Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              20     390
NP_001276866                                                           18    1135
NP_004439                                                              18    1135
NP_001276865                                                           18    1135
NP_001005862                                                           18    1135
NP_001269346                                                           18    1135
NP_001035915                                                           18    1135
NP_689564                                                              18    1135
NP_001257577                                                           18    1135
XP_005257197                                                           18    1135
XP_006721828                                                           18    1135
XP_006721514                                                           18    1135
XP_006721513                                                           18    1135
XP_005256514                                                           18    1135
NP_001036064                                                           17    3301
NP_004963                                                              17    3301
NP_005226                                                              17    3301
NP_775267                                                              17    3301
NP_775268                                                              17    3301
NP_001128653                                                           17    3301
NP_001011547                                                           17    3301
NP_775266                                                              17    3301
NP_004094                                                              17    3301
XP_005251512                                                           17    3301
XP_005273505                                                           17    3301
XP_005273504                                                           17    3301
XP_005246434                                                           17    3301
XP_005246433                                                           17    3301
XP_005246432                                                           17    3301
XP_006712427                                                           17    3301
NP_001003803                                                           17    4312
XP_005267596                                                           17    4312
NP_001003805                                                           17    4312
NP_056499                                                              17    4312
NP_112235                                                              16    5631
NP_008864                                                              16    5631
NP_001192209                                                           16    5631
NP_001020330                                                           16    5631
NP_001020329                                                           16    5631
NP_004346                                                              16    5631
XP_005259057                                                           16    5631
XP_005259056                                                           16    5631
XP_006723307                                                           16    5631
XP_005259055                                                           16    5631
XP_006714874                                                           16    5631
NP_059128                                                              16    5631
NP_060124                                                              16    7355
NP_689892                                                              16    7355
NP_001180236                                                           16    7355
NP_001238831                                                           15    9605
NP_003976                                                              15    9605
NP_002218                                                              15    9605
NP_940933                                                              15    9605
XP_006722513                                                           15    9605
XP_006722512                                                           15    9605
XP_005266752                                                           15    9605
XP_005266751                                                           15    9605
XP_006722511                                                           15    9605
XP_006722510                                                           15    9605
XP_005266750                                                           15    9605
XP_005266749                                                           15    9605
XP_005266748                                                           15    9605
XP_005266747                                                           15    9605
XP_005270898                                                           15    9605
XP_006710687                                                           15    9605
>NP_005219
          Length = 1210

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           LI QLMPFG
Sbjct: 788 LITQLMPFG 796
>NP_001276866
          Length = 1055

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+ QLMP+G
Sbjct: 796 LVTQLMPYG 804
>NP_004439
          Length = 1255

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+ QLMP+G
Sbjct: 796 LVTQLMPYG 804
>NP_001276865
          Length = 1240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+ QLMP+G
Sbjct: 781 LVTQLMPYG 789
>NP_001005862
          Length = 1225

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+ QLMP+G
Sbjct: 766 LVTQLMPYG 774
>NP_001269346
          Length = 566

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+LMP G
Sbjct: 289 LVMELMPIG 297
>NP_001035915
          Length = 596

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+LMP G
Sbjct: 356 LVMELMPIG 364
>NP_689564
          Length = 612

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+LMP G
Sbjct: 372 LVMELMPIG 380
>NP_001257577
          Length = 569

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+LMP G
Sbjct: 329 LVMELMPIG 337
>XP_005257197
          Length = 1225

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+ QLMP+G
Sbjct: 766 LVTQLMPYG 774
>XP_006721828
          Length = 1336

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+ QLMP+G
Sbjct: 877 LVTQLMPYG 885
>XP_006721514
          Length = 596

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+LMP G
Sbjct: 356 LVMELMPIG 364
>XP_006721513
          Length = 598

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+LMP G
Sbjct: 321 LVMELMPIG 329
>XP_005256514
          Length = 633

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+LMP G
Sbjct: 356 LVMELMPIG 364
>NP_001036064
          Length = 1292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+ QLMP G
Sbjct: 794 LVTQLMPHG 802
>NP_004963
          Length = 1132

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           LIM+ +P+G
Sbjct: 927 LIMEYLPYG 935
>NP_005226
          Length = 1308

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+ QLMP G
Sbjct: 794 LVTQLMPHG 802
>NP_775267
          Length = 967

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           +IM+L P+G
Sbjct: 500 IIMELYPYG 508
>NP_775268
          Length = 1009

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           +IM+L P+G
Sbjct: 500 IIMELYPYG 508
>NP_001128653
          Length = 706

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+M LMP G
Sbjct: 398 LVMALMPVG 406
>NP_001011547
          Length = 681

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+M LMP G
Sbjct: 373 LVMALMPVG 381
>NP_775266
          Length = 1009

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           +IM+L P+G
Sbjct: 500 IIMELYPYG 508
>NP_004094
          Length = 1009

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           +IM+L P+G
Sbjct: 500 IIMELYPYG 508
>XP_005251512
          Length = 1132

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           LIM+ +P+G
Sbjct: 927 LIMEYLPYG 935
>XP_005273505
          Length = 997

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           +IM+L P+G
Sbjct: 500 IIMELYPYG 508
>XP_005273504
          Length = 1009

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           +IM+L P+G
Sbjct: 500 IIMELYPYG 508
>XP_005246434
          Length = 1282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+ QLMP G
Sbjct: 784 LVTQLMPHG 792
>XP_005246433
          Length = 1298

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+ QLMP G
Sbjct: 784 LVTQLMPHG 792
>XP_005246432
          Length = 1307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+ QLMP G
Sbjct: 809 LVTQLMPHG 817
>XP_006712427
          Length = 1323

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+ QLMP G
Sbjct: 809 LVTQLMPHG 817
>NP_001003803
          Length = 215

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLMPFG 9
          Q+MPFG
Sbjct: 15 QMMPFG 20
>XP_005267596
          Length = 178

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLMPFG 9
          Q+MPFG
Sbjct: 15 QMMPFG 20
>NP_001003805
          Length = 127

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLMPFG 9
          Q+MPFG
Sbjct: 15 QMMPFG 20
>NP_056499
          Length = 136

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLMPFG 9
          Q+MPFG
Sbjct: 15 QMMPFG 20
>NP_112235
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIMQLMP 7
           LIMQL+P
Sbjct: 448 LIMQLIP 454
>NP_008864
          Length = 718

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LIMQLMPFG 9
           L+M+L+P G
Sbjct: 354 LVMKLVPVG 362
>NP_001192209
          Length = 192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LIMQLMP 7
          L++QLMP
Sbjct: 41 LVLQLMP 47
>NP_001020330
          Length = 296

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+MQ +P G
Sbjct: 113 LLMQALPMG 121
>NP_001020329
          Length = 160

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+MQ +P G
Sbjct: 113 LLMQALPMG 121
>NP_004346
          Length = 232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+MQ +P G
Sbjct: 113 LLMQALPMG 121
>XP_005259057
          Length = 416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIMQLMP 7
           LIMQL+P
Sbjct: 140 LIMQLIP 146
>XP_005259056
          Length = 416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIMQLMP 7
           LIMQL+P
Sbjct: 140 LIMQLIP 146
>XP_006723307
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIMQLMP 7
           LIMQL+P
Sbjct: 155 LIMQLIP 161
>XP_005259055
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIMQLMP 7
           LIMQL+P
Sbjct: 155 LIMQLIP 161
>XP_006714874
          Length = 334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           L+MQ +P G
Sbjct: 190 LLMQALPMG 198
>NP_059128
          Length = 416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LIMQLMP 7
           LIMQL+P
Sbjct: 140 LIMQLIP 146
>NP_060124
          Length = 1589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IMQLMPF 8
            I+QL+PF
Sbjct: 1210 ILQLIPF 1216
>NP_689892
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IMQLMPFG 9
           I+QL+P G
Sbjct: 228 IVQLLPLG 235
>NP_001180236
          Length = 1589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IMQLMPF 8
            I+QL+PF
Sbjct: 1210 ILQLIPF 1216
>NP_001238831
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           ++M+L P G
Sbjct: 194 MVMELAPLG 202
>NP_003976
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           ++M+L P G
Sbjct: 194 MVMELAPLG 202
>NP_002218
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           LIM+ +P G
Sbjct: 954 LIMEFLPSG 962
>NP_940933
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_006722513
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 267 ILQLFPF 273
>XP_006722512
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 321 ILQLFPF 327
>XP_005266752
          Length = 1018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266751
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_006722511
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_006722510
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266750
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266749
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266748
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266747
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IMQLMPF 8
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005270898
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           LIM+ +P G
Sbjct: 954 LIMEFLPSG 962
>XP_006710687
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LIMQLMPFG 9
           LIM+ +P G
Sbjct: 954 LIMEFLPSG 962
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.160    0.495 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 522,459
Number of extensions: 648
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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