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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     509
XP_006718907                                                           20     509
XP_006718906                                                           20     509
XP_005271619                                                           20     509
XP_005271618                                                           20     509
NP_078966                                                              17    4312
XP_006723004                                                           17    4312
NP_647479                                                              16    7355
NP_758963                                                              16    7355
NP_078930                                                              16    7355
NP_055184                                                              16    7355
NP_001135842                                                           16    7355
NP_005427                                                              16    7355
XP_006712480                                                           16    7355
XP_006712479                                                           16    7355
XP_006712478                                                           16    7355
NP_005319                                                              15    9605
NP_443137                                                              15    9605
NP_001186209                                                           15    9605
NP_005320                                                              15    9605
NP_056169                                                              15    9605
NP_001094064                                                           15    9605
NP_079040                                                              15    9605
NP_060549                                                              15    9605
NP_060189                                                              15    9605
XP_005255978                                                           15    9605
XP_005255977                                                           15    9605
XP_005265303                                                           15    9605
XP_005265302                                                           15    9605
XP_005246323                                                           15    9605
XP_005246322                                                           15    9605
XP_006712291                                                           15    9605
XP_005246320                                                           15    9605
XP_005264455                                                           15    9605

>NP_000042
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LKTLAVNFQ 9
           LKTLAVNF+
Sbjct: 240 LKTLAVNFR 248



>XP_006718907
          Length = 3050

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LKTLAVNFQ 9
           LKTLAVNF+
Sbjct: 240 LKTLAVNFR 248



>XP_006718906
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LKTLAVNFQ 9
           LKTLAVNF+
Sbjct: 240 LKTLAVNFR 248



>XP_005271619
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LKTLAVNFQ 9
           LKTLAVNF+
Sbjct: 240 LKTLAVNFR 248



>XP_005271618
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LKTLAVNFQ 9
           LKTLAVNF+
Sbjct: 240 LKTLAVNFR 248



>NP_078966
          Length = 14507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1     LKTLAVNF 8
             LKTL +NF
Sbjct: 14074 LKTLTLNF 14081



>XP_006723004
          Length = 6443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LKTLAVNF 8
            LKTL +NF
Sbjct: 6010 LKTLTLNF 6017



>NP_647479
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKTLAVNFQ 9
           L+ LAV FQ
Sbjct: 559 LRALAVEFQ 567



>NP_758963
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKTLAVNFQ 9
           L+ LAV FQ
Sbjct: 559 LRALAVEFQ 567



>NP_078930
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LKTLAVNF 8
           LKT  VNF
Sbjct: 227 LKTATVNF 234



>NP_055184
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKTLAVNFQ 9
           L+TL V FQ
Sbjct: 173 LRTLKVTFQ 181



>NP_001135842
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LKTLAVNFQ 9
          L+TL V FQ
Sbjct: 66 LRTLKVTFQ 74



>NP_005427
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KTLAVNFQ 9
           +TLAVN++
Sbjct: 128 ETLAVNYE 135



>XP_006712480
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKTLAVNFQ 9
           L+TL V FQ
Sbjct: 173 LRTLKVTFQ 181



>XP_006712479
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LKTLAVNFQ 9
          L+TL V FQ
Sbjct: 66 LRTLKVTFQ 74



>XP_006712478
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKTLAVNFQ 9
           L+TL V FQ
Sbjct: 160 LRTLKVTFQ 168



>NP_005319
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTLAVNF 8
           KT+ VNF
Sbjct: 469 KTIVVNF 475



>NP_443137
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKTLAVNF 8
           LKTL V+F
Sbjct: 725 LKTLPVDF 732



>NP_001186209
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTLAVNF 8
           KT+ VNF
Sbjct: 472 KTIVVNF 478



>NP_005320
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTLAVNF 8
           KT+ VNF
Sbjct: 472 KTIVVNF 478



>NP_056169
          Length = 1749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    LKTLAVNF 8
            LKTL  NF
Sbjct: 1408 LKTLRYNF 1415



>NP_001094064
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTLAVNFQ 9
           KT++VN Q
Sbjct: 738 KTISVNIQ 745



>NP_079040
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LKTLAVNFQ 9
           +KTL +N++
Sbjct: 862 IKTLPINYR 870



>NP_060549
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKTLAVNF 8
           +KTL +NF
Sbjct: 581 IKTLLLNF 588



>NP_060189
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTLAVNFQ 9
           KT++VN Q
Sbjct: 738 KTISVNIQ 745



>XP_005255978
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTLAVNF 8
           KT+ VNF
Sbjct: 472 KTIVVNF 478



>XP_005255977
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTLAVNF 8
           KT+ VNF
Sbjct: 472 KTIVVNF 478



>XP_005265303
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTLAVNFQ 9
           KT++VN Q
Sbjct: 738 KTISVNIQ 745



>XP_005265302
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTLAVNFQ 9
           KT++VN Q
Sbjct: 738 KTISVNIQ 745



>XP_005246323
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKTLAVNF 8
           LKTL V+F
Sbjct: 725 LKTLPVDF 732



>XP_005246322
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKTLAVNF 8
           LKTL V+F
Sbjct: 725 LKTLPVDF 732



>XP_006712291
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKTLAVNF 8
           LKTL V+F
Sbjct: 725 LKTLPVDF 732



>XP_005246320
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKTLAVNF 8
           LKTL V+F
Sbjct: 725 LKTLPVDF 732



>XP_005264455
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LKTLAVNF 8
           +KTL +NF
Sbjct: 581 IKTLLLNF 588



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.135    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,603
Number of extensions: 491
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)