Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1482
XP_005271621                                                           18    1482
XP_006718907                                                           18    1482
XP_006718906                                                           18    1482
XP_005271619                                                           18    1482
XP_005271618                                                           18    1482
XP_006724219                                                           17    3301
XP_006724218                                                           17    3301
XP_006724217                                                           17    3301
NP_689726                                                              17    3301
NP_060899                                                              17    4312
XP_006725524                                                           17    4312
XP_006725523                                                           17    4312
XP_005276828                                                           17    4312
XP_006726279                                                           17    4312
XP_006714722                                                           17    4312
XP_006714721                                                           17    4312
NP_038477                                                              16    5631
XP_005268661                                                           16    5631
XP_005268660                                                           16    5631
XP_005268659                                                           16    5631
XP_005268657                                                           16    5631
XP_006719270                                                           16    5631
XP_005268656                                                           16    5631
XP_005268654                                                           16    5631
XP_005268653                                                           16    5631
NP_116265                                                              16    7355
NP_079199                                                              16    7355
XP_005268211                                                           16    7355
XP_005268018                                                           16    7355
XP_005265051                                                           16    7355
NP_001092872                                                           16    7355
NP_060783                                                              15    9605
NP_001010904                                                           15    9605
NP_001129975                                                           15    9605
NP_001243064                                                           15    9605
NP_940969                                                              15    9605
NP_004515                                                              15    9605
NP_001026973                                                           15    9605
NP_001307                                                              15    9605
XP_006721961                                                           15    9605
XP_006721960                                                           15    9605
XP_005265966                                                           15    9605
XP_006713297                                                           15    9605
XP_006713296                                                           15    9605
XP_006713295                                                           15    9605
XP_005265345                                                           15    9605
XP_006713294                                                           15    9605
XP_006713293                                                           15    9605
XP_006713292                                                           15    9605
XP_006713291                                                           15    9605
XP_006713290                                                           15    9605
XP_006713289                                                           15    9605
XP_005265340                                                           15    9605
XP_005265339                                                           15    9605
XP_006713288                                                           15    9605
XP_005265337                                                           15    9605
XP_005265336                                                           15    9605
XP_006713287                                                           15    9605
XP_006713286                                                           15    9605
XP_005265332                                                           15    9605
XP_006713285                                                           15    9605
XP_006713284                                                           15    9605
XP_006713283                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVLEKIL+S
Sbjct: 606 LVLEKILVS 614
>XP_005271621
          Length = 2708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVLEKIL+S
Sbjct: 258 LVLEKILVS 266
>XP_006718907
          Length = 3050

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVLEKIL+S
Sbjct: 606 LVLEKILVS 614
>XP_006718906
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVLEKIL+S
Sbjct: 606 LVLEKILVS 614
>XP_005271619
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVLEKIL+S
Sbjct: 606 LVLEKILVS 614
>XP_005271618
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVLEKIL+S
Sbjct: 606 LVLEKILVS 614
>XP_006724219
          Length = 1157

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVL+K+LLS
Sbjct: 284 LVLKKLLLS 292
>XP_006724218
          Length = 1200

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVL+K+LLS
Sbjct: 284 LVLKKLLLS 292
>XP_006724217
          Length = 1235

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVL+K+LLS
Sbjct: 284 LVLKKLLLS 292
>NP_689726
          Length = 1274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVL+K+LLS
Sbjct: 284 LVLKKLLLS 292
>NP_060899
          Length = 2624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           VLEKIL+S
Sbjct: 833 VLEKILVS 840
>XP_006725524
          Length = 2584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           VLEKIL+S
Sbjct: 833 VLEKILVS 840
>XP_006725523
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           VLEKIL+S
Sbjct: 833 VLEKILVS 840
>XP_005276828
          Length = 2584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           VLEKIL+S
Sbjct: 833 VLEKILVS 840
>XP_006726279
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           VLEKIL+S
Sbjct: 833 VLEKILVS 840
>XP_006714722
          Length = 2584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           VLEKIL+S
Sbjct: 833 VLEKILVS 840
>XP_006714721
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           VLEKIL+S
Sbjct: 833 VLEKILVS 840
>NP_038477
          Length = 1905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1612 VVLEKALLS 1620
>XP_005268661
          Length = 1657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1364 VVLEKALLS 1372
>XP_005268660
          Length = 1875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1582 VVLEKALLS 1590
>XP_005268659
          Length = 1894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1601 VVLEKALLS 1609
>XP_005268657
          Length = 1903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1610 VVLEKALLS 1618
>XP_006719270
          Length = 1903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1610 VVLEKALLS 1618
>XP_005268656
          Length = 1903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1610 VVLEKALLS 1618
>XP_005268654
          Length = 1923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1631 VVLEKALLS 1639
>XP_005268653
          Length = 1924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LVLEKILLS 9
            +VLEK LLS
Sbjct: 1631 VVLEKALLS 1639
>NP_116265
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LVLEKIL 7
           L+LEKIL
Sbjct: 409 LILEKIL 415
>NP_079199
          Length = 1887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVLEKILLS 9
           L+LE ILL+
Sbjct: 238 LILENILLN 246
>XP_005268211
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLEKILL 8
           +VLE+ILL
Sbjct: 141 MVLERILL 148
>XP_005268018
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LVLEKILLS 9
           LVL+++LLS
Sbjct: 342 LVLQELLLS 350
>XP_005265051
          Length = 1034

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVLEKILLS 9
           L+LE ILL+
Sbjct: 238 LILENILLN 246
>NP_001092872
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLEKILL 8
           +VLE+ILL
Sbjct: 141 MVLERILL 148
>NP_060783
          Length = 1582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 750 LVLHKVLL 757
>NP_001010904
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LVLEKILLS 9
          L+LEK+L S
Sbjct: 11 LILEKMLKS 19
>NP_001129975
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LVLEKILLS 9
          LVLE +LLS
Sbjct: 8  LVLEFLLLS 16
>NP_001243064
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LVLEKILL 8
           +VLEKI++
Sbjct: 764 MVLEKIII 771
>NP_940969
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           +++KILLS
Sbjct: 94  IIQKILLS 101
>NP_004515
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVLEKILLS 9
           LV+E+ LLS
Sbjct: 974 LVMERALLS 982
>NP_001026973
          Length = 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVLEKILLS 9
           LV+E+ LLS
Sbjct: 974 LVMERALLS 982
>NP_001307
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LVLEKILL 8
           +VLEKI++
Sbjct: 820 MVLEKIII 827
>XP_006721961
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVLEKILLS 9
           LV+E+ LLS
Sbjct: 974 LVMERALLS 982
>XP_006721960
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVLEKILLS 9
           LV+E+ LLS
Sbjct: 974 LVMERALLS 982
>XP_005265966
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLEKILLS 9
           +++KILLS
Sbjct: 528 IIQKILLS 535
>XP_006713297
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 768 LVLHKVLL 775
>XP_006713296
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
>XP_006713295
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 736 LVLHKVLL 743
>XP_005265345
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 768 LVLHKVLL 775
>XP_006713294
          Length = 1652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 768 LVLHKVLL 775
>XP_006713293
          Length = 1667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
>XP_006713292
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
>XP_006713291
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 768 LVLHKVLL 775
>XP_006713290
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 751 LVLHKVLL 758
>XP_006713289
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
>XP_005265340
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 765 LVLHKVLL 772
>XP_005265339
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 765 LVLHKVLL 772
>XP_006713288
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 765 LVLHKVLL 772
>XP_005265337
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 765 LVLHKVLL 772
>XP_005265336
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 765 LVLHKVLL 772
>XP_006713287
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 765 LVLHKVLL 772
>XP_006713286
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 768 LVLHKVLL 775
>XP_005265332
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
>XP_006713285
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
>XP_006713284
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
>XP_006713283
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVLEKILL 8
           LVL K+LL
Sbjct: 783 LVLHKVLL 790
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.151    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 439,944
Number of extensions: 738
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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