Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_001185763                                                           18    1135
NP_055459                                                              18    1135
XP_006726436                                                           18    1135
XP_006726410                                                           18    1135
XP_006711784                                                           18    1135
XP_006711719                                                           18    1135
XP_006711718                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711712                                                           18    1135
XP_006711711                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
XP_005277503                                                           18    1135
XP_005273038                                                           18    1135
XP_006711708                                                           18    1135
XP_005277500                                                           18    1135
XP_006711707                                                           18    1135
XP_005277499                                                           18    1135
XP_006711706                                                           18    1135
XP_006711705                                                           18    1135
XP_006711164                                                           18    1135
XP_005276114                                                           18    1135
XP_006710122                                                           18    1135
XP_005265253                                                           17    3301
NP_886552                                                              17    3301
NP_878918                                                              15    9605
NP_055995                                                              15    9605
NP_001248348                                                           15    9605
NP_004624                                                              15    9605
NP_002575                                                              15    9605
NP_001128726                                                           15    9605
NP_039236                                                              15    9605
NP_065878                                                              15    9605
NP_001245275                                                           15    9605
XP_005259257                                                           15    9605
XP_005267517                                                           15    9605
XP_005267516                                                           15    9605
XP_005267515                                                           15    9605
XP_005267514                                                           15    9605
XP_005267513                                                           15    9605
XP_005267512                                                           15    9605
XP_005267511                                                           15    9605
XP_005263212                                                           15    9605
XP_005263211                                                           15    9605
XP_006712799                                                           15    9605
XP_006712798                                                           15    9605
XP_006712797                                                           15    9605
XP_005245941                                                           15    9605
NP_003361                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2176 LRTKVSKQE 2184
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2282 LRTKVSKQE 2290
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2282 LRTKVSKQE 2290
>XP_006726436
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LRIKVSKQE 9
          LR KVSKQE
Sbjct: 60 LRTKVSKQE 68
>XP_006726410
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2023 LRTKVSKQE 2031
>XP_006711784
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LRIKVSKQE 9
          LR KVSKQE
Sbjct: 60 LRTKVSKQE 68
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2238 LRTKVSKQE 2246
>XP_006711718
          Length = 1436

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 1289 LRTKVSKQE 1297
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2238 LRTKVSKQE 2246
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2347 LRTKVSKQE 2355
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2281 LRTKVSKQE 2289
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2282 LRTKVSKQE 2290
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2285 LRTKVSKQE 2293
>XP_006711712
          Length = 2473

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2326 LRTKVSKQE 2334
>XP_006711711
          Length = 2482

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2335 LRTKVSKQE 2343
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2347 LRTKVSKQE 2355
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2348 LRTKVSKQE 2356
>XP_005277503
          Length = 2498

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2445 LRTKVSKQE 2453
>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2445 LRTKVSKQE 2453
>XP_006711708
          Length = 2512

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2365 LRTKVSKQE 2373
>XP_005277500
          Length = 2525

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2445 LRTKVSKQE 2453
>XP_006711707
          Length = 2553

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2406 LRTKVSKQE 2414
>XP_005277499
          Length = 2561

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2445 LRTKVSKQE 2453
>XP_006711706
          Length = 2591

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2444 LRTKVSKQE 2452
>XP_006711705
          Length = 2592

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2445 LRTKVSKQE 2453
>XP_006711164
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIKVSKQE 9
            LR KVSKQE
Sbjct: 2023 LRTKVSKQE 2031
>XP_005276114
          Length = 134

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LRIKVSKQE 9
          LR KVSKQE
Sbjct: 30 LRTKVSKQE 38
>XP_006710122
          Length = 126

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LRIKVSKQE 9
          LR KVSKQE
Sbjct: 60 LRTKVSKQE 68
>XP_005265253
          Length = 434

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LRIKVSKQE 9
           LR+K++K+E
Sbjct: 311 LRLKIAKEE 319
>NP_886552
          Length = 434

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LRIKVSKQE 9
           LR+K++K+E
Sbjct: 311 LRLKIAKEE 319
>NP_878918
          Length = 6907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>NP_055995
          Length = 6885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>NP_001248348
          Length = 296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 226 LRIKKKKEE 234
>NP_004624
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 226 LRIKKKKEE 234
>NP_002575
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 160 LRIKFGKKE 168
>NP_001128726
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 160 LRIKFGKKE 168
>NP_039236
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 158 LRIKFGKKE 166
>NP_065878
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RIKVSKQE 9
           ++K+ KQE
Sbjct: 278 KVKIKKQE 285
>NP_001245275
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIKVSKQE 9
           ++IK+SK E
Sbjct: 191 IKIKISKGE 199
>XP_005259257
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KVSKQE 9
           KVSKQE
Sbjct: 237 KVSKQE 242
>XP_005267517
          Length = 6883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5864 LRVAIRKQE 5872
>XP_005267516
          Length = 6884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>XP_005267515
          Length = 6899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>XP_005267514
          Length = 6908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>XP_005267513
          Length = 6921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>XP_005267512
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>XP_005267511
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRIKVSKQE 9
            LR+ + KQE
Sbjct: 5903 LRVAIRKQE 5911
>XP_005263212
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RIKVSKQE 9
           ++K+ KQE
Sbjct: 278 KVKIKKQE 285
>XP_005263211
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RIKVSKQE 9
           ++K+ KQE
Sbjct: 278 KVKIKKQE 285
>XP_006712799
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 251 LRIKKKKEE 259
>XP_006712798
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 141 LRIKKKKEE 149
>XP_006712797
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 226 LRIKKKKEE 234
>XP_005245941
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIKVSKQE 9
           LRIK  K+E
Sbjct: 158 LRIKFGKKE 166
>NP_003361
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KVSKQE 9
           KVSKQE
Sbjct: 237 KVSKQE 242
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.128    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 367,488
Number of extensions: 767
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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