Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     869
NP_005913                                                              19     869
XP_005267046                                                           19     869
XP_005267045                                                           19     869
NP_001138384                                                           17    4312
NP_001129503                                                           17    4312
NP_006386                                                              17    4312
XP_006712999                                                           17    4312
XP_005264860                                                           17    4312
XP_006712998                                                           17    4312
XP_006712997                                                           17    4312
XP_006712996                                                           17    4312
XP_006712995                                                           17    4312
XP_006712994                                                           17    4312
NP_066000                                                              16    7355
NP_001189402                                                           16    7355
NP_060736                                                              16    7355
NP_001275677                                                           16    7355
NP_071332                                                              16    7355
NP_878907                                                              16    7355
NP_001277026                                                           16    7355
NP_001139808                                                           16    7355
XP_005273981                                                           16    7355
XP_006713781                                                           16    7355
XP_005247635                                                           16    7355
XP_005247634                                                           16    7355
XP_006713750                                                           16    7355
NP_057197                                                              15    9605
NP_001259017                                                           15    9605
NP_001259016                                                           15    9605
NP_057664                                                              15    9605
NP_079514                                                              15    9605
NP_079203                                                              15    9605
NP_001011885                                                           15    9605
NP_060267                                                              15    9605
NP_005062                                                              15    9605
XP_005276813                                                           15    9605
XP_006722907                                                           15    9605
XP_006722906                                                           15    9605
XP_006722905                                                           15    9605
XP_005259650                                                           15    9605
XP_006722159                                                           15    9605
XP_006721606                                                           15    9605
XP_006721605                                                           15    9605
XP_006721604                                                           15    9605
XP_005256733                                                           15    9605
XP_006720636                                                           15    9605
XP_005248455                                                           15    9605
NP_001790                                                              15    9605
>NP_006715
          Length = 1558

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LINAYLLLT 9
           LI+AYLLLT
Sbjct: 896 LIDAYLLLT 904
>NP_005913
          Length = 1608

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LINAYLLLT 9
           LI+AYLLLT
Sbjct: 896 LIDAYLLLT 904
>XP_005267046
          Length = 1554

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LINAYLLLT 9
           LI+AYLLLT
Sbjct: 896 LIDAYLLLT 904
>XP_005267045
          Length = 1604

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LINAYLLLT 9
           LI+AYLLLT
Sbjct: 896 LIDAYLLLT 904
>NP_001138384
          Length = 623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>NP_001129503
          Length = 676

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>NP_006386
          Length = 703

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>XP_006712999
          Length = 685

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>XP_005264860
          Length = 695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>XP_006712998
          Length = 699

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>XP_006712997
          Length = 701

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>XP_006712996
          Length = 738

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>XP_006712995
          Length = 738

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>XP_006712994
          Length = 738

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+N +LLLT
Sbjct: 127 LLNKFLLLT 135
>NP_066000
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LINAYLLL 8
           L+N YL+L
Sbjct: 641 LVNIYLML 648
>NP_001189402
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           +INA L+LT
Sbjct: 184 IINASLILT 192
>NP_060736
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INAYLLLT 9
           INA+++LT
Sbjct: 327 INAFVMLT 334
>NP_001275677
          Length = 604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NAYLLL 8
           NAYLLL
Sbjct: 329 NAYLLL 334
>NP_071332
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INAYLLLT 9
           +N YLL+T
Sbjct: 136 LNRYLLIT 143
>NP_878907
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NAYLLL 8
           NAYLLL
Sbjct: 329 NAYLLL 334
>NP_001277026
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LINAYLLL 8
          L+ AYLLL
Sbjct: 48 LLQAYLLL 55
>NP_001139808
          Length = 223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LINAYLLL 8
           L+ AYLLL
Sbjct: 129 LLQAYLLL 136
>XP_005273981
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NAYLLL 8
           NAYLLL
Sbjct: 329 NAYLLL 334
>XP_006713781
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LINAYLLL 8
           L+N YL+L
Sbjct: 641 LVNIYLML 648
>XP_005247635
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INAYLLLT 9
           INA+++LT
Sbjct: 327 INAFVMLT 334
>XP_005247634
          Length = 380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INAYLLLT 9
           INA+++LT
Sbjct: 327 INAFVMLT 334
>XP_006713750
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INAYLLLT 9
           INA+++LT
Sbjct: 327 INAFVMLT 334
>NP_057197
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+ AY+LLT
Sbjct: 625 LLLAYVLLT 633
>NP_001259017
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NAYLLLT 9
          NA++LLT
Sbjct: 56 NAFILLT 62
>NP_001259016
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NAYLLLT 9
          NA++LLT
Sbjct: 56 NAFILLT 62
>NP_057664
          Length = 1184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NAYLLLT 9
           N Y+LLT
Sbjct: 408 NTYMLLT 414
>NP_079514
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAYLLLT 9
           NA++LLT
Sbjct: 179 NAFMLLT 185
>NP_079203
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LINAYL 6
           L+NAYL
Sbjct: 742 LVNAYL 747
>NP_001011885
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAYLLLT 9
           NA++LLT
Sbjct: 179 NAFMLLT 185
>NP_060267
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAYLLLT 9
           NA++LLT
Sbjct: 221 NAFMLLT 227
>NP_005062
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NAYLLLT 9
          NA++LLT
Sbjct: 56 NAFILLT 62
>XP_005276813
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  INAYLLLT 9
          I AY+L+T
Sbjct: 57 IKAYMLMT 64
>XP_006722907
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NAYLLLT 9
          NA++LLT
Sbjct: 56 NAFILLT 62
>XP_006722906
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NAYLLLT 9
          NA++LLT
Sbjct: 56 NAFILLT 62
>XP_006722905
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NAYLLLT 9
          NA++LLT
Sbjct: 56 NAFILLT 62
>XP_005259650
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NAYLLLT 9
          NA++LLT
Sbjct: 73 NAFMLLT 79
>XP_006722159
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LINAYL 6
           L+NAYL
Sbjct: 739 LVNAYL 744
>XP_006721606
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+ AY+LLT
Sbjct: 625 LLLAYVLLT 633
>XP_006721605
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+ AY+LLT
Sbjct: 625 LLLAYVLLT 633
>XP_006721604
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+ AY+LLT
Sbjct: 625 LLLAYVLLT 633
>XP_005256733
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LINAYLLLT 9
           L+ AY+LLT
Sbjct: 624 LLLAYVLLT 632
>XP_006720636
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAYLLLT 9
           NA++LLT
Sbjct: 179 NAFMLLT 185
>XP_005248455
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  INAYLLLT 9
          I AY+L+T
Sbjct: 57 IKAYMLMT 64
>NP_001790
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INAYLLLT 9
           I AY+L+T
Sbjct: 114 IKAYMLMT 121
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.151    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 417,515
Number of extensions: 491
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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