Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              19     869
NP_055731                                                              17    3301
NP_004163                                                              16    5631
NP_001160167                                                           16    5631
NP_001276868                                                           16    5631
NP_001276869                                                           16    5631
NP_001092289                                                           16    5631
NP_000914                                                              16    5631
NP_001092288                                                           16    5631
XP_006714551                                                           16    5631
XP_005248399                                                           16    5631
NP_001136024                                                           16    7355
NP_689785                                                              16    7355
NP_000916                                                              16    7355
NP_001166939                                                           16    7355
NP_689652                                                              16    7355
NP_116124                                                              16    7355
NP_001269542                                                           16    7355
NP_065928                                                              16    7355
NP_004552                                                              16    7355
XP_005256527                                                           16    7355
XP_006719318                                                           16    7355
XP_006719317                                                           16    7355
XP_006719316                                                           16    7355
XP_006719315                                                           16    7355
XP_006719314                                                           16    7355
XP_005274075                                                           16    7355
XP_005274074                                                           16    7355
XP_006717028                                                           16    7355
XP_006717027                                                           16    7355
XP_005272226                                                           16    7355
XP_006712324                                                           16    7355
XP_005246344                                                           16    7355
NP_694453                                                              16    7355
NP_001239268                                                           15    9605
NP_001239267                                                           15    9605
NP_001785                                                              15    9605
NP_653206                                                              15    9605
NP_001438                                                              15    9605
NP_001005415                                                           15    9605
NP_001147930                                                           15    9605
XP_006726196                                                           15    9605
XP_005275679                                                           15    9605
XP_005275678                                                           15    9605
XP_005275677                                                           15    9605
XP_006726007                                                           15    9605
XP_005275375                                                           15    9605
XP_005275374                                                           15    9605
XP_005275373                                                           15    9605
XP_006725811                                                           15    9605
XP_005275118                                                           15    9605
XP_005275117                                                           15    9605
XP_005275116                                                           15    9605
XP_006725592                                                           15    9605
XP_005272963                                                           15    9605
XP_005272962                                                           15    9605
XP_005272961                                                           15    9605
XP_006725113                                                           15    9605
XP_005274953                                                           15    9605
XP_005274952                                                           15    9605
XP_005274951                                                           15    9605
XP_006722826                                                           15    9605
XP_006722825                                                           15    9605
XP_005257009                                                           15    9605
XP_006720910                                                           15    9605
XP_006720909                                                           15    9605
XP_006715283                                                           15    9605
XP_005249486                                                           15    9605
XP_005249485                                                           15    9605
XP_005249484                                                           15    9605
XP_006714824                                                           15    9605
NP_001005416                                                           15    9605
NP_057580                                                              15    9605
NP_079534                                                              15    9605
>NP_004351
          Length = 882

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LKVTAADAP 9
           LKVT ADAP
Sbjct: 396 LKVTDADAP 404
>NP_055731
          Length = 1503

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LKVTAADAP 9
            LK TAA+AP
Sbjct: 1334 LKPTAANAP 1342
>NP_004163
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKVTAADA 8
           ++VTAADA
Sbjct: 162 VRVTAADA 169
>NP_001160167
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKVTAADA 8
           ++VTAADA
Sbjct: 162 VRVTAADA 169
>NP_001276868
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKVTAADA 8
           ++VTAADA
Sbjct: 116 VRVTAADA 123
>NP_001276869
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKVTAADA 8
           ++VTAADA
Sbjct: 162 VRVTAADA 169
>NP_001092289
          Length = 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KVTAADAP 9
           KVTA +AP
Sbjct: 171 KVTAEEAP 178
>NP_000914
          Length = 712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KVTAADAP 9
           KVTA +AP
Sbjct: 277 KVTAEEAP 284
>NP_001092288
          Length = 680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KVTAADAP 9
           KVTA +AP
Sbjct: 245 KVTAEEAP 252
>XP_006714551
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKVTAADA 8
           ++VTAADA
Sbjct: 162 VRVTAADA 169
>XP_005248399
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKVTAADA 8
           ++VTAADA
Sbjct: 162 VRVTAADA 169
>NP_001136024
          Length = 1369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LKVTAADA 8
           L+VTA+DA
Sbjct: 683 LQVTASDA 690
>NP_689785
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LKV +AD P
Sbjct: 237 LKVISADQP 245
>NP_000916
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VT AD P
Sbjct: 323 VRVTGADVP 331
>NP_001166939
          Length = 341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VT AD P
Sbjct: 305 VRVTGADVP 313
>NP_689652
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 292 ITAAEAP 298
>NP_116124
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 505 ITAAEAP 511
>NP_001269542
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 399 ITAAEAP 405
>NP_065928
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KVTAADAP 9
            K+T+ DAP
Sbjct: 2014 KLTSVDAP 2021
>NP_004552
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           +KVT  D+P
Sbjct: 105 MKVTLGDSP 113
>XP_005256527
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KVTAADAP 9
            K+T+ DAP
Sbjct: 2014 KLTSVDAP 2021
>XP_006719318
          Length = 506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 343 ITAAEAP 349
>XP_006719317
          Length = 540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 377 ITAAEAP 383
>XP_006719316
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 399 ITAAEAP 405
>XP_006719315
          Length = 590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 427 ITAAEAP 433
>XP_006719314
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTAADAP 9
           +TAA+AP
Sbjct: 498 ITAAEAP 504
>XP_005274075
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LKVTAADAP 9
          +KVT  D+P
Sbjct: 43 MKVTLGDSP 51
>XP_005274074
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LKVTAADAP 9
          +KVT  D+P
Sbjct: 43 MKVTLGDSP 51
>XP_006717028
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LKV +AD P
Sbjct: 165 LKVISADQP 173
>XP_006717027
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LKV +AD P
Sbjct: 192 LKVISADQP 200
>XP_005272226
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LKV +AD P
Sbjct: 249 LKVISADQP 257
>XP_006712324
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LKV  AD+P
Sbjct: 457 LKVMLADSP 465
>XP_005246344
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LKV  AD+P
Sbjct: 457 LKVMLADSP 465
>NP_694453
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LKV  AD+P
Sbjct: 455 LKVMLADSP 463
>NP_001239268
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKVTAADA 8
           + +TAADA
Sbjct: 557 INITAADA 564
>NP_001239267
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKVTAADA 8
           + +TAADA
Sbjct: 594 INITAADA 601
>NP_001785
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKVTAADA 8
           + +TAADA
Sbjct: 631 INITAADA 638
>NP_653206
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVTAADAP 9
           LK+T  D P
Sbjct: 106 LKLTVTDTP 114
>NP_001438
          Length = 4349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKVTAAD 7
           LK+TA+D
Sbjct: 638 LKITASD 644
>NP_001005415
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LK+  AD+P
Sbjct: 216 LKIREADSP 224
>NP_001147930
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVTAADAP 9
           LK+T  D P
Sbjct: 106 LKLTVTDTP 114
>XP_006726196
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 560 IQVTAEDTP 568
>XP_005275679
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005275678
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005275677
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_006726007
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 560 IQVTAEDTP 568
>XP_005275375
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005275374
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005275373
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_006725811
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 560 IQVTAEDTP 568
>XP_005275118
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005275117
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005275116
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_006725592
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 560 IQVTAEDTP 568
>XP_005272963
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005272962
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005272961
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_006725113
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 560 IQVTAEDTP 568
>XP_005274953
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005274952
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005274951
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_006722826
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LK+  AD+P
Sbjct: 146 LKIREADSP 154
>XP_006722825
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LK+  AD+P
Sbjct: 216 LKIREADSP 224
>XP_005257009
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LKVTAADAP 9
          ++VTA D P
Sbjct: 11 VQVTAGDTP 19
>XP_006720910
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVTAADAP 9
           LK+T  D P
Sbjct: 106 LKLTVTDTP 114
>XP_006720909
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LKVTAADAP 9
           LK+T  D P
Sbjct: 106 LKLTVTDTP 114
>XP_006715283
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 560 IQVTAEDTP 568
>XP_005249486
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005249485
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_005249484
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
>XP_006714824
          Length = 4349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LKVTAAD 7
           LK+TA+D
Sbjct: 638 LKITASD 644
>NP_001005416
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LK+  AD+P
Sbjct: 146 LKIREADSP 154
>NP_057580
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           LK+  AD+P
Sbjct: 216 LKIREADSP 224
>NP_079534
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKVTAADAP 9
           ++VTA D P
Sbjct: 583 IQVTAEDTP 591
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.120    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 337,568
Number of extensions: 574
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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