Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1935
XP_006716142                                                           18    1935
XP_005250088                                                           18    1935
XP_006716141                                                           18    1935
XP_005250085                                                           18    1935
XP_006716140                                                           18    1935
XP_005250084                                                           18    1935
XP_005250083                                                           18    1935
XP_005250082                                                           18    1935
NP_001005855                                                           17    3301
NP_001231892                                                           16    5631
NP_001104488                                                           16    5631
NP_660093                                                              16    5631
NP_892009                                                              16    5631
XP_006718429                                                           16    5631
XP_006718428                                                           16    5631
XP_006718427                                                           16    5631
NP_057567                                                              16    7355
NP_001265150                                                           16    7355
XP_005265284                                                           16    7355
XP_005265283                                                           16    7355
XP_005265282                                                           16    7355
NP_005069                                                              15    9605
NP_065959                                                              15    9605
NP_001269910                                                           15    9605
NP_001269909                                                           15    9605
NP_001098662                                                           15    9605
NP_001269908                                                           15    9605
NP_001269911                                                           15    9605
NP_001135906                                                           15    9605
NP_001123525                                                           15    9605
NP_036347                                                              15    9605
NP_115754                                                              15    9605
XP_006725136                                                           15    9605
XP_006725135                                                           15    9605
XP_006725134                                                           15    9605
XP_006725133                                                           15    9605
XP_006725132                                                           15    9605
XP_006725131                                                           15    9605
XP_006725130                                                           15    9605
XP_006725129                                                           15    9605
XP_006725127                                                           15    9605
XP_005254690                                                           15    9605
XP_006720728                                                           15    9605
XP_006720727                                                           15    9605
XP_005254679                                                           15    9605
XP_005254685                                                           15    9605
XP_006720726                                                           15    9605
XP_005254682                                                           15    9605
XP_006720725                                                           15    9605
XP_005254680                                                           15    9605
XP_005250881                                                           15    9605
XP_005250880                                                           15    9605
XP_006716587                                                           15    9605
XP_006716586                                                           15    9605
XP_006716585                                                           15    9605
XP_006716584                                                           15    9605
XP_005250878                                                           15    9605
XP_006716583                                                           15    9605
XP_005250877                                                           15    9605
>NP_733751
          Length = 4911

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2918 LSSLLANEK 2926
>XP_006716142
          Length = 4927

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2935 LSSLLANEK 2943
>XP_005250088
          Length = 4928

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2935 LSSLLANEK 2943
>XP_006716141
          Length = 4959

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2935 LSSLLANEK 2943
>XP_005250085
          Length = 4979

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2935 LSSLLANEK 2943
>XP_006716140
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2935 LSSLLANEK 2943
>XP_005250084
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2935 LSSLLANEK 2943
>XP_005250083
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2934 LSSLLANEK 2942
>XP_005250082
          Length = 4983

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSLRANEK 9
            LSSL ANEK
Sbjct: 2935 LSSLLANEK 2943
>NP_001005855
          Length = 387

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSLRANEK 9
           + SLR+NEK
Sbjct: 370 MKSLRSNEK 378
>NP_001231892
          Length = 2488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSL+ NEK
Sbjct: 503 SSLKGNEK 510
>NP_001104488
          Length = 2365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSL+ NEK
Sbjct: 416 SSLKGNEK 423
>NP_660093
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSL+ NEK
Sbjct: 480 SSLKGNEK 487
>NP_892009
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSL+ NEK
Sbjct: 480 SSLKGNEK 487
>XP_006718429
          Length = 2416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSL+ NEK
Sbjct: 431 SSLKGNEK 438
>XP_006718428
          Length = 2455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSL+ NEK
Sbjct: 503 SSLKGNEK 510
>XP_006718427
          Length = 2465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSL+ NEK
Sbjct: 480 SSLKGNEK 487
>NP_057567
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSLR+N K
Sbjct: 286 SSLRSNSK 293
>NP_001265150
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSLR+N K
Sbjct: 247 SSLRSNSK 254
>XP_005265284
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSLR+N K
Sbjct: 247 SSLRSNSK 254
>XP_005265283
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSLR+N K
Sbjct: 286 SSLRSNSK 293
>XP_005265282
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSLRANEK 9
           SSLR+N K
Sbjct: 286 SSLRSNSK 293
>NP_005069
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_065959
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001269910
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 200 SLRASEK 206
>NP_001269909
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001098662
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001269908
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 207 SLRASEK 213
>NP_001269911
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 151 SLRASEK 157
>NP_001135906
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LSSLRAN 7
           LSSL+AN
Sbjct: 812 LSSLKAN 818
>NP_001123525
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>NP_036347
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LSSLRAN 7
           LSSL+AN
Sbjct: 865 LSSLKAN 871
>NP_115754
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006725136
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006725135
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006725134
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006725133
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006725132
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006725131
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006725130
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 359 VSSLRPNRK 367
>XP_006725129
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 399 VSSLRPNRK 407
>XP_006725127
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 399 VSSLRPNRK 407
>XP_005254690
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 207 SLRASEK 213
>XP_006720728
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 206 SLRASEK 212
>XP_006720727
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 212 SLRASEK 218
>XP_005254679
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 217 SLRASEK 223
>XP_005254685
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 217 SLRASEK 223
>XP_006720726
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 206 SLRASEK 212
>XP_005254682
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 217 SLRASEK 223
>XP_006720725
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 212 SLRASEK 218
>XP_005254680
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLRANEK 9
           SLRA+EK
Sbjct: 217 SLRASEK 223
>XP_005250881
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_005250880
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006716587
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006716586
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006716585
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_006716584
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 358 VSSLRPNRK 366
>XP_005250878
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 359 VSSLRPNRK 367
>XP_006716583
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 399 VSSLRPNRK 407
>XP_005250877
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSLRANEK 9
           +SSLR N K
Sbjct: 399 VSSLRPNRK 407
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.112    0.253 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 328,479
Number of extensions: 377
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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