Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     665
NP_005504                                                              18    1935
NP_001360                                                              17    4312
NP_001265237                                                           17    4312
NP_001265235                                                           17    4312
NP_001265236                                                           17    4312
NP_001265234                                                           17    4312
XP_005248319                                                           17    4312
NP_542409                                                              17    4312
NP_775820                                                              16    5631
NP_004723                                                              16    5631
XP_005256906                                                           16    5631
NP_001182583                                                           16    7355
NP_115916                                                              16    7355
NP_001182582                                                           16    7355
NP_001076582                                                           16    7355
NP_852150                                                              16    7355
NP_852129                                                              16    7355
NP_852127                                                              16    7355
NP_852128                                                              16    7355
NP_852120                                                              16    7355
NP_852130                                                              16    7355
NP_002702                                                              16    7355
NP_852119                                                              16    7355
NP_852106                                                              16    7355
XP_005250530                                                           16    7355
XP_006711811                                                           16    7355
XP_005273119                                                           16    7355
XP_005273120                                                           16    7355
XP_005273118                                                           16    7355
XP_005273117                                                           16    7355
XP_005273116                                                           16    7355
XP_006711810                                                           16    7355
XP_006711809                                                           16    7355
XP_006711808                                                           16    7355
XP_006711807                                                           16    7355
XP_006711806                                                           16    7355
XP_006711805                                                           16    7355
XP_006711804                                                           16    7355
XP_006711803                                                           16    7355
XP_006711802                                                           16    7355
XP_006711801                                                           16    7355
XP_006711800                                                           16    7355
NP_852121                                                              16    7355
NP_079317                                                              16    7355
NP_055087                                                              15    9605
NP_775734                                                              15    9605
NP_001124198                                                           15    9605
XP_005254194                                                           15    9605
XP_006714048                                                           15    9605
XP_005248267                                                           15    9605
>NP_443179
          Length = 2170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           LREST EGT
Sbjct: 553 LRESTTEGT 561
>NP_005504
          Length = 439

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRESTIEG 8
           LREST++G
Sbjct: 281 LRESTVQG 288
>NP_001360
          Length = 4624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRESTIEG 8
           L++STIEG
Sbjct: 496 LQDSTIEG 503
>NP_001265237
          Length = 164

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           LRE +I+GT
Sbjct: 120 LREHSIDGT 128
>NP_001265235
          Length = 161

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           LRE +I+GT
Sbjct: 96  LREHSIDGT 104
>NP_001265236
          Length = 153

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LRE +I+GT
Sbjct: 88 LREHSIDGT 96
>NP_001265234
          Length = 185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           LRE +I+GT
Sbjct: 120 LREHSIDGT 128
>XP_005248319
          Length = 4609

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRESTIEG 8
           L++STIEG
Sbjct: 481 LQDSTIEG 488
>NP_542409
          Length = 185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           LRE +I+GT
Sbjct: 120 LREHSIDGT 128
>NP_775820
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  RESTIEG 8
          REST++G
Sbjct: 46 RESTVDG 52
>NP_004723
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LRESTIEGT 9
          LREST  GT
Sbjct: 68 LRESTGRGT 76
>XP_005256906
          Length = 375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LRESTIEGT 9
          LREST  GT
Sbjct: 68 LRESTGRGT 76
>NP_001182583
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRESTIEG 8
           LRE+ +EG
Sbjct: 255 LREAVVEG 262
>NP_115916
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRESTIEG 8
           LRE+ +EG
Sbjct: 255 LREAVVEG 262
>NP_001182582
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRESTIEG 8
           LRE+ +EG
Sbjct: 255 LREAVVEG 262
>NP_001076582
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRESTIEG 8
           LRE+ +EG
Sbjct: 255 LREAVVEG 262
>NP_852150
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRESTIEG 8
           LRE+ +EG
Sbjct: 255 LREAVVEG 262
>NP_852129
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>NP_852127
          Length = 164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 47 LRQSTVKAT 55
>NP_852128
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>NP_852120
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>NP_852130
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>NP_002702
          Length = 1122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           L+EST EG+
Sbjct: 497 LKESTEEGS 505
>NP_852119
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>NP_852106
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>XP_005250530
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           L+EST EG+
Sbjct: 296 LKESTEEGS 304
>XP_006711811
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>XP_005273119
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>XP_005273120
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>XP_005273118
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>XP_005273117
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>XP_005273116
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>XP_006711810
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711809
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711808
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711807
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711806
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711805
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711804
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711803
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711802
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711801
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>XP_006711800
          Length = 170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 53 LRQSTVKAT 61
>NP_852121
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRESTIEGT 9
          LR+ST++ T
Sbjct: 11 LRQSTVKAT 19
>NP_079317
          Length = 165

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LRESTIEG 8
          L EST+EG
Sbjct: 63 LLESTLEG 70
>NP_055087
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           LR++ ++GT
Sbjct: 644 LRDAVVDGT 652
>NP_775734
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   RESTIEG 8
           RES IEG
Sbjct: 467 RESPIEG 473
>NP_001124198
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   RESTIEG 8
           RES IEG
Sbjct: 467 RESPIEG 473
>XP_005254194
          Length = 1689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LRESTIEGT 9
           LR++ ++GT
Sbjct: 644 LRDAVVDGT 652
>XP_006714048
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   RESTIEG 8
           RES IEG
Sbjct: 478 RESPIEG 484
>XP_005248267
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   RESTIEG 8
           RES IEG
Sbjct: 478 RESPIEG 484
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.124    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 520,270
Number of extensions: 873
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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