Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055726                                                              19     665
NP_055572                                                              18    1482
NP_001128715                                                           17    2528
NP_001128717                                                           17    2528
NP_001128716                                                           17    2528
NP_000347                                                              17    2528
NP_001182070                                                           17    2528
XP_005268564                                                           17    2528
XP_005268563                                                           17    2528
XP_005268562                                                           17    2528
XP_005268561                                                           17    2528
XP_005268560                                                           17    2528
XP_005268559                                                           17    2528
NP_001120936                                                           17    3301
NP_001137236                                                           17    3301
NP_001137235                                                           17    3301
NP_570140                                                              17    3301
NP_061761                                                              17    3301
NP_061757                                                              17    3301
NP_061758                                                              17    3301
NP_056484                                                              17    3301
NP_061762                                                              17    3301
NP_061755                                                              17    3301
NP_061754                                                              17    3301
NP_054878                                                              17    4312
NP_001073626                                                           17    4312
NP_115885                                                              17    4312
XP_006719623                                                           17    4312
XP_005269136                                                           17    4312
XP_005269138                                                           17    4312
XP_006713183                                                           17    4312
XP_006713182                                                           17    4312
NP_997309                                                              17    4312
NP_056224                                                              16    5631
XP_006721217                                                           16    5631
XP_005255871                                                           16    5631
XP_005252949                                                           16    5631
XP_005252948                                                           16    5631
NP_631913                                                              16    5631
NP_001138872                                                           16    5631
NP_848632                                                              16    5631
NP_061992                                                              16    7355
NP_620411                                                              16    7355
NP_005867                                                              16    7355
NP_061759                                                              16    7355
NP_061760                                                              16    7355
XP_005271777                                                           16    7355
XP_006712257                                                           16    7355
XP_006712255                                                           16    7355
XP_006712252                                                           16    7355
XP_005246294                                                           16    7355
XP_006712251                                                           16    7355
XP_005246293                                                           16    7355
XP_006712250                                                           16    7355
NP_001035194                                                           16    7355
NP_061753                                                              16    7355
NP_003323                                                              15    9605
NP_937758                                                              15    9605
NP_001277162                                                           15    9605
NP_001254772                                                           15    9605
NP_004889                                                              15    9605
NP_078966                                                              15    9605
NP_001123482                                                           15    9605
NP_001271247                                                           15    9605
NP_001271246                                                           15    9605
NP_001138749                                                           15    9605
NP_077300                                                              15    9605
NP_001128573                                                           15    9605
XP_005261794                                                           15    9605
XP_006723413                                                           15    9605
XP_006714117                                                           15    9605
XP_005265844                                                           15    9605
NP_116168                                                              15    9605
>NP_055726
          Length = 961

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LPAQAQAT 8
           LPAQAQAT
Sbjct: 453 LPAQAQAT 460
>NP_055572
          Length = 1016

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LPAQAQATS 9
           +P QAQATS
Sbjct: 584 VPVQAQATS 592
>NP_001128715
          Length = 1488

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 975 PAQAQAAS 982
>NP_001128717
          Length = 1412

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 898 PAQAQAAS 905
>NP_001128716
          Length = 1451

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 975 PAQAQAAS 982
>NP_000347
          Length = 1411

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 898 PAQAQAAS 905
>NP_001182070
          Length = 1450

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 975 PAQAQAAS 982
>XP_005268564
          Length = 1449

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 935 PAQAQAAS 942
>XP_005268563
          Length = 1488

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    PAQAQATS 9
            PAQAQA S
Sbjct: 1012 PAQAQAAS 1019
>XP_005268562
          Length = 1489

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 975 PAQAQAAS 982
>XP_005268561
          Length = 1525

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    PAQAQATS 9
            PAQAQA S
Sbjct: 1012 PAQAQAAS 1019
>XP_005268560
          Length = 1525

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    PAQAQATS 9
            PAQAQA S
Sbjct: 1011 PAQAQAAS 1018
>XP_005268559
          Length = 1526

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    PAQAQATS 9
            PAQAQA S
Sbjct: 1012 PAQAQAAS 1019
>NP_001120936
          Length = 3925

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LPAQAQATS 9
            LPA+AQA S
Sbjct: 3752 LPARAQAKS 3760
>NP_001137236
          Length = 351

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LPAQAQAT 8
           +PAQAQ+T
Sbjct: 289 VPAQAQST 296
>NP_001137235
          Length = 318

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LPAQAQAT 8
           +PAQAQ+T
Sbjct: 289 VPAQAQST 296
>NP_570140
          Length = 282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LPAQAQAT 8
           +PAQAQ+T
Sbjct: 253 VPAQAQST 260
>NP_061761
          Length = 795

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 677 PAQAQADS 684
>NP_061757
          Length = 798

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 678 PAQAQADS 685
>NP_061758
          Length = 787

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 678 PAQAQADS 685
>NP_056484
          Length = 795

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 677 PAQAQADS 684
>NP_061762
          Length = 794

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 676 PAQAQADS 683
>NP_061755
          Length = 795

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 678 PAQAQADS 685
>NP_061754
          Length = 797

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           PAQAQA S
Sbjct: 678 PAQAQADS 685
>NP_054878
          Length = 2564

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    PAQAQAT 8
            PAQ+QAT
Sbjct: 2288 PAQSQAT 2294
>NP_001073626
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LPAQAQATS 9
           LP++AQA+S
Sbjct: 121 LPSRAQASS 129
>NP_115885
          Length = 731

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LPAQAQATS 9
           LP++AQA+S
Sbjct: 121 LPSRAQASS 129
>XP_006719623
          Length = 750

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LPAQAQATS 9
           LP++AQA+S
Sbjct: 121 LPSRAQASS 129
>XP_005269136
          Length = 784

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LPAQAQATS 9
           LP++AQA+S
Sbjct: 155 LPSRAQASS 163
>XP_005269138
          Length = 798

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LPAQAQATS 9
           LP++AQA+S
Sbjct: 169 LPSRAQASS 177
>XP_006713183
          Length = 2258

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    PAQAQAT 8
            PAQ+QAT
Sbjct: 1982 PAQSQAT 1988
>XP_006713182
          Length = 2422

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    PAQAQAT 8
            PAQ+QAT
Sbjct: 2288 PAQSQAT 2294
>NP_997309
          Length = 318

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PAQAQATS 9
          P QAQAT+
Sbjct: 15 PGQAQATA 22
>NP_056224
          Length = 3123

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LPAQAQA 7
            LP+QAQA
Sbjct: 1554 LPSQAQA 1560
>XP_006721217
          Length = 581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LPAQAQA 7
          LPAQAQ+
Sbjct: 35 LPAQAQS 41
>XP_005255871
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LPAQAQA 7
          LPAQAQ+
Sbjct: 35 LPAQAQS 41
>XP_005252949
          Length = 1001

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+AQAT
Sbjct: 590 PARAQAT 596
>XP_005252948
          Length = 1007

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+AQAT
Sbjct: 558 PARAQAT 564
>NP_631913
          Length = 665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LPAQAQA 7
          LPAQAQ+
Sbjct: 35 LPAQAQS 41
>NP_001138872
          Length = 583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LPAQAQA 7
          LPAQAQ+
Sbjct: 35 LPAQAQS 41
>NP_848632
          Length = 1039

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+AQAT
Sbjct: 590 PARAQAT 596
>NP_061992
          Length = 797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   PAQAQA 7
           PAQAQA
Sbjct: 678 PAQAQA 683
>NP_620411
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LPAQAQATS 9
           +PAQ+QA S
Sbjct: 380 VPAQSQAGS 388
>NP_005867
          Length = 3267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 212 PRQAQAT 218
>NP_061759
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   PAQAQA 7
           PAQAQA
Sbjct: 680 PAQAQA 685
>NP_061760
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   PAQAQA 7
           PAQAQA
Sbjct: 678 PAQAQA 683
>XP_005271777
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LPAQAQATS 9
           +PAQ+QA S
Sbjct: 201 VPAQSQAGS 209
>XP_006712257
          Length = 1718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 212 PRQAQAT 218
>XP_006712255
          Length = 2622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 212 PRQAQAT 218
>XP_006712252
          Length = 3163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 108 PRQAQAT 114
>XP_005246294
          Length = 3173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 118 PRQAQAT 124
>XP_006712251
          Length = 3176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 121 PRQAQAT 127
>XP_005246293
          Length = 3206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 212 PRQAQAT 218
>XP_006712250
          Length = 3248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PAQAQAT 8
           P QAQAT
Sbjct: 193 PRQAQAT 199
>NP_001035194
          Length = 4493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LPAQAQATS 9
           LP  A+ATS
Sbjct: 374 LPTTAEATS 382
>NP_061753
          Length = 800

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   PAQAQA 7
           PAQAQA
Sbjct: 678 PAQAQA 683
>NP_003323
          Length = 113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  PAQAQATS 9
          P QAQA S
Sbjct: 24 PVQAQAQS 31
>NP_937758
          Length = 112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  PAQAQATS 9
          P QAQA S
Sbjct: 24 PVQAQAQS 31
>NP_001277162
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PAQAQAT 8
          P+Q+QAT
Sbjct: 33 PSQSQAT 39
>NP_001254772
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LPAQAQAT 8
           LP+Q Q+T
Sbjct: 649 LPSQTQST 656
>NP_004889
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LPAQAQAT 8
           LP+Q Q+T
Sbjct: 649 LPSQTQST 656
>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LPAQAQAT 8
            +PA AQ+T
Sbjct: 6121 MPASAQST 6128
>NP_001123482
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PAQAQAT 8
          P+Q+QAT
Sbjct: 33 PSQSQAT 39
>NP_001271247
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+A+AT
Sbjct: 301 PAEAEAT 307
>NP_001271246
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+A+AT
Sbjct: 305 PAEAEAT 311
>NP_001138749
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PAQAQATS 9
           P+QAQA S
Sbjct: 229 PSQAQAGS 236
>NP_077300
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+A+AT
Sbjct: 333 PAEAEAT 339
>NP_001128573
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+A+AT
Sbjct: 382 PAEAEAT 388
>XP_005261794
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PAQAQAT 8
           PA+A+AT
Sbjct: 383 PAEAEAT 389
>XP_006723413
          Length = 157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  PAQAQATS 9
          P QAQA S
Sbjct: 68 PVQAQAQS 75
>XP_006714117
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LPAQAQAT 8
           LP+Q Q+T
Sbjct: 649 LPSQTQST 656
>XP_005265844
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LPAQAQAT 8
           LP+Q Q+T
Sbjct: 649 LPSQTQST 656
>NP_116168
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LPAQAQA 7
           LP QAQA
Sbjct: 560 LPPQAQA 566
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.102    0.253 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 451,022
Number of extensions: 643
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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