Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_361014                                                              19     869
NP_001243998                                                           19     869
NP_001661                                                              16    5631
NP_002838                                                              16    5631
NP_036587                                                              16    5631
XP_006724314                                                           16    5631
XP_006724313                                                           16    5631
XP_006724312                                                           16    5631
XP_006724311                                                           16    5631
XP_006724310                                                           16    5631
XP_006724309                                                           16    5631
XP_005261301                                                           16    5631
XP_006724308                                                           16    5631
XP_005261300                                                           16    5631
XP_006724307                                                           16    5631
XP_005261299                                                           16    5631
XP_006724306                                                           16    5631
XP_005261256                                                           16    5631
XP_005261255                                                           16    5631
XP_005261253                                                           16    5631
XP_005261252                                                           16    5631
XP_006716138                                                           16    5631
XP_006712455                                                           16    5631
XP_005263691                                                           16    5631
NP_570857                                                              16    5631
NP_570858                                                              16    5631
NP_003672                                                              16    5631
NP_714922                                                              16    5631
NP_659570                                                              16    7355
XP_006715976                                                           16    7355
XP_006715975                                                           16    7355
NP_055384                                                              16    7355
NP_002308                                                              15    9605
NP_694979                                                              15    9605
NP_037491                                                              15    9605
NP_079303                                                              15    9605
NP_065166                                                              15    9605
NP_001273296                                                           15    9605
XP_006723895                                                           15    9605
XP_005259334                                                           15    9605
XP_005259333                                                           15    9605
XP_005259263                                                           15    9605
XP_005249715                                                           15    9605
XP_005249714                                                           15    9605
XP_006715730                                                           15    9605
NP_001035751                                                           15    9605
>NP_361014
          Length = 707

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LLSVGSQRR 9
          LLSVGS+RR
Sbjct: 5  LLSVGSKRR 13
>NP_001243998
          Length = 176

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LLSVGSQRR 9
          LLSVGS+RR
Sbjct: 5  LLSVGSKRR 13
>NP_001661
          Length = 962

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>NP_002838
          Length = 1015

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           SVGS+RR
Sbjct: 132 SVGSERR 138
>NP_036587
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 902 AVGSQRR 908
>XP_006724314
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_006724313
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_006724312
          Length = 667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_006724311
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 540 AVGSQRR 546
>XP_006724310
          Length = 899

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 540 AVGSQRR 546
>XP_006724309
          Length = 922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 521 AVGSQRR 527
>XP_005261301
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_006724308
          Length = 935

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_005261300
          Length = 956

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_006724307
          Length = 986

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_005261299
          Length = 998

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_006724306
          Length = 1004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 603 AVGSQRR 609
>XP_005261256
          Length = 239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSVGSQRR 9
           L+ +GSQRR
Sbjct: 126 LIVLGSQRR 134
>XP_005261255
          Length = 272

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSVGSQRR 9
           L+ +GSQRR
Sbjct: 159 LIVLGSQRR 167
>XP_005261253
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSVGSQRR 9
           L+ +GSQRR
Sbjct: 208 LIVLGSQRR 216
>XP_005261252
          Length = 364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSVGSQRR 9
           L+ +GSQRR
Sbjct: 251 LIVLGSQRR 259
>XP_006716138
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           SVGS+RR
Sbjct: 132 SVGSERR 138
>XP_006712455
          Length = 1055

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 901 AVGSQRR 907
>XP_005263691
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           +VGSQRR
Sbjct: 902 AVGSQRR 908
>NP_570857
          Length = 998

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           SVGS+RR
Sbjct: 115 SVGSERR 121
>NP_570858
          Length = 986

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVGSQRR 9
           SVGS+RR
Sbjct: 132 SVGSERR 138
>NP_003672
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSVGSQRR 9
           L+ +GSQRR
Sbjct: 199 LIVLGSQRR 207
>NP_714922
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLSVGSQR 8
          LL+VGS+R
Sbjct: 25 LLTVGSER 32
>NP_659570
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSVGSQR 8
           LLS GSQ+
Sbjct: 206 LLSTGSQK 213
>XP_006715976
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSVGSQR 8
           LLS GSQ+
Sbjct: 206 LLSTGSQK 213
>XP_006715975
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSVGSQR 8
           LLS GSQ+
Sbjct: 206 LLSTGSQK 213
>NP_055384
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSVGSQR 8
           LLS GSQ+
Sbjct: 206 LLSTGSQK 213
>NP_002308
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LLSVGSQ 7
          LLS+GSQ
Sbjct: 57 LLSLGSQ 63
>NP_694979
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SVGSQR 8
         SVGSQR
Sbjct: 3 SVGSQR 8
>NP_037491
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LLSVGSQ 7
          LLSVG+Q
Sbjct: 66 LLSVGNQ 72
>NP_079303
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSVGSQ 7
           LLSVG+Q
Sbjct: 98  LLSVGNQ 104
>NP_065166
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SVGSQR 8
           SVGSQR
Sbjct: 238 SVGSQR 243
>NP_001273296
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSVGSQRR 9
           LLS+GS+ R
Sbjct: 526 LLSLGSRTR 534
>XP_006723895
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SVGSQR 8
           SVGSQR
Sbjct: 238 SVGSQR 243
>XP_005259334
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LLSVGSQ 7
          LLSVG+Q
Sbjct: 8  LLSVGNQ 14
>XP_005259333
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSVGSQ 7
           LLSVG+Q
Sbjct: 98  LLSVGNQ 104
>XP_005259263
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LLSVGSQ 7
          LLSVG+Q
Sbjct: 66 LLSVGNQ 72
>XP_005249715
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SVGSQR 8
         SVGSQR
Sbjct: 3 SVGSQR 8
>XP_005249714
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SVGSQR 8
         SVGSQR
Sbjct: 3 SVGSQR 8
>XP_006715730
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SVGSQR 8
         SVGSQR
Sbjct: 3 SVGSQR 8
>NP_001035751
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3 SVGSQR 8
         SVGSQR
Sbjct: 3 SVGSQR 8
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.135    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 485,378
Number of extensions: 691
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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