Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006726436                                                           18    1935
XP_006726410                                                           18    1935
XP_006711784                                                           18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
XP_006711164                                                           18    1935
XP_005276114                                                           18    1935
XP_006710122                                                           18    1935
NP_005362                                                              17    3301
XP_005268930                                                           17    3301
NP_001934                                                              17    4312
NP_001129243                                                           16    5631
NP_817123                                                              16    5631
NP_002942                                                              16    5631
XP_006723915                                                           16    5631
XP_006723914                                                           16    5631
XP_005260548                                                           16    5631
XP_006723913                                                           16    5631
XP_006723912                                                           16    5631
NP_001127925                                                           16    5631
NP_055931                                                              16    7355
NP_001157683                                                           16    7355
NP_001157685                                                           16    7355
NP_060788                                                              15    9605
NP_065944                                                              15    9605
NP_001277140                                                           15    9605
NP_001010855                                                           15    9605
NP_001077086                                                           15    9605
NP_055596                                                              15    9605
XP_005253473                                                           15    9605
XP_005253472                                                           15    9605
XP_005253471                                                           15    9605
XP_005253470                                                           15    9605
XP_006719168                                                           15    9605
XP_006719167                                                           15    9605
XP_006719166                                                           15    9605
XP_006716556                                                           15    9605
XP_006716555                                                           15    9605
XP_006716554                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2173 LLELRTKVS 2181
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2279 LLELRTKVS 2287
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2279 LLELRTKVS 2287
>XP_006726436
          Length = 178

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LLELRIKVS 9
          LLELR KVS
Sbjct: 57 LLELRTKVS 65
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2020 LLELRTKVS 2028
>XP_006711784
          Length = 178

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LLELRIKVS 9
          LLELR KVS
Sbjct: 57 LLELRTKVS 65
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2235 LLELRTKVS 2243
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 1286 LLELRTKVS 1294
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2235 LLELRTKVS 2243
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2344 LLELRTKVS 2352
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2278 LLELRTKVS 2286
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2279 LLELRTKVS 2287
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2282 LLELRTKVS 2290
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2323 LLELRTKVS 2331
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2332 LLELRTKVS 2340
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2344 LLELRTKVS 2352
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2345 LLELRTKVS 2353
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2442 LLELRTKVS 2450
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2442 LLELRTKVS 2450
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2362 LLELRTKVS 2370
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2442 LLELRTKVS 2450
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2403 LLELRTKVS 2411
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2442 LLELRTKVS 2450
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2441 LLELRTKVS 2449
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2442 LLELRTKVS 2450
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            LLELR KVS
Sbjct: 2020 LLELRTKVS 2028
>XP_005276114
          Length = 134

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LLELRIKVS 9
          LLELR KVS
Sbjct: 27 LLELRTKVS 35
>XP_006710122
          Length = 126

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LLELRIKVS 9
          LLELR KVS
Sbjct: 57 LLELRTKVS 65
>NP_005362
          Length = 276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+R+KVS
Sbjct: 106 LEIRVKVS 113
>XP_005268930
          Length = 233

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LELRIKVS 9
          LE+R+KVS
Sbjct: 63 LEIRVKVS 70
>NP_001934
          Length = 1118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LELRIKV 8
           LELRIKV
Sbjct: 143 LELRIKV 149
>NP_001129243
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +ELR+K+S
Sbjct: 331 VELRVKIS 338
>NP_817123
          Length = 1040

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LELRIKV 8
           LELR+KV
Sbjct: 141 LELRVKV 147
>NP_002942
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +ELR+K+S
Sbjct: 363 VELRVKIS 370
>XP_006723915
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>XP_006723914
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>XP_005260548
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +ELR+K+S
Sbjct: 363 VELRVKIS 370
>XP_006723913
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>XP_006723912
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +ELR+K+S
Sbjct: 379 VELRVKIS 386
>NP_001127925
          Length = 1059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LELRIKV 8
           LELR+KV
Sbjct: 141 LELRVKV 147
>NP_055931
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +E+R+KVS
Sbjct: 590 IEMRLKVS 597
>NP_001157683
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +E+R+KVS
Sbjct: 625 IEMRLKVS 632
>NP_001157685
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           +E+R+KVS
Sbjct: 590 IEMRLKVS 597
>NP_060788
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 141 LEIKLKVS 148
>NP_065944
          Length = 1701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LLELRIKV 8
            L+ELRI++
Sbjct: 1439 LIELRIQI 1446
>NP_001277140
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LLELRIKV 8
           L+EL++K+
Sbjct: 422 LIELKVKI 429
>NP_001010855
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LLELRIKV 8
           L+EL++K+
Sbjct: 558 LIELKVKI 565
>NP_001077086
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            L EL++KVS
Sbjct: 1043 LQELKLKVS 1051
>NP_055596
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            L EL++KVS
Sbjct: 1043 LQELKLKVS 1051
>XP_005253473
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 111 LEIKLKVS 118
>XP_005253472
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 111 LEIKLKVS 118
>XP_005253471
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 141 LEIKLKVS 148
>XP_005253470
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 141 LEIKLKVS 148
>XP_006719168
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 141 LEIKLKVS 148
>XP_006719167
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 141 LEIKLKVS 148
>XP_006719166
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LELRIKVS 9
           LE+++KVS
Sbjct: 149 LEIKLKVS 156
>XP_006716556
          Length = 1048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLELRIKVS 9
           L EL++KVS
Sbjct: 500 LQELKLKVS 508
>XP_006716555
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLELRIKVS 9
           L EL++KVS
Sbjct: 991 LQELKLKVS 999
>XP_006716554
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LLELRIKVS 9
            L EL++KVS
Sbjct: 1043 LQELKLKVS 1051
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.148    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 395,760
Number of extensions: 486
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package