Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055847                                                              17    4312
NP_001093869                                                           17    4312
XP_005266355                                                           17    4312
XP_005266354                                                           17    4312
XP_005266353                                                           17    4312
XP_005266352                                                           17    4312
XP_005262709                                                           17    4312
NP_689799                                                              15    9605
XP_005269639                                                           15    9605
XP_006717715                                                           15    9605
XP_006717714                                                           15    9605
XP_006717712                                                           15    9605
XP_005269635                                                           15    9605
XP_006717710                                                           15    9605
XP_006717709                                                           15    9605
XP_006717708                                                           15    9605
>NP_055847
          Length = 1447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   MSRLRLA 7
           MSRLRLA
Sbjct: 875 MSRLRLA 881
>NP_001093869
          Length = 1337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   MSRLRLA 7
           MSRLRLA
Sbjct: 885 MSRLRLA 891
>XP_005266355
          Length = 1448

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   MSRLRLA 7
           MSRLRLA
Sbjct: 875 MSRLRLA 881
>XP_005266354
          Length = 1411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   MSRLRLA 7
           MSRLRLA
Sbjct: 875 MSRLRLA 881
>XP_005266353
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   MSRLRLA 7
           MSRLRLA
Sbjct: 875 MSRLRLA 881
>XP_005266352
          Length = 1446

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   MSRLRLA 7
           MSRLRLA
Sbjct: 875 MSRLRLA 881
>XP_005262709
          Length = 1337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   MSRLRLA 7
           MSRLRLA
Sbjct: 885 MSRLRLA 891
>NP_689799
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 827 ISKLRLAL 834
>XP_005269639
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 770 ISKLRLAL 777
>XP_006717715
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 792 ISKLRLAL 799
>XP_006717714
          Length = 1665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856
>XP_006717712
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856
>XP_005269635
          Length = 1695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 827 ISKLRLAL 834
>XP_006717710
          Length = 1706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856
>XP_006717709
          Length = 1712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856
>XP_006717708
          Length = 1717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MSRLRLAL 8
           +S+LRLAL
Sbjct: 849 ISKLRLAL 856
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.138    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 271,841
Number of extensions: 212
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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