHSLVESTS 9
           NH LVESTS
Sbjct: 263 NHRLVESTS 271



>NP_001161091
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NHSLVESTS 9
          NH LVESTS
Sbjct: 22 NHRLVESTS 30



>NP_000240
          Length = 756

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NHSLVESTS 9
           NH LVESTS
Sbjct: 263 NHRLVESTS 271



>NP_001161090
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NHSLVESTS 9
          NH LVESTS
Sbjct: 22 NHRLVESTS 30



>NP_001161089
          Length = 658

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NHSLVESTS 9
           NH LVESTS
Sbjct: 165 NHRLVESTS 173



>NP_001245203
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NHSLVESTS 9
          NH LVESTS
Sbjct: 22 NHRLVESTS 30



>XP_005265221
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NHSLVESTS 9
          NH LVESTS
Sbjct: 22 NHRLVESTS 30



>XP_005265220
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NHSLVESTS 9
          NH LVESTS
Sbjct: 22 NHRLVESTS 30



>NP_060876
          Length = 5412

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NHSLVESTS 9
           NHS + STS
Sbjct: 617 NHSTIHSTS 625



>NP_078831
          Length = 533

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   HSLVESTS 9
           HS+VEST+
Sbjct: 249 HSMVESTA 256



>NP_036294
          Length = 539

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   HSLVESTS 9
           HS+VEST+
Sbjct: 255 HSMVESTA 262



>NP_065228
          Length = 284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  NHSLVE 6
          NHSLVE
Sbjct: 73 NHSLVE 78



>NP_001164278
          Length = 284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  NHSLVE 6
          NHSLVE
Sbjct: 73 NHSLVE 78



>XP_006715676
          Length = 284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  NHSLVE 6
          NHSLVE
Sbjct: 73 NHSLVE 78



>NP_005110
          Length = 955

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NHSLVEST 8
           NHS VES+
Sbjct: 165 NHSRVESS 172



>NP_002449
          Length = 5762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   HSLVESTS 9
           H+LV+ST+
Sbjct: 275 HALVDSTA 282



>NP_001092002
          Length = 881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NHSLVES 7
           NH+LVE+
Sbjct: 787 NHTLVEN 793



>NP_001092001
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NHSLVES 7
           NH+LVE+
Sbjct: 829 NHTLVEN 835



>NP_006096
          Length = 881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NHSLVES 7
           NH+LVE+
Sbjct: 787 NHTLVEN 793



>XP_005268628
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NHSLVES 7
           NH+LVE+
Sbjct: 401 NHTLVEN 407



>XP_005268627
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NHSLVES 7
           NH+LVE+
Sbjct: 685 NHTLVEN 691



>XP_005268626
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NHSLVES 7
           NH+LVE+
Sbjct: 685 NHTLVEN 691



>NP_003189
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   NHSLVEST 8
           NH L+E T
Sbjct: 622 NHVLIEET 629



>NP_065988
          Length = 2048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NHSLVESTS 9
            NH+ V+ST+
Sbjct: 1752 NHNEVQSTT 1760



>NP_277047
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NHSLVES 7
           NHS +ES
Sbjct: 356 NHSSIES 362



>XP_005259798
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  NHSLVEST 8
          NH+ V+ST
Sbjct: 66 NHTQVQST 73



>XP_006722711
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NHSLVEST 8
           NH+ V+ST
Sbjct: 116 NHTQVQST 123



>XP_005267986
          Length = 2022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NHSLVESTS 9
            NH+ V+ST+
Sbjct: 1726 NHNEVQSTT 1734



>NP_001290
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NHSLVEST 8
           NH+ V+ST
Sbjct: 116 NHTQVQST 123



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288    0.101    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,212
Number of extensions: 625
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)