Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_073624                                                              16    5631
NP_004496                                                              16    5631
XP_005256902                                                           16    5631
XP_006710887                                                           16    5631
NP_001273538                                                           16    7355
NP_115507                                                              16    7355
NP_001137391                                                           16    7355
NP_858043                                                              16    7355
NP_001177755                                                           16    7355
NP_001177756                                                           16    7355
XP_005260566                                                           16    7355
XP_006715637                                                           16    7355
XP_005267214                                                           16    7355
XP_005267213                                                           16    7355
XP_006715636                                                           16    7355
XP_005267212                                                           16    7355
XP_005267211                                                           16    7355
NP_071389                                                              16    7355
NP_001073881                                                           15    9605
NP_005420                                                              15    9605
NP_001114                                                              15    9605
NP_006712                                                              15    9605
NP_001189379                                                           15    9605
NP_001189378                                                           15    9605
NP_001139146                                                           15    9605
NP_066547                                                              15    9605
NP_078964                                                              15    9605
NP_803879                                                              15    9605
NP_803881                                                              15    9605
NP_001257700                                                           15    9605
NP_001258992                                                           15    9605
NP_110428                                                              15    9605
NP_001229291                                                           15    9605
NP_689483                                                              15    9605
NP_001098060                                                           15    9605
NP_001098059                                                           15    9605
NP_001098058                                                           15    9605
NP_001098057                                                           15    9605
NP_001258991                                                           15    9605
NP_001092270                                                           15    9605
NP_001258990                                                           15    9605
XP_006724671                                                           15    9605
XP_006724670                                                           15    9605
XP_005258125                                                           15    9605
XP_006722234                                                           15    9605
XP_005269595                                                           15    9605
XP_005252650                                                           15    9605
XP_006717569                                                           15    9605
XP_006717568                                                           15    9605
XP_006717567                                                           15    9605
XP_006713622                                                           15    9605
XP_005247320                                                           15    9605
XP_005247319                                                           15    9605
XP_005247318                                                           15    9605
XP_005247315                                                           15    9605
XP_005247314                                                           15    9605
XP_005247313                                                           15    9605
XP_005247312                                                           15    9605
NP_077289                                                              15    9605
>NP_073624
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KTKA+P++
Sbjct: 144 KTKAVPKV 151
>NP_004496
          Length = 1406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKTKAMPRL 9
           L+ K+MPRL
Sbjct: 449 LEWKSMPRL 457
>XP_005256902
          Length = 1406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LKTKAMPRL 9
           L+ K+MPRL
Sbjct: 449 LEWKSMPRL 457
>XP_006710887
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KTKA+P++
Sbjct: 144 KTKAVPKV 151
>NP_001273538
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LKTKAMPR 8
          L+TKA+P+
Sbjct: 80 LQTKAVPK 87
>NP_115507
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKTKAMPR 8
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252
>NP_001137391
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKTKAMPR 8
           L+TKAM R
Sbjct: 128 LRTKAMAR 135
>NP_858043
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKTKAMPR 8
           L+TKAM R
Sbjct: 128 LRTKAMAR 135
>NP_001177755
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+PR+
Sbjct: 167 KTEAVPRV 174
>NP_001177756
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KTKAMPRL 9
          KT+A+PR+
Sbjct: 10 KTEAVPRV 17
>XP_005260566
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+PR+
Sbjct: 167 KTEAVPRV 174
>XP_006715637
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LKTKAMPR 8
          L+TKA+P+
Sbjct: 80 LQTKAVPK 87
>XP_005267214
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LKTKAMPR 8
          L+TKA+P+
Sbjct: 80 LQTKAVPK 87
>XP_005267213
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKTKAMPR 8
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252
>XP_006715636
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKTKAMPR 8
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252
>XP_005267212
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKTKAMPR 8
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252
>XP_005267211
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LKTKAMPR 8
           L+TKA+P+
Sbjct: 245 LQTKAVPK 252
>NP_071389
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+PR+
Sbjct: 167 KTEAVPRV 174
>NP_001073881
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 975 ETKEMPKL 982
>NP_005420
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTKAMPR 8
           KT+ MPR
Sbjct: 128 KTQCMPR 134
>NP_001114
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+P++
Sbjct: 247 KTQALPKM 254
>NP_006712
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+P++
Sbjct: 264 KTQALPKM 271
>NP_001189379
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+P++
Sbjct: 207 KTQALPKM 214
>NP_001189378
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+P++
Sbjct: 229 KTQALPKM 236
>NP_001139146
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           K+K+MP L
Sbjct: 423 KSKSMPNL 430
>NP_066547
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           K+K+MP L
Sbjct: 519 KSKSMPNL 526
>NP_078964
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTKAMPR 8
           KTK +PR
Sbjct: 115 KTKKLPR 121
>NP_803879
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>NP_803881
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>NP_001257700
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           K+K+MP L
Sbjct: 619 KSKSMPNL 626
>NP_001258992
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>NP_110428
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>NP_001229291
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>NP_689483
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKTKAMPRL 9
           LKTK  P++
Sbjct: 152 LKTKRKPKI 160
>NP_001098060
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKTKAMPRL 9
           LKTK  P++
Sbjct: 152 LKTKRKPKI 160
>NP_001098059
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKTKAMPRL 9
           LKTK  P++
Sbjct: 152 LKTKRKPKI 160
>NP_001098058
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKTKAMPRL 9
           LKTK  P++
Sbjct: 152 LKTKRKPKI 160
>NP_001098057
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKTKAMPRL 9
           LKTK  P++
Sbjct: 152 LKTKRKPKI 160
>NP_001258991
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>NP_001092270
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>NP_001258990
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>XP_006724671
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>XP_006724670
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTKAMPRL 9
           KTK  PRL
Sbjct: 495 KTKDTPRL 502
>XP_005258125
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKTKAMPRL 9
           LKTK  P++
Sbjct: 152 LKTKRKPKI 160
>XP_006722234
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKTKAMPRL 9
           LKTK  P++
Sbjct: 152 LKTKRKPKI 160
>XP_005269595
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KTKAMPRL 9
           KT+A+P++
Sbjct: 264 KTQALPKM 271
>XP_005252650
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTKAMPR 8
           KTK +PR
Sbjct: 115 KTKKLPR 121
>XP_006717569
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTKAMPR 8
           KTK +PR
Sbjct: 701 KTKKLPR 707
>XP_006717568
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTKAMPR 8
           KTK +PR
Sbjct: 737 KTKKLPR 743
>XP_006717567
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   KTKAMPR 8
           KTK +PR
Sbjct: 808 KTKKLPR 814
>XP_006713622
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 975 ETKEMPKL 982
>XP_005247320
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 975 ETKEMPKL 982
>XP_005247319
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 975 ETKEMPKL 982
>XP_005247318
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 975 ETKEMPKL 982
>XP_005247315
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 975 ETKEMPKL 982
>XP_005247314
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 975 ETKEMPKL 982
>XP_005247313
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KTKAMPRL 9
           +TK MP+L
Sbjct: 976 ETKEMPKL 983
>XP_005247312
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    KTKAMPRL 9
            +TK MP+L
Sbjct: 1011 ETKEMPKL 1018
>NP_077289
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   TKAMPR 8
           TKA+PR
Sbjct: 145 TKALPR 150
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.132    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 536,448
Number of extensions: 875
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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