Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_009052                                                              20     390
NP_001243576                                                           20     390
NP_005684                                                              19     869
NP_001238863                                                           19     869
NP_001123573                                                           19     869
NP_001238864                                                           19     869
NP_001123574                                                           19     869
XP_005252775                                                           19     869
XP_006718179                                                           19     869
XP_005252773                                                           19     869
XP_005252772                                                           19     869
XP_005252770                                                           19     869
XP_005252767                                                           19     869
XP_005252766                                                           19     869
XP_006718178                                                           19     869
XP_006718177                                                           19     869
XP_005252764                                                           19     869
XP_005252763                                                           19     869
XP_006718176                                                           19     869
XP_006718175                                                           19     869
XP_005252762                                                           19     869
NP_938073                                                              16    7355
XP_005244801                                                           16    7355
XP_006710664                                                           16    7355
XP_006710663                                                           16    7355
>NP_009052
          Length = 461

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+TARRY
Sbjct: 312 MLLETARRY 320
>NP_001243576
          Length = 364

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+TARRY
Sbjct: 215 MLLETARRY 223
>NP_005684
          Length = 447

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 298 MLLETSRRY 306
>NP_001238863
          Length = 453

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 304 MLLETSRRY 312
>NP_001123573
          Length = 387

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 238 MLLETSRRY 246
>NP_001238864
          Length = 453

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 304 MLLETSRRY 312
>NP_001123574
          Length = 402

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 253 MLLETSRRY 261
>XP_005252775
          Length = 253

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 104 MLLETSRRY 112
>XP_006718179
          Length = 402

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 253 MLLETSRRY 261
>XP_005252773
          Length = 313

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 164 MLLETSRRY 172
>XP_005252772
          Length = 358

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 209 MLLETSRRY 217
>XP_005252770
          Length = 387

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 238 MLLETSRRY 246
>XP_005252767
          Length = 402

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 253 MLLETSRRY 261
>XP_005252766
          Length = 402

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 253 MLLETSRRY 261
>XP_006718178
          Length = 402

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 253 MLLETSRRY 261
>XP_006718177
          Length = 447

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 298 MLLETSRRY 306
>XP_005252764
          Length = 447

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 298 MLLETSRRY 306
>XP_005252763
          Length = 447

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 298 MLLETSRRY 306
>XP_006718176
          Length = 447

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 298 MLLETSRRY 306
>XP_006718175
          Length = 447

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 298 MLLETSRRY 306
>XP_005252762
          Length = 447

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   MLLKTARRY 9
           MLL+T+RRY
Sbjct: 298 MLLETSRRY 306
>NP_938073
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLKTARRY 9
           LLK A RY
Sbjct: 209 LLKAAHRY 216
>XP_005244801
          Length = 613

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLKTARRY 9
           LLK A RY
Sbjct: 157 LLKAAHRY 164
>XP_006710664
          Length = 463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLKTARRY 9
           LLK A RY
Sbjct: 209 LLKAAHRY 216
>XP_006710663
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLKTARRY 9
           LLK A RY
Sbjct: 209 LLKAAHRY 216
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.140    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 317,746
Number of extensions: 494
Number of successful extensions: 25
Number of sequences better than 10000.0: 25
Number of HSP's gapped: 25
Number of HSP's successfully gapped: 25
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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