Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              18    1482
NP_009297                                                              18    1482
NP_000351                                                              16    5631
NP_954986                                                              16    5631
NP_954987                                                              16    5631
NP_001243415                                                           16    7355
NP_001243417                                                           16    7355
NP_004478                                                              16    7355
NP_001243416                                                           16    7355
XP_006713654                                                           16    7355
XP_006713653                                                           16    7355
XP_005247430                                                           16    7355
XP_005247429                                                           16    7355
XP_006713652                                                           16    7355
XP_006713651                                                           16    7355
XP_006713650                                                           16    7355
XP_005247428                                                           16    7355
NP_075054                                                              16    7355
NP_258443                                                              15    9605
>NP_005148
          Length = 1130

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLSSVKQIS 9
            LLSSVK+IS
Sbjct: 1117 LLSSVKEIS 1125
>NP_009297
          Length = 1149

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLSSVKQIS 9
            LLSSVK+IS
Sbjct: 1136 LLSSVKEIS 1144
>NP_000351
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS V+Q+S
Sbjct: 144 LLSGVRQVS 152
>NP_954986
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS V+Q+S
Sbjct: 175 LLSGVRQVS 183
>NP_954987
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS V+Q+S
Sbjct: 171 LLSGVRQVS 179
>NP_001243415
          Length = 3269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 754 LLSQVKELS 762
>NP_001243417
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 674 LLSQVKELS 682
>NP_004478
          Length = 3259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 749 LLSQVKELS 757
>NP_001243416
          Length = 3225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 715 LLSQVKELS 723
>XP_006713654
          Length = 3189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 674 LLSQVKELS 682
>XP_006713653
          Length = 3223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 713 LLSQVKELS 721
>XP_005247430
          Length = 3228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 713 LLSQVKELS 721
>XP_005247429
          Length = 3230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 715 LLSQVKELS 723
>XP_006713652
          Length = 3263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 748 LLSQVKELS 756
>XP_006713651
          Length = 3264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 749 LLSQVKELS 757
>XP_006713650
          Length = 3264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 754 LLSQVKELS 762
>XP_005247428
          Length = 3269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLS VK++S
Sbjct: 754 LLSQVKELS 762
>NP_075054
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           LLSS+KQ S
Sbjct: 142 LLSSLKQSS 150
>NP_258443
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLSSVKQIS 9
           +LSSV QIS
Sbjct: 705 VLSSVVQIS 713
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.120    0.253 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 273,257
Number of extensions: 246
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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