Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_001171633                                                           17    4312
NP_003909                                                              17    4312
NP_001171632                                                           17    4312
NP_001073324                                                           17    4312
NP_001171631                                                           17    4312
NP_001009921                                                           17    4312
XP_005274679                                                           17    4312
XP_005274678                                                           17    4312
XP_006724585                                                           17    4312
XP_006724584                                                           17    4312
XP_005274676                                                           17    4312
XP_005274674                                                           17    4312
XP_005274675                                                           17    4312
XP_006713619                                                           17    4312
XP_005247308                                                           17    4312
NP_056118                                                              17    4312
NP_004563                                                              16    5631
NP_065188                                                              16    5631
NP_001005242                                                           16    5631
NP_001027566                                                           16    5631
NP_001027567                                                           16    5631
NP_940971                                                              16    5631
NP_001182033                                                           16    5631
NP_001182032                                                           16    5631
NP_001182031                                                           16    5631
NP_000628                                                              16    5631
NP_775894                                                              16    5631
NP_001124390                                                           16    5631
NP_112494                                                              16    5631
XP_005261936                                                           16    5631
XP_005261935                                                           16    5631
XP_005261934                                                           16    5631
XP_005261933                                                           16    5631
XP_006721893                                                           16    5631
XP_006721892                                                           16    5631
XP_006721891                                                           16    5631
XP_006721890                                                           16    5631
XP_005267118                                                           16    5631
XP_006715581                                                           16    5631
XP_006715580                                                           16    5631
XP_006715579                                                           16    5631
XP_006714171                                                           16    5631
NP_055691                                                              16    5631
NP_004975                                                              16    7355
NP_115927                                                              16    7355
NP_056164                                                              16    7355
NP_001264282                                                           16    7355
NP_006442                                                              16    7355
NP_071373                                                              16    7355
NP_899152                                                              16    7355
NP_877590                                                              16    7355
NP_775922                                                              16    7355
XP_006715292                                                           16    7355
XP_005249030                                                           16    7355
XP_005249029                                                           16    7355
XP_005266015                                                           16    7355
XP_005248287                                                           16    7355
NP_061974                                                              15    9605
NP_001138897                                                           15    9605
NP_004514                                                              15    9605
NP_114480                                                              15    9605
NP_005117                                                              15    9605
NP_005946                                                              15    9605
NP_114481                                                              15    9605
NP_061737                                                              15    9605
NP_036569                                                              15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LNSIFQNS 9
            LNSIFQNS
Sbjct: 2275 LNSIFQNS 2282
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LNSIFQNS 9
            LNSIFQNS
Sbjct: 2070 LNSIFQNS 2077
>NP_001171633
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLNSIFQN 8
          LLNS F+N
Sbjct: 13 LLNSFFRN 20
>NP_003909
          Length = 501

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 199 LLNSFFRN 206
>NP_001171632
          Length = 430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 199 LLNSFFRN 206
>NP_001073324
          Length = 470

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 168 LLNSFFRN 175
>NP_001171631
          Length = 469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 168 LLNSFFRN 175
>NP_001009921
          Length = 1428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    NSIFQN 8
            NSIFQN
Sbjct: 1408 NSIFQN 1413
>XP_005274679
          Length = 489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 168 LLNSFFRN 175
>XP_005274678
          Length = 489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 168 LLNSFFRN 175
>XP_006724585
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 197 LLNSFFRN 204
>XP_006724584
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 199 LLNSFFRN 206
>XP_005274676
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 199 LLNSFFRN 206
>XP_005274674
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 199 LLNSFFRN 206
>XP_005274675
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLNS F+N
Sbjct: 199 LLNSFFRN 206
>XP_006713619
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NSIFQN 8
           NSIFQN
Sbjct: 836 NSIFQN 841
>XP_005247308
          Length = 1428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    NSIFQN 8
            NSIFQN
Sbjct: 1408 NSIFQN 1413
>NP_056118
          Length = 1426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    NSIFQN 8
            NSIFQN
Sbjct: 1406 NSIFQN 1411
>NP_004563
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LNSIFQNS 9
           LN+I QNS
Sbjct: 799 LNNIIQNS 806
>NP_065188
          Length = 1221

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 437 LNSTFQN 443
>NP_001005242
          Length = 837

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LNSIFQNS 9
           LN+I QNS
Sbjct: 755 LNNIIQNS 762
>NP_001027566
          Length = 1193

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 409 LNSTFQN 415
>NP_001027567
          Length = 1222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 409 LNSTFQN 415
>NP_940971
          Length = 1250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 437 LNSTFQN 443
>NP_001182033
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LNSIFQNS 9
           LN+I+QN+
Sbjct: 154 LNAIYQNN 161
>NP_001182032
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LNSIFQNS 9
           LN+I+QN+
Sbjct: 154 LNAIYQNN 161
>NP_001182031
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LNSIFQNS 9
           LN+I+QN+
Sbjct: 154 LNAIYQNN 161
>NP_000628
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LNSIFQNS 9
           LN+I+QN+
Sbjct: 154 LNAIYQNN 161
>NP_775894
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NSIFQNS 9
           NS+FQN+
Sbjct: 206 NSLFQNT 212
>NP_001124390
          Length = 891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NSIFQNS 9
           NS+FQN+
Sbjct: 513 NSLFQNT 519
>NP_112494
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           +LN +FQN
Sbjct: 425 ILNCLFQN 432
>XP_005261936
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LNSIFQNS 9
          LN++FQ+S
Sbjct: 41 LNNVFQDS 48
>XP_005261935
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LNSIFQNS 9
          LN++FQ+S
Sbjct: 41 LNNVFQDS 48
>XP_005261934
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LNSIFQNS 9
          LN++FQ+S
Sbjct: 41 LNNVFQDS 48
>XP_005261933
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LNSIFQNS 9
          LN++FQ+S
Sbjct: 41 LNNVFQDS 48
>XP_006721893
          Length = 713

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NSIFQNS 9
           NS+FQN+
Sbjct: 513 NSLFQNT 519
>XP_006721892
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NSIFQNS 9
           NS+FQN+
Sbjct: 465 NSLFQNT 471
>XP_006721891
          Length = 891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NSIFQNS 9
           NS+FQN+
Sbjct: 513 NSLFQNT 519
>XP_006721890
          Length = 891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NSIFQNS 9
           NS+FQN+
Sbjct: 513 NSLFQNT 519
>XP_005267118
          Length = 1222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 438 LNSTFQN 444
>XP_006715581
          Length = 1223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 410 LNSTFQN 416
>XP_006715580
          Length = 1249

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 436 LNSTFQN 442
>XP_006715579
          Length = 1251

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS FQN
Sbjct: 438 LNSTFQN 444
>XP_006714171
          Length = 206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLNSIFQNS 9
           LLN IFQ +
Sbjct: 162 LLNDIFQRN 170
>NP_055691
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LNSIFQNS 9
          LN++FQ+S
Sbjct: 41 LNNVFQDS 48
>NP_004975
          Length = 1032

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NSIFQN 8
           NS+FQN
Sbjct: 948 NSLFQN 953
>NP_115927
          Length = 1321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLNSIFQNS 9
           L+ S+F+NS
Sbjct: 288 LIMSVFENS 296
>NP_056164
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  NSIFQNS 9
          NSIF NS
Sbjct: 46 NSIFANS 52
>NP_001264282
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LLNSIFQ 7
           LLN IFQ
Sbjct: 320 LLNDIFQ 326
>NP_006442
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLN++F N
Sbjct: 303 LLNALFSN 310
>NP_071373
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLNSIFQNS 9
          L NS+F N+
Sbjct: 32 LCNSVFSNA 40
>NP_899152
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLN++F N
Sbjct: 191 LLNALFSN 198
>NP_877590
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLN++F N
Sbjct: 224 LLNALFSN 231
>NP_775922
          Length = 6996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLNSIFQNS 9
            +LN IFQ++
Sbjct: 1873 ILNEIFQST 1881
>XP_006715292
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLNSIFQNS 9
           L+ S+F+NS
Sbjct: 275 LIMSVFENS 283
>XP_005249030
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  NSIFQNS 9
          NSIF NS
Sbjct: 46 NSIFANS 52
>XP_005249029
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  NSIFQNS 9
          NSIF NS
Sbjct: 46 NSIFANS 52
>XP_005266015
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLNSIFQNS 9
          L NS+F N+
Sbjct: 32 LCNSVFSNA 40
>XP_005248287
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLNSIFQN 8
           LLN++F N
Sbjct: 191 LLNALFSN 198
>NP_061974
          Length = 188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLNSIFQ 7
          +LNSI+Q
Sbjct: 16 ILNSIYQ 22
>NP_001138897
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLNSIFQNS 9
           LLNS+F+ S
Sbjct: 407 LLNSMFEFS 415
>NP_004514
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNSIFQN 8
           LNS+F N
Sbjct: 538 LNSLFNN 544
>NP_114480
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNSIFQNS 9
           +NSI +NS
Sbjct: 354 INSILENS 361
>NP_005117
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLNSIFQNS 9
           LLNS+F+ S
Sbjct: 482 LLNSMFEFS 490
>NP_005946
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLNSIFQNS 9
           +  S+FQNS
Sbjct: 370 IFESMFQNS 378
>NP_114481
          Length = 750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNSIFQNS 9
           +NSI +NS
Sbjct: 354 INSILENS 361
>NP_061737
          Length = 935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNSIFQNS 9
           +NSI +NS
Sbjct: 354 INSILENS 361
>NP_036569
          Length = 136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLNSIFQNS 9
           L+N+I QN+
Sbjct: 94  LVNNILQNA 102
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.132    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 437,525
Number of extensions: 798
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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