Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245202                                                           20     509
NP_001245200                                                           20     509
NP_001161091                                                           20     509
NP_000240                                                              20     509
NP_001161090                                                           20     509
NP_001161089                                                           20     509
NP_001245203                                                           20     509
XP_005265223                                                           20     509
XP_005265221                                                           20     509
XP_005265220                                                           20     509
XP_005265218                                                           20     509
NP_115896                                                              17    3301
NP_001171672                                                           17    3301
XP_006715291                                                           17    3301
NP_006148                                                              17    4312
NP_963845                                                              17    4312
NP_001275643                                                           17    4312
NP_001275642                                                           17    4312
NP_149160                                                              16    5631
NP_149159                                                              16    5631
NP_068707                                                              16    5631
NP_001243233                                                           16    5631
NP_001243232                                                           16    5631
NP_899205                                                              16    5631
NP_899204                                                              16    5631
XP_005264243                                                           16    5631
XP_006712025                                                           16    5631
XP_006712024                                                           16    5631
XP_005264241                                                           16    5631
XP_005264240                                                           16    5631
XP_005264239                                                           16    5631
XP_006712023                                                           16    5631
NP_071331                                                              16    7355
NP_937983                                                              16    7355
NP_001180305                                                           16    7355
NP_001038188                                                           16    7355
NP_004375                                                              16    7355
NP_001257501                                                           16    7355
NP_001277141                                                           16    7355
NP_114151                                                              16    7355
NP_001026982                                                           16    7355
NP_001310                                                              16    7355
XP_005259557                                                           16    7355
XP_005259556                                                           16    7355
XP_005259555                                                           16    7355
XP_005271953                                                           16    7355
XP_005271952                                                           16    7355
XP_005271951                                                           16    7355
XP_005271950                                                           16    7355
XP_005271949                                                           16    7355
XP_005271948                                                           16    7355
NP_872387                                                              15    9605
NP_001138762                                                           15    9605
NP_001265432                                                           15    9605
NP_938018                                                              15    9605
NP_689926                                                              15    9605
NP_001094092                                                           15    9605
NP_060411                                                              15    9605
NP_003804                                                              15    9605
NP_003610                                                              15    9605
XP_005257544                                                           15    9605
XP_005263375                                                           15    9605
XP_005245160                                                           15    9605
>NP_001245202
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 329 NFGVLRLS 336
>NP_001245200
          Length = 687

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 570 NFGVLRLS 577
>NP_001161091
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 329 NFGVLRLS 336
>NP_000240
          Length = 756

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 570 NFGVLRLS 577
>NP_001161090
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 329 NFGVLRLS 336
>NP_001161089
          Length = 658

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 472 NFGVLRLS 479
>NP_001245203
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 329 NFGVLRLS 336
>XP_005265223
          Length = 415

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 229 NFGVLRLS 236
>XP_005265221
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 329 NFGVLRLS 336
>XP_005265220
          Length = 515

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 329 NFGVLRLS 336
>XP_005265218
          Length = 687

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   NFGVLRLS 8
           NFGVLRLS
Sbjct: 501 NFGVLRLS 508
>NP_115896
          Length = 809

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FGVLRLSG 9
           FGVL LSG
Sbjct: 461 FGVLLLSG 468
>NP_001171672
          Length = 809

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FGVLRLSG 9
           FGVL LSG
Sbjct: 461 FGVLLLSG 468
>XP_006715291
          Length = 558

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   FGVLRLSG 9
           FGVL LSG
Sbjct: 210 FGVLLLSG 217
>NP_006148
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NFGVLRLSG 9
           ++GV RLSG
Sbjct: 770 SYGVSRLSG 778
>NP_963845
          Length = 763

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NFGVLRLSG 9
           ++GV RLSG
Sbjct: 723 SYGVSRLSG 731
>NP_001275643
          Length = 753

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NFGVLRLSG 9
           ++GV RLSG
Sbjct: 713 SYGVSRLSG 721
>NP_001275642
          Length = 838

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NFGVLRLSG 9
           ++GV RLSG
Sbjct: 798 SYGVSRLSG 806
>NP_149160
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>NP_149159
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>NP_068707
          Length = 627

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>NP_001243233
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>NP_001243232
          Length = 620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>NP_899205
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>NP_899204
          Length = 609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>XP_005264243
          Length = 318

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>XP_006712025
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>XP_006712024
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>XP_005264241
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>XP_005264240
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>XP_005264239
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>XP_006712023
          Length = 624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NFGVLRLS 8
          NF V+RLS
Sbjct: 26 NFDVIRLS 33
>NP_071331
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 54 NFGELRL 60
>NP_937983
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FGVLRL 7
           FGVLRL
Sbjct: 975 FGVLRL 980
>NP_001180305
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FGVLRL 7
           FGVLRL
Sbjct: 912 FGVLRL 917
>NP_001038188
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>NP_004375
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>NP_001257501
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>NP_001277141
          Length = 393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FGVLRL 7
           FGVLRL
Sbjct: 298 FGVLRL 303
>NP_114151
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FGVLRL 7
           FGVLRL
Sbjct: 260 FGVLRL 265
>NP_001026982
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>NP_001310
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 56 NFGELRL 62
>XP_005259557
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 56 NFGELRL 62
>XP_005259556
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 56 NFGELRL 62
>XP_005259555
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 56 NFGELRL 62
>XP_005271953
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>XP_005271952
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>XP_005271951
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>XP_005271950
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>XP_005271949
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>XP_005271948
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NFGVLRL 7
          NFG LRL
Sbjct: 53 NFGELRL 59
>NP_872387
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  NFGVLRLSG 9
          NF +L +SG
Sbjct: 3  NFSLLSISG 11
>NP_001138762
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   FGVLRLSG 9
           FG LR+ G
Sbjct: 289 FGALRIPG 296
>NP_001265432
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  FGVLRLS 8
          FG LRLS
Sbjct: 4  FGFLRLS 10
>NP_938018
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   FGVLRLSG 9
           FG LR+ G
Sbjct: 289 FGALRIPG 296
>NP_689926
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  FGVLRLS 8
          FG LRLS
Sbjct: 4  FGFLRLS 10
>NP_001094092
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NFGVLRLSG 9
           NF ++RL G
Sbjct: 528 NFSLMRLLG 536
>NP_060411
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NFGVLRLSG 9
           NF ++RL G
Sbjct: 528 NFSLMRLLG 536
>NP_003804
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLRLSG 9
           GVL++SG
Sbjct: 134 GVLKISG 140
>NP_003610
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLRLSG 9
           GV+RL+G
Sbjct: 385 GVIRLAG 391
>XP_005257544
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NFGVLRLSG 9
           NF ++RL G
Sbjct: 528 NFSLMRLLG 536
>XP_005263375
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLRLSG 9
           GV+RL+G
Sbjct: 385 GVIRLAG 391
>XP_005245160
          Length = 223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  NFGVLRLSG 9
          NF +L +SG
Sbjct: 3  NFSLLSISG 11
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.153    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 444,370
Number of extensions: 741
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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