Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              18    1482
NP_005913                                                              18    1482
XP_005267046                                                           18    1482
XP_005267045                                                           18    1482
NP_001095896                                                           17    4312
NP_001122090                                                           17    4312
XP_005263921                                                           17    4312
XP_005263920                                                           17    4312
XP_005263919                                                           17    4312
NP_001273596                                                           16    7355
NP_001273595                                                           16    7355
NP_001273594                                                           16    7355
NP_001129406                                                           16    7355
NP_001129407                                                           16    7355
NP_006466                                                              16    7355
NP_001129408                                                           16    7355
XP_005266289                                                           16    7355
XP_005266288                                                           16    7355
NP_001182181                                                           15    9605
NP_620581                                                              15    9605
NP_620583                                                              15    9605
NP_620582                                                              15    9605
NP_009041                                                              15    9605
NP_001182183                                                           15    9605
NP_001182178                                                           15    9605
NP_005329                                                              15    9605
NP_976241                                                              15    9605
NP_778243                                                              15    9605
NP_001182179                                                           15    9605
NP_998754                                                              15    9605
NP_001182177                                                           15    9605
NP_001230127                                                           15    9605
NP_004446                                                              15    9605
XP_005261547                                                           15    9605
XP_005268084                                                           15    9605
XP_006719746                                                           15    9605
XP_005253685                                                           15    9605
XP_005253684                                                           15    9605
XP_006716855                                                           15    9605
XP_006716854                                                           15    9605
XP_005250362                                                           15    9605
XP_005250361                                                           15    9605
XP_006715061                                                           15    9605
XP_005246837                                                           15    9605
XP_005246836                                                           15    9605
XP_006712758                                                           15    9605
XP_005246834                                                           15    9605
XP_006710511                                                           15    9605
XP_006710510                                                           15    9605
XP_005245836                                                           15    9605
NP_003950                                                              15    9605
NP_001004744                                                           15    9605
NP_056185                                                              15    9605
>NP_006715
          Length = 1558

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L KLILRLH
Sbjct: 539 LRKLILRLH 547
>NP_005913
          Length = 1608

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L KLILRLH
Sbjct: 539 LRKLILRLH 547
>XP_005267046
          Length = 1554

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L KLILRLH
Sbjct: 539 LRKLILRLH 547
>XP_005267045
          Length = 1604

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L KLILRLH
Sbjct: 539 LRKLILRLH 547
>NP_001095896
          Length = 1140

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           IKL+ RLH
Sbjct: 917 IKLLYRLH 924
>NP_001122090
          Length = 161

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+K IL+LH
Sbjct: 138 LVKRILQLH 146
>XP_005263921
          Length = 1147

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           IKL+ RLH
Sbjct: 924 IKLLYRLH 931
>XP_005263920
          Length = 1155

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           IKL+ RLH
Sbjct: 932 IKLLYRLH 939
>XP_005263919
          Length = 1162

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           IKL+ RLH
Sbjct: 939 IKLLYRLH 946
>NP_001273596
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>NP_001273595
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>NP_001273594
          Length = 809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>NP_001129406
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>NP_001129407
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>NP_006466
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>NP_001129408
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>XP_005266289
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>XP_005266288
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LIKLILRLH 9
           L+KLIL+ H
Sbjct: 424 LLKLILQNH 432
>NP_001182181
          Length = 284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 254 LLKLPLRCH 262
>NP_620581
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IKLILRL 8
           +KLILRL
Sbjct: 232 LKLILRL 238
>NP_620583
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IKLILRL 8
           +KLILRL
Sbjct: 232 LKLILRL 238
>NP_620582
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IKLILRL 8
           +KLILRL
Sbjct: 232 LKLILRL 238
>NP_009041
          Length = 2627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L KL+ RLH
Sbjct: 441 LKKLVQRLH 449
>NP_001182183
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 258 LLKLPLRCH 266
>NP_001182178
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 312 LLKLPLRCH 320
>NP_005329
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 240 VKLLFKLH 247
>NP_976241
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLILRLH 9
           KL++R+H
Sbjct: 322 KLVIRVH 328
>NP_778243
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 312 LLKLPLRCH 320
>NP_001182179
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 272 LLKLPLRCH 280
>NP_998754
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLILRLH 9
           KL++R+H
Sbjct: 270 KLVIRVH 276
>NP_001182177
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 326 LLKLPLRCH 334
>NP_001230127
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 240 VKLLFKLH 247
>NP_004446
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LILRLH 9
           L+LRLH
Sbjct: 160 LVLRLH 165
>XP_005261547
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LIKLILR 7
          L+KL+LR
Sbjct: 35 LVKLVLR 41
>XP_005268084
          Length = 2627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L KL+ RLH
Sbjct: 441 LKKLVQRLH 449
>XP_006719746
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 219 VKLLFKLH 226
>XP_005253685
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 219 VKLLFKLH 226
>XP_005253684
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 231 VKLLFKLH 238
>XP_006716855
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 224 LLKLPLRCH 232
>XP_006716854
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LIKLILRLH 9
           L+KL LR H
Sbjct: 312 LLKLPLRCH 320
>XP_005250362
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 206 VKLLFKLH 213
>XP_005250361
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 211 VKLLFKLH 218
>XP_006715061
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IKLILRL 8
           +KLILRL
Sbjct: 155 LKLILRL 161
>XP_005246837
          Length = 1277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLILRLH 9
           KL++R+H
Sbjct: 297 KLVIRVH 303
>XP_005246836
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLILRLH 9
           KL++R+H
Sbjct: 322 KLVIRVH 328
>XP_006712758
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLILRLH 9
           KL++R+H
Sbjct: 322 KLVIRVH 328
>XP_005246834
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLILRLH 9
           KL++R+H
Sbjct: 322 KLVIRVH 328
>XP_006710511
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LILRLH 9
           L+LRLH
Sbjct: 160 LVLRLH 165
>XP_006710510
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LILRLH 9
           L+LRLH
Sbjct: 160 LVLRLH 165
>XP_005245836
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LILRLH 9
           L+LRLH
Sbjct: 160 LVLRLH 165
>NP_003950
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKLILRLH 9
           +KL+ +LH
Sbjct: 231 VKLLFKLH 238
>NP_001004744
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LIKLILRLH 9
          LIK+  RLH
Sbjct: 48 LIKIDTRLH 56
>NP_056185
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LIKLILR 7
          L+KL+LR
Sbjct: 76 LVKLVLR 82
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.352    0.169    0.467 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,754
Number of extensions: 895
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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