Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055726                                                              19     869
NP_001608                                                              18    1935
NP_001171983                                                           18    1935
NP_057608                                                              17    3301
XP_006721116                                                           17    3301
XP_005255419                                                           17    3301
XP_005255418                                                           17    3301
NP_612385                                                              17    4312
XP_005264808                                                           17    4312
XP_005264807                                                           17    4312
XP_005264806                                                           17    4312
XP_005264805                                                           17    4312
XP_005264804                                                           17    4312
NP_000857                                                              17    4312
NP_001123918                                                           16    5631
NP_071351                                                              16    7355
NP_002077                                                              16    7355
NP_001273586                                                           16    7355
NP_071437                                                              16    7355
NP_001128620                                                           16    7355
NP_001128619                                                           16    7355
NP_001128618                                                           16    7355
NP_005890                                                              16    7355
NP_114068                                                              16    7355
NP_114064                                                              16    7355
XP_006721966                                                           16    7355
XP_006716482                                                           16    7355
XP_005251207                                                           16    7355
XP_005263234                                                           16    7355
NP_005532                                                              15    9605
NP_001017915                                                           15    9605
NP_055462                                                              15    9605
NP_001171928                                                           15    9605
NP_055524                                                              15    9605
NP_116161                                                              15    9605
NP_001171927                                                           15    9605
NP_071926                                                              15    9605
NP_060362                                                              15    9605
NP_112598                                                              15    9605
XP_006725284                                                           15    9605
XP_006725283                                                           15    9605
XP_006725282                                                           15    9605
XP_006725281                                                           15    9605
XP_006725280                                                           15    9605
XP_006725279                                                           15    9605
XP_006725278                                                           15    9605
XP_005255766                                                           15    9605
XP_006721049                                                           15    9605
XP_005255765                                                           15    9605
XP_005255764                                                           15    9605
XP_005255763                                                           15    9605
XP_005255762                                                           15    9605
XP_005255761                                                           15    9605
XP_006714856                                                           15    9605
XP_005268556                                                           15    9605
XP_006714855                                                           15    9605
XP_006714854                                                           15    9605
XP_005268555                                                           15    9605
XP_005268554                                                           15    9605
XP_005246736                                                           15    9605
XP_005246735                                                           15    9605
XP_005246734                                                           15    9605
XP_005246733                                                           15    9605
NP_079345                                                              15    9605
>NP_055726
          Length = 961

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LTAEELLSK 9
           LTAEELL+K
Sbjct: 706 LTAEELLNK 714
>NP_001608
          Length = 726

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TAEELLSK 9
           TAEE+LSK
Sbjct: 657 TAEEILSK 664
>NP_001171983
          Length = 726

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TAEELLSK 9
           TAEE+LSK
Sbjct: 657 TAEEILSK 664
>NP_057608
          Length = 474

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LTAEELLSK 9
           LT EE+LSK
Sbjct: 174 LTDEEILSK 182
>XP_006721116
          Length = 413

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LTAEELLSK 9
           LT EE+LSK
Sbjct: 113 LTDEEILSK 121
>XP_005255419
          Length = 413

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LTAEELLSK 9
           LT EE+LSK
Sbjct: 113 LTDEEILSK 121
>XP_005255418
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LTAEELLSK 9
           LT EE+LSK
Sbjct: 174 LTDEEILSK 182
>NP_612385
          Length = 440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  AEELLSK 9
          AEELLSK
Sbjct: 88 AEELLSK 94
>XP_005264808
          Length = 366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LTAEELLSK 9
          LT+EELL++
Sbjct: 11 LTSEELLNR 19
>XP_005264807
          Length = 366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LTAEELLSK 9
          LT+EELL++
Sbjct: 11 LTSEELLNR 19
>XP_005264806
          Length = 366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LTAEELLSK 9
          LT+EELL++
Sbjct: 11 LTSEELLNR 19
>XP_005264805
          Length = 366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LTAEELLSK 9
          LT+EELL++
Sbjct: 11 LTSEELLNR 19
>XP_005264804
          Length = 366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LTAEELLSK 9
          LT+EELL++
Sbjct: 11 LTSEELLNR 19
>NP_000857
          Length = 366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LTAEELLSK 9
          LT+EELL++
Sbjct: 11 LTSEELLNR 19
>NP_001123918
          Length = 176

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LTAEELLSK 9
          +TAEE++ K
Sbjct: 12 ITAEEIIDK 20
>NP_071351
          Length = 2752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LTAEELLSK 9
            LTA ELL K
Sbjct: 1878 LTASELLLK 1886
>NP_002077
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  AEELLSK 9
          AEE+LSK
Sbjct: 70 AEEMLSK 76
>NP_001273586
          Length = 324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTAEELLSK 9
           +TAEEL  K
Sbjct: 288 ITAEELAEK 296
>NP_071437
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LTAEELLS 8
          LTAEE+ S
Sbjct: 75 LTAEEIFS 82
>NP_001128620
          Length = 393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LTAEELLS 8
          LTAEE+ S
Sbjct: 8  LTAEEIFS 15
>NP_001128619
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LTAEELLS 8
          LTAEE+ S
Sbjct: 75 LTAEEIFS 82
>NP_001128618
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LTAEELLS 8
          LTAEE+ S
Sbjct: 75 LTAEEIFS 82
>NP_005890
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LTAEELLS 8
           LTA++LLS
Sbjct: 555 LTAQDLLS 562
>NP_114068
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LTAEELLS 8
           LTA++LLS
Sbjct: 555 LTAQDLLS 562
>NP_114064
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LTAEELLS 8
           LTA++LLS
Sbjct: 555 LTAQDLLS 562
>XP_006721966
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LTAEELLS 8
           LTA++LLS
Sbjct: 485 LTAQDLLS 492
>XP_006716482
          Length = 324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTAEELLSK 9
           +TAEEL  K
Sbjct: 288 ITAEELAEK 296
>XP_005251207
          Length = 324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTAEELLSK 9
           +TAEEL  K
Sbjct: 288 ITAEELAEK 296
>XP_005263234
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LTAEELLS 8
          LTAEE+ S
Sbjct: 75 LTAEEIFS 82
>NP_005532
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  AEELLSK 9
          AEELLS+
Sbjct: 15 AEELLSR 21
>NP_001017915
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  AEELLSK 9
          AEELLS+
Sbjct: 15 AEELLSR 21
>NP_055462
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1706 TSESLLSK 1713
>NP_001171928
          Length = 1739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1703 TSESLLSK 1710
>NP_055524
          Length = 3546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T +ELLSK
Sbjct: 3315 TLQELLSK 3322
>NP_116161
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TAEELLS 8
           T+EELLS
Sbjct: 531 TSEELLS 537
>NP_001171927
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1706 TSESLLSK 1713
>NP_071926
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LTAEELLSK 9
            LTAEEL ++
Sbjct: 1142 LTAEELTNQ 1150
>NP_060362
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AEELLSK 9
           AE+LLSK
Sbjct: 151 AEQLLSK 157
>NP_112598
          Length = 5088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LTAEELLS 8
            +TA ELLS
Sbjct: 2181 ITASELLS 2188
>XP_006725284
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1528 TSESLLSK 1535
>XP_006725283
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1564 TSESLLSK 1571
>XP_006725282
          Length = 1613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1577 TSESLLSK 1584
>XP_006725281
          Length = 1733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1697 TSESLLSK 1704
>XP_006725280
          Length = 1741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1705 TSESLLSK 1712
>XP_006725279
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1707 TSESLLSK 1714
>XP_006725278
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1707 TSESLLSK 1714
>XP_005255766
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1528 TSESLLSK 1535
>XP_006721049
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1564 TSESLLSK 1571
>XP_005255765
          Length = 1613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1577 TSESLLSK 1584
>XP_005255764
          Length = 1733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1697 TSESLLSK 1704
>XP_005255763
          Length = 1741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1705 TSESLLSK 1712
>XP_005255762
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1707 TSESLLSK 1714
>XP_005255761
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TAEELLSK 9
            T+E LLSK
Sbjct: 1707 TSESLLSK 1714
>XP_006714856
          Length = 1346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LTAEELLSK 9
           LTAEEL ++
Sbjct: 944 LTAEELTNQ 952
>XP_005268556
          Length = 1466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LTAEELLSK 9
            LTAEEL ++
Sbjct: 1064 LTAEELTNQ 1072
>XP_006714855
          Length = 1473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LTAEELLSK 9
            LTAEEL ++
Sbjct: 1071 LTAEELTNQ 1079
>XP_006714854
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LTAEELLSK 9
            LTAEEL ++
Sbjct: 1084 LTAEELTNQ 1092
>XP_005268555
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LTAEELLSK 9
            LTAEEL ++
Sbjct: 1122 LTAEELTNQ 1130
>XP_005268554
          Length = 1531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LTAEELLSK 9
            LTAEEL ++
Sbjct: 1142 LTAEELTNQ 1150
>XP_005246736
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AEELLSK 9
           AE+LLSK
Sbjct: 193 AEQLLSK 199
>XP_005246735
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AEELLSK 9
           AE+LLSK
Sbjct: 193 AEQLLSK 199
>XP_005246734
          Length = 934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AEELLSK 9
           AE+LLSK
Sbjct: 151 AEQLLSK 157
>XP_005246733
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AEELLSK 9
           AE+LLSK
Sbjct: 193 AEQLLSK 199
>NP_079345
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TAEELLS 8
           T+EELLS
Sbjct: 473 TSEELLS 479
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.118    0.259 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 470,489
Number of extensions: 602
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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