Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001001557                                                           19     665
NP_689707                                                              17    2528
NP_001137159                                                           17    2528
NP_061881                                                              17    3301
NP_004806                                                              17    4312
XP_006711111                                                           17    4312
NP_114113                                                              16    7355
NP_004729                                                              16    7355
NP_775864                                                              16    7355
NP_001230166                                                           16    7355
XP_006723951                                                           16    7355
XP_005260860                                                           16    7355
XP_005260859                                                           16    7355
XP_005260858                                                           16    7355
XP_005260857                                                           16    7355
XP_006723671                                                           16    7355
XP_006723670                                                           16    7355
XP_005260854                                                           16    7355
XP_006723669                                                           16    7355
XP_006719018                                                           16    7355
XP_006719016                                                           16    7355
XP_006719015                                                           16    7355
XP_005251183                                                           16    7355
NP_071927                                                              16    7355
NP_919415                                                              16    7355
NP_003565                                                              16    7355
NP_001124334                                                           16    7355
NP_006470                                                              16    7355
NP_006556                                                              15    9605
NP_000446                                                              15    9605
NP_000159                                                              15    9605
NP_009122                                                              15    9605
NP_009089                                                              15    9605
NP_001007554                                                           15    9605
NP_001229820                                                           15    9605
NP_001123995                                                           15    9605
NP_001229822                                                           15    9605
NP_001229821                                                           15    9605
NP_006306                                                              15    9605
NP_001093112                                                           15    9605
NP_079527                                                              15    9605
NP_065827                                                              15    9605
NP_060818                                                              15    9605
NP_055871                                                              15    9605
XP_005259675                                                           15    9605
XP_005259674                                                           15    9605
XP_005258376                                                           15    9605
XP_005258375                                                           15    9605
XP_005258374                                                           15    9605
XP_006722574                                                           15    9605
XP_006722573                                                           15    9605
XP_005258372                                                           15    9605
XP_005256104                                                           15    9605
XP_005256103                                                           15    9605
XP_005255832                                                           15    9605
XP_006716724                                                           15    9605
XP_005249761                                                           15    9605
XP_005249760                                                           15    9605
XP_006713915                                                           15    9605
XP_005272311                                                           15    9605
XP_005272310                                                           15    9605
XP_005272309                                                           15    9605
XP_005272307                                                           15    9605
>NP_001001557
          Length = 455

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   KKSKLRCS 9
           KKS+LRCS
Sbjct: 348 KKSRLRCS 355
>NP_689707
          Length = 706

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KSKLRCS 9
           K+KLRCS
Sbjct: 243 KTKLRCS 249
>NP_001137159
          Length = 681

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KSKLRCS 9
           K+KLRCS
Sbjct: 218 KTKLRCS 224
>NP_061881
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LKKSKLRCS 9
           LKKS+LR S
Sbjct: 126 LKKSRLRMS 134
>NP_004806
          Length = 1261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKKSKLRC 8
           LKK+KL C
Sbjct: 325 LKKAKLLC 332
>XP_006711111
          Length = 1197

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LKKSKLRC 8
           LKK+KL C
Sbjct: 261 LKKAKLLC 268
>NP_114113
          Length = 913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKSK  CS
Sbjct: 204 KKSKADCS 211
>NP_004729
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           L  SKLRC
Sbjct: 114 LMDSKLRC 121
>NP_775864
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LKKSKLR 7
           LK+SKLR
Sbjct: 838 LKRSKLR 844
>NP_001230166
          Length = 161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LKK+K  CS
Sbjct: 95  LKKTKETCS 103
>XP_006723951
          Length = 147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  LKKSKLRC 8
          L  SKLRC
Sbjct: 18 LMDSKLRC 25
>XP_005260860
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_005260859
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_005260858
          Length = 643

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_005260857
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_006723671
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_006723670
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_005260854
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_006723669
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>XP_006719018
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           KKSK +C+
Sbjct: 113 KKSKSKCN 120
>XP_006719016
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           KKSK +C+
Sbjct: 161 KKSKSKCN 168
>XP_006719015
          Length = 285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           KKSK +C+
Sbjct: 231 KKSKSKCN 238
>XP_005251183
          Length = 161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LKK+K  CS
Sbjct: 95  LKKTKETCS 103
>NP_071927
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KKSKLRCS 9
           KKS  +CS
Sbjct: 313 KKSNFKCS 320
>NP_919415
          Length = 249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           L  SKLRC
Sbjct: 121 LMDSKLRC 128
>NP_003565
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           L  SKLRC
Sbjct: 121 LMDSKLRC 128
>NP_001124334
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           KKSK +C+
Sbjct: 248 KKSKSKCN 255
>NP_006470
          Length = 335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           KKSK +C+
Sbjct: 231 KKSKSKCN 238
>NP_006556
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKSKLR 7
           KKSKLR
Sbjct: 208 KKSKLR 213
>NP_000446
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LKKSKLR 7
          LKK KLR
Sbjct: 80 LKKKKLR 86
>NP_000159
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKKSKLRC 8
            L  SKL+C
Sbjct: 1172 LSSSKLKC 1179
>NP_009122
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KSKLRCS 9
           KSK +CS
Sbjct: 291 KSKCKCS 297
>NP_009089
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           LKK + RC
Sbjct: 148 LKKKQARC 155
>NP_001007554
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           LKK + RC
Sbjct: 179 LKKKQARC 186
>NP_001229820
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           LKK + RC
Sbjct: 225 LKKKQARC 232
>NP_001123995
          Length = 813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           LKK + RC
Sbjct: 194 LKKKQARC 201
>NP_001229822
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           LKK + RC
Sbjct: 148 LKKKQARC 155
>NP_001229821
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LKKSKLRC 8
           LKK + RC
Sbjct: 179 LKKKQARC 186
>NP_006306
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LK+  +RCS
Sbjct: 169 LKRKWIRCS 177
>NP_001093112
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           +KKS + CS
Sbjct: 420 VKKSSIGCS 428
>NP_079527
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKSKLR 7
           KKSKLR
Sbjct: 855 KKSKLR 860
>NP_065827
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           +KS L+CS
Sbjct: 196 RKSTLQCS 203
>NP_060818
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           +KKS + CS
Sbjct: 420 VKKSSIGCS 428
>NP_055871
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LKKSKLR 7
           LKK KLR
Sbjct: 631 LKKQKLR 637
>XP_005259675
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LKKSKLR 7
          LKK KLR
Sbjct: 80 LKKKKLR 86
>XP_005259674
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LKKSKLR 7
          LKK KLR
Sbjct: 80 LKKKKLR 86
>XP_005258376
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KKSKLRCS 9
          +KS L+CS
Sbjct: 88 RKSTLQCS 95
>XP_005258375
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           +KS L+CS
Sbjct: 151 RKSTLQCS 158
>XP_005258374
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           +KS L+CS
Sbjct: 192 RKSTLQCS 199
>XP_006722574
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           +KS L+CS
Sbjct: 196 RKSTLQCS 203
>XP_006722573
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           +KS L+CS
Sbjct: 192 RKSTLQCS 199
>XP_005258372
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KKSKLRCS 9
           +KS L+CS
Sbjct: 196 RKSTLQCS 203
>XP_005256104
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           +KKS + CS
Sbjct: 420 VKKSSIGCS 428
>XP_005256103
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           +KKS + CS
Sbjct: 420 VKKSSIGCS 428
>XP_005255832
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKSKLR 7
           KKSKLR
Sbjct: 208 KKSKLR 213
>XP_006716724
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKSKLR 7
           KKSKLR
Sbjct: 711 KKSKLR 716
>XP_005249761
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKKSKLRC 8
            L  SKL+C
Sbjct: 1172 LSSSKLKC 1179
>XP_005249760
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LKKSKLRC 8
            L  SKL+C
Sbjct: 1172 LSSSKLKC 1179
>XP_006713915
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LK+  +RCS
Sbjct: 135 LKRKWIRCS 143
>XP_005272311
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LK+  +RCS
Sbjct: 135 LKRKWIRCS 143
>XP_005272310
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LK+  +RCS
Sbjct: 135 LKRKWIRCS 143
>XP_005272309
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LK+  +RCS
Sbjct: 169 LKRKWIRCS 177
>XP_005272307
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LKKSKLRCS 9
           LK+  +RCS
Sbjct: 169 LKRKWIRCS 177
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.126    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 621,479
Number of extensions: 1004
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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