Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              20     509
XP_005251512                                                           20     509
NP_057484                                                              16    5631
XP_006713136                                                           16    5631
NP_001171718                                                           16    7355
NP_062565                                                              16    7355
NP_001171715                                                           16    7355
NP_001171720                                                           16    7355
NP_001171714                                                           16    7355
NP_001171717                                                           16    7355
NP_001171722                                                           16    7355
NP_001171721                                                           16    7355
NP_001171723                                                           16    7355
NP_001171716                                                           16    7355
NP_001171719                                                           16    7355
XP_006717541                                                           16    7355
XP_005252593                                                           16    7355
XP_005252592                                                           16    7355
XP_005252591                                                           16    7355
XP_006717540                                                           16    7355
XP_006717539                                                           16    7355
XP_006717538                                                           16    7355
XP_006717537                                                           16    7355
XP_005252589                                                           16    7355
XP_006717536                                                           16    7355
XP_006717535                                                           16    7355
XP_006717534                                                           16    7355
XP_005252588                                                           16    7355
XP_005252587                                                           16    7355
XP_005252585                                                           16    7355
NP_002687                                                              16    7355
NP_000124                                                              15    9605
NP_115532                                                              15    9605
NP_076414                                                              15    9605
NP_001002259                                                           15    9605
NP_001193785                                                           15    9605
NP_001245245                                                           15    9605
NP_060568                                                              15    9605
NP_001245244                                                           15    9605
XP_005262454                                                           15    9605
XP_006719211                                                           15    9605
XP_006719210                                                           15    9605
XP_006719209                                                           15    9605
XP_006719208                                                           15    9605
XP_006719207                                                           15    9605
XP_006719206                                                           15    9605
XP_006719205                                                           15    9605
XP_006719204                                                           15    9605
XP_006719203                                                           15    9605
XP_006719202                                                           15    9605
XP_006719201                                                           15    9605
XP_006719200                                                           15    9605
XP_005247237                                                           15    9605
XP_006713587                                                           15    9605
XP_005247233                                                           15    9605
XP_006713586                                                           15    9605
>NP_004963
          Length = 1132

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LMMTEMEGT 9
          L MTEMEGT
Sbjct: 6  LTMTEMEGT 14
>XP_005251512
          Length = 1132

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LMMTEMEGT 9
          L MTEMEGT
Sbjct: 6  LTMTEMEGT 14
>NP_057484
          Length = 129

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LMMTEME 7
           L+MTEME
Sbjct: 97  LIMTEME 103
>XP_006713136
          Length = 1022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3 MTEMEGT 9
         MT+M+GT
Sbjct: 1 MTDMDGT 7
>NP_001171718
          Length = 1273

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_062565
          Length = 1356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171715
          Length = 1340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171720
          Length = 1244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 487 LRSTKMEGT 495
>NP_001171714
          Length = 1353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171717
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171722
          Length = 1000

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171721
          Length = 1031

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171723
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171716
          Length = 1319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_001171719
          Length = 1266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 487 LRSTKMEGT 495
>XP_006717541
          Length = 1295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 487 LRSTKMEGT 495
>XP_005252593
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_005252592
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_005252591
          Length = 1030

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_006717540
          Length = 1141

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_006717539
          Length = 1170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_006717538
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_006717537
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 487 LRSTKMEGT 495
>XP_005252589
          Length = 1309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 487 LRSTKMEGT 495
>XP_006717536
          Length = 1314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 492 LRSTKMEGT 500
>XP_006717535
          Length = 1316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_006717534
          Length = 1321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 499 LRSTKMEGT 507
>XP_005252588
          Length = 1323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_005252587
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>XP_005252585
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMMTEMEGT 9
           L  T+MEGT
Sbjct: 531 LRSTKMEGT 539
>NP_002687
          Length = 172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  MMTEMEGT 9
          + TE+EGT
Sbjct: 30 LFTEVEGT 37
>NP_000124
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MTEMEGT 9
           +TE+EGT
Sbjct: 416 VTEVEGT 422
>NP_115532
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>NP_076414
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>NP_001002259
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>NP_001193785
          Length = 905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>NP_001245245
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   MTEMEG 8
           MTEM+G
Sbjct: 261 MTEMQG 266
>NP_060568
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   MTEMEG 8
           MTEM+G
Sbjct: 261 MTEMQG 266
>NP_001245244
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   MTEMEG 8
           MTEM+G
Sbjct: 292 MTEMQG 297
>XP_005262454
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MTEMEGT 9
           +TE+EGT
Sbjct: 373 VTEVEGT 379
>XP_006719211
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 290 LMTQIQGT 297
>XP_006719210
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719209
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719208
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719207
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719206
          Length = 1046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 542 LMTQIQGT 549
>XP_006719205
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719204
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719203
          Length = 1091

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719202
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719201
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_006719200
          Length = 1126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MMTEMEGT 9
           +MT+++GT
Sbjct: 623 LMTQIQGT 630
>XP_005247237
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  MTEMEG 8
          MTEM+G
Sbjct: 91 MTEMQG 96
>XP_006713587
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   MTEMEG 8
           MTEM+G
Sbjct: 292 MTEMQG 297
>XP_005247233
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   MTEMEG 8
           MTEM+G
Sbjct: 261 MTEMQG 266
>XP_006713586
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   MTEMEG 8
           MTEM+G
Sbjct: 292 MTEMQG 297
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.122    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,844
Number of extensions: 510
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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