Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1482
NP_001263689                                                           18    1482
NP_001119584                                                           18    1482
NP_001119586                                                           18    1482
NP_001263625                                                           18    1482
NP_001119590                                                           18    1482
NP_001263690                                                           18    1482
NP_001119585                                                           18    1482
NP_001263624                                                           18    1482
NP_001119588                                                           18    1482
NP_001119587                                                           18    1482
NP_001119589                                                           18    1482
NP_001263627                                                           18    1482
NP_001263628                                                           18    1482
NP_001263626                                                           18    1482
NP_057063                                                              17    4312
NP_004821                                                              17    4312
NP_001257451                                                           17    4312
NP_001257450                                                           17    4312
XP_006717307                                                           17    4312
XP_006717306                                                           17    4312
XP_006717305                                                           17    4312
XP_005266153                                                           17    4312
XP_006717304                                                           17    4312
XP_006715675                                                           17    4312
XP_005267280                                                           17    4312
NP_003077                                                              17    4312
NP_005952                                                              15    9605
NP_005579                                                              15    9605
NP_004450                                                              15    9605
NP_872579                                                              15    9605
XP_005257219                                                           15    9605
XP_005257218                                                           15    9605
XP_005257217                                                           15    9605
XP_005257216                                                           15    9605
XP_005257215                                                           15    9605
XP_005257214                                                           15    9605
XP_005257213                                                           15    9605
XP_005257212                                                           15    9605
XP_006721834                                                           15    9605
XP_005257211                                                           15    9605
XP_005257210                                                           15    9605
XP_005257209                                                           15    9605
XP_005257208                                                           15    9605
XP_006721833                                                           15    9605
XP_005257207                                                           15    9605
NP_835228                                                              15    9605
>NP_000537
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 246 MNRRPILTI 254
>NP_001263689
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 207 MNRRPILTI 215
>NP_001119584
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 246 MNRRPILTI 254
>NP_001119586
          Length = 341

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 246 MNRRPILTI 254
>NP_001263625
          Length = 302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 207 MNRRPILTI 215
>NP_001119590
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 207 MNRRPILTI 215
>NP_001263690
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 207 MNRRPILTI 215
>NP_001119585
          Length = 346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 246 MNRRPILTI 254
>NP_001263624
          Length = 307

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 207 MNRRPILTI 215
>NP_001119588
          Length = 209

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 114 MNRRPILTI 122
>NP_001119587
          Length = 261

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 114 MNRRPILTI 122
>NP_001119589
          Length = 214

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           MNRR ILTI
Sbjct: 114 MNRRPILTI 122
>NP_001263627
          Length = 182

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  MNRRLILTI 9
          MNRR ILTI
Sbjct: 87 MNRRPILTI 95
>NP_001263628
          Length = 187

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  MNRRLILTI 9
          MNRR ILTI
Sbjct: 87 MNRRPILTI 95
>NP_001263626
          Length = 234

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  MNRRLILTI 9
          MNRR ILTI
Sbjct: 87 MNRRPILTI 95
>NP_057063
          Length = 1365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NR LILT+
Sbjct: 689 LNRALILTL 697
>NP_004821
          Length = 1368

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NR LILT+
Sbjct: 683 LNRALILTL 691
>NP_001257451
          Length = 1364

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NR LILT+
Sbjct: 683 LNRALILTL 691
>NP_001257450
          Length = 1359

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NR LILT+
Sbjct: 683 LNRALILTL 691
>XP_006717307
          Length = 873

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NRRL+L +
Sbjct: 144 LNRRLLLAV 152
>XP_006717306
          Length = 1441

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NRRL+L +
Sbjct: 712 LNRRLLLAV 720
>XP_006717305
          Length = 1469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NRRL+L +
Sbjct: 740 LNRRLLLAV 748
>XP_005266153
          Length = 1469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NRRL+L +
Sbjct: 740 LNRRLLLAV 748
>XP_006717304
          Length = 1469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NRRL+L +
Sbjct: 740 LNRRLLLAV 748
>XP_006715675
          Length = 747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NR LILT+
Sbjct: 689 LNRALILTL 697
>XP_005267280
          Length = 1374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NR LILT+
Sbjct: 689 LNRALILTL 697
>NP_003077
          Length = 1469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNRRLILTI 9
           +NRRL+L +
Sbjct: 740 LNRRLLLAV 748
>NP_005952
          Length = 2439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RRLILTI 9
            RRL+LT+
Sbjct: 2418 RRLVLTL 2424
>NP_005579
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NRRLILTI 9
           NR++I+TI
Sbjct: 503 NRQVIITI 510
>NP_004450
          Length = 2903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>NP_872579
          Length = 2920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257219
          Length = 2038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257218
          Length = 2957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257217
          Length = 2961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257216
          Length = 3015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257215
          Length = 3032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257214
          Length = 3094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257213
          Length = 3095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257212
          Length = 3095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_006721834
          Length = 3100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257211
          Length = 3100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257210
          Length = 3104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257209
          Length = 3148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257208
          Length = 3157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_006721833
          Length = 3158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>XP_005257207
          Length = 3158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNRRLIL 7
           +NRRLI+
Sbjct: 473 LNRRLII 479
>NP_835228
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   MNRRLILT 8
           MNR L+LT
Sbjct: 120 MNRVLLLT 127
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.155    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 401,064
Number of extensions: 599
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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