Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245202                                                           18    1935
NP_001245200                                                           18    1935
NP_001161091                                                           18    1935
NP_000240                                                              18    1935
NP_001161090                                                           18    1935
NP_001161089                                                           18    1935
NP_001245203                                                           18    1935
XP_005265221                                                           18    1935
XP_005265220                                                           18    1935
NP_001243000                                                           16    7355
NP_001008781                                                           16    7355
XP_005257603                                                           16    7355
XP_006722058                                                           16    7355
XP_005257602                                                           16    7355
XP_006718827                                                           16    7355
NP_001243888                                                           15    9605
NP_001277                                                              15    9605
NP_001107604                                                           15    9605
NP_006257                                                              15    9605
NP_001035827                                                           15    9605
NP_001258705                                                           15    9605
NP_001258704                                                           15    9605
NP_001258703                                                           15    9605
XP_006712765                                                           15    9605
XP_006712764                                                           15    9605
XP_005246844                                                           15    9605
XP_006712763                                                           15    9605
XP_006712762                                                           15    9605
XP_006712761                                                           15    9605
>NP_001245202
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          LVES SLRK
Sbjct: 25 LVESTSLRK 33
>NP_001245200
          Length = 687

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVESISLRK 9
           LVES SLRK
Sbjct: 266 LVESTSLRK 274
>NP_001161091
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          LVES SLRK
Sbjct: 25 LVESTSLRK 33
>NP_000240
          Length = 756

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVESISLRK 9
           LVES SLRK
Sbjct: 266 LVESTSLRK 274
>NP_001161090
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          LVES SLRK
Sbjct: 25 LVESTSLRK 33
>NP_001161089
          Length = 658

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVESISLRK 9
           LVES SLRK
Sbjct: 168 LVESTSLRK 176
>NP_001245203
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          LVES SLRK
Sbjct: 25 LVESTSLRK 33
>XP_005265221
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          LVES SLRK
Sbjct: 25 LVESTSLRK 33
>XP_005265220
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          LVES SLRK
Sbjct: 25 LVESTSLRK 33
>NP_001243000
          Length = 5207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LVESISL 7
            LVESISL
Sbjct: 2601 LVESISL 2607
>NP_001008781
          Length = 4557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    VESISLRK 9
            ++SIS+RK
Sbjct: 1501 IDSISMRK 1508
>XP_005257603
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LVESISL 7
            LVESISL
Sbjct: 2650 LVESISL 2656
>XP_006722058
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LVESISL 7
            LVESISL
Sbjct: 2650 LVESISL 2656
>XP_005257602
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LVESISL 7
            LVESISL
Sbjct: 2650 LVESISL 2656
>XP_006718827
          Length = 3479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VESISLRK 9
           ++SIS+RK
Sbjct: 391 IDSISMRK 398
>NP_001243888
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESISLRK 9
           +SISLRK
Sbjct: 196 QSISLRK 202
>NP_001277
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESISLRK 9
           +SISLRK
Sbjct: 218 QSISLRK 224
>NP_001107604
          Length = 2694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LVESISLRK 9
           L+E +SL K
Sbjct: 983 LIEQVSLEK 991
>NP_006257
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          ++ SISLRK
Sbjct: 75 VIYSISLRK 83
>NP_001035827
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          ++ SISLRK
Sbjct: 20 VIYSISLRK 28
>NP_001258705
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          ++ SISLRK
Sbjct: 75 VIYSISLRK 83
>NP_001258704
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          ++ SISLRK
Sbjct: 74 VIYSISLRK 82
>NP_001258703
          Length = 885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LVESISLRK 9
          ++ SISLRK
Sbjct: 58 VIYSISLRK 66
>XP_006712765
          Length = 2679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LVESISLRK 9
           L+E +SL K
Sbjct: 955 LIEQVSLEK 963
>XP_006712764
          Length = 2697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LVESISLRK 9
            L+E +SL K
Sbjct: 1012 LIEQVSLEK 1020
>XP_005246844
          Length = 2707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LVESISLRK 9
           L+E +SL K
Sbjct: 983 LIEQVSLEK 991
>XP_006712763
          Length = 2716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LVESISLRK 9
            L+E +SL K
Sbjct: 1012 LIEQVSLEK 1020
>XP_006712762
          Length = 2723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LVESISLRK 9
            L+E +SL K
Sbjct: 1012 LIEQVSLEK 1020
>XP_006712761
          Length = 2736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LVESISLRK 9
            L+E +SL K
Sbjct: 1012 LIEQVSLEK 1020
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.133    0.295 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 287,366
Number of extensions: 247
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package