Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              18    1135
XP_005250103                                                           18    1135
XP_005250102                                                           18    1135
NP_000866                                                              16    5631
NP_940912                                                              16    5631
NP_203751                                                              16    5631
NP_001243497                                                           16    5631
NP_003612                                                              16    5631
NP_001243498                                                           16    5631
XP_005254953                                                           16    5631
XP_006720550                                                           16    5631
XP_006720549                                                           16    5631
XP_006718416                                                           16    5631
XP_006718415                                                           16    5631
XP_006718414                                                           16    5631
XP_006718413                                                           16    5631
XP_005253234                                                           16    5631
XP_006718412                                                           16    5631
XP_005253233                                                           16    5631
XP_005253232                                                           16    5631
XP_005253231                                                           16    5631
XP_006714457                                                           16    5631
XP_006714456                                                           16    5631
XP_005263376                                                           16    5631
NP_940906                                                              16    5631
NP_579872                                                              16    7355
NP_001693                                                              16    7355
XP_005251072                                                           16    7355
XP_006710853                                                           16    7355
XP_006710852                                                           16    7355
XP_006710851                                                           16    7355
XP_006710850                                                           16    7355
XP_006710849                                                           16    7355
XP_005271124                                                           16    7355
XP_006710848                                                           16    7355
XP_006710847                                                           16    7355
XP_006710846                                                           16    7355
NP_001139669                                                           16    7355
NP_954981                                                              16    7355
NP_001694                                                              16    7355
NP_005912                                                              15    9605
NP_009121                                                              15    9605
NP_001128248                                                           15    9605
NP_001128247                                                           15    9605
NP_663782                                                              15    9605
NP_001096029                                                           15    9605
NP_085076                                                              15    9605
NP_071940                                                              15    9605
NP_001005417                                                           15    9605
NP_065907                                                              15    9605
NP_001118                                                              15    9605
NP_003771                                                              15    9605
XP_005268066                                                           15    9605
XP_005269174                                                           15    9605
XP_006718728                                                           15    9605
XP_005274241                                                           15    9605
XP_005274240                                                           15    9605
XP_005274239                                                           15    9605
XP_005269527                                                           15    9605
XP_005269526                                                           15    9605
XP_005273720                                                           15    9605
XP_005273718                                                           15    9605
XP_005248577                                                           15    9605
XP_005248576                                                           15    9605
XP_006711080                                                           15    9605
XP_005271361                                                           15    9605
NP_001159491                                                           15    9605
NP_073733                                                              15    9605
NP_001096030                                                           15    9605
NP_115872                                                              15    9605
>NP_004324
          Length = 766

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           L LLFVSKF
Sbjct: 286 LDLLFVSKF 294
>XP_005250103
          Length = 758

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           L LLFVSKF
Sbjct: 286 LDLLFVSKF 294
>XP_005250102
          Length = 767

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           L LLFVSKF
Sbjct: 286 LDLLFVSKF 294
>NP_000866
          Length = 1367

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LHLLFVSK 8
          LH+L +SK
Sbjct: 59 LHILLISK 66
>NP_940912
          Length = 1313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  HLLFVSKF 9
          HL F+S F
Sbjct: 77 HLAFISNF 84
>NP_203751
          Length = 1143

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           LHLLFV
Sbjct: 377 LHLLFV 382
>NP_001243497
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 575 IHVLHVNKF 583
>NP_003612
          Length = 876

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 687 IHVLHVNKF 695
>NP_001243498
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 544 IHVLHVNKF 552
>XP_005254953
          Length = 1366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LHLLFVSK 8
          LH+L +SK
Sbjct: 59 LHILLISK 66
>XP_006720550
          Length = 1373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LHLLFVSK 8
          LH+L +SK
Sbjct: 66 LHILLISK 73
>XP_006720549
          Length = 1374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LHLLFVSK 8
          LH+L +SK
Sbjct: 66 LHILLISK 73
>XP_006718416
          Length = 784

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 555 IHVLHVNKF 563
>XP_006718415
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 610 IHVLHVNKF 618
>XP_006718414
          Length = 850

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 621 IHVLHVNKF 629
>XP_006718413
          Length = 887

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 698 IHVLHVNKF 706
>XP_005253234
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 687 IHVLHVNKF 695
>XP_006718412
          Length = 927

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 698 IHVLHVNKF 706
>XP_005253233
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 748 IHVLHVNKF 756
>XP_005253232
          Length = 948

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 759 IHVLHVNKF 767
>XP_005253231
          Length = 977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LHLLFVSKF 9
           +H+L V+KF
Sbjct: 748 IHVLHVNKF 756
>XP_006714457
          Length = 809

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LHLLFV 6
          LHLLFV
Sbjct: 43 LHLLFV 48
>XP_006714456
          Length = 1143

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           LHLLFV
Sbjct: 377 LHLLFV 382
>XP_005263376
          Length = 1143

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           LHLLFV
Sbjct: 377 LHLLFV 382
>NP_940906
          Length = 377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLFVSKF 9
           LLF+SKF
Sbjct: 95  LLFLSKF 101
>NP_579872
          Length = 59

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LHLLFVSK 8
          LHLLF+ +
Sbjct: 29 LHLLFLKR 36
>NP_001693
          Length = 1584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    LHLLFVSKF 9
            LH  F+S F
Sbjct: 1018 LHFFFLSSF 1026
>XP_005251072
          Length = 1586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    LHLLFVSKF 9
            LH  F+S F
Sbjct: 1015 LHFFFLSSF 1023
>XP_006710853
          Length = 1478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LHLLFVSKF 9
           LH  F+S F
Sbjct: 948 LHFFFLSSF 956
>XP_006710852
          Length = 1497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LHLLFVSKF 9
           LH  F+S F
Sbjct: 948 LHFFFLSSF 956
>XP_006710851
          Length = 1511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LHLLFVSKF 9
           LH  F+S F
Sbjct: 948 LHFFFLSSF 956
>XP_006710850
          Length = 1530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LHLLFVSKF 9
           LH  F+S F
Sbjct: 948 LHFFFLSSF 956
>XP_006710849
          Length = 1530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LHLLFVSKF 9
           LH  F+S F
Sbjct: 948 LHFFFLSSF 956
>XP_005271124
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    LHLLFVSKF 9
            LH  F+S F
Sbjct: 1003 LHFFFLSSF 1011
>XP_006710848
          Length = 1552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    LHLLFVSKF 9
            LH  F+S F
Sbjct: 1003 LHFFFLSSF 1011
>XP_006710847
          Length = 1566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    LHLLFVSKF 9
            LH  F+S F
Sbjct: 1003 LHFFFLSSF 1011
>XP_006710846
          Length = 1584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    LHLLFVSKF 9
            LH  F+S F
Sbjct: 1003 LHFFFLSSF 1011
>NP_001139669
          Length = 7081

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LHLLFVSK 8
           LHL+ VSK
Sbjct: 541 LHLISVSK 548
>NP_954981
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           H+LF+SK
Sbjct: 135 HVLFLSK 141
>NP_001694
          Length = 1585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    LHLLFVSKF 9
            LH  F+S F
Sbjct: 1003 LHFFFLSSF 1011
>NP_005912
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           +HLLFV
Sbjct: 356 IHLLFV 361
>NP_009121
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHLLFVSK 8
           LH LF+S+
Sbjct: 562 LHALFMSR 569
>NP_001128248
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>NP_001128247
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>NP_663782
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           LH+LFV
Sbjct: 824 LHILFV 829
>NP_001096029
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LHLLFVSKF 9
          L L+F++KF
Sbjct: 69 LSLIFLAKF 77
>NP_085076
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  HLLFVSKF 9
          HL F S+F
Sbjct: 67 HLAFFSRF 74
>NP_071940
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LHLLFV 6
          LH+LFV
Sbjct: 11 LHILFV 16
>NP_001005417
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  HLLFVSKF 9
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>NP_065907
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    HLLFVSK 8
            HLL+VS+
Sbjct: 1071 HLLYVSE 1077
>NP_001118
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           LH+LFV
Sbjct: 831 LHILFV 836
>NP_003771
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  HLLFVSKF 9
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>XP_005268066
          Length = 1172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           LH+LFV
Sbjct: 245 LHILFV 250
>XP_005269174
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LHLLFVSKF 9
           LHL F +KF
Sbjct: 220 LHLGFSTKF 228
>XP_006718728
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_005274241
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_005274240
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_005274239
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_005269527
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHLLFVSK 8
           LH LF+S+
Sbjct: 515 LHALFMSR 522
>XP_005269526
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LHLLFVSK 8
           LH LF+S+
Sbjct: 562 LHALFMSR 569
>XP_005273720
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LHLLFVSKF 9
          L L+F++KF
Sbjct: 69 LSLIFLAKF 77
>XP_005273718
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LHLLFVSKF 9
          L L+F++KF
Sbjct: 69 LSLIFLAKF 77
>XP_005248577
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           +HLLFV
Sbjct: 193 IHLLFV 198
>XP_005248576
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           +HLLFV
Sbjct: 219 IHLLFV 224
>XP_006711080
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  HLLFVSKF 9
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>XP_005271361
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  HLLFVSKF 9
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>NP_001159491
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LHLLFV 6
           LH+LFV
Sbjct: 804 LHILFV 809
>NP_073733
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HLLFVSK 8
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>NP_001096030
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LHLLFVSKF 9
          L L+F++KF
Sbjct: 69 LSLIFLAKF 77
>NP_115872
          Length = 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LHLLFVSKF 9
          L L+F++KF
Sbjct: 69 LSLIFLAKF 77
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.351    0.159    0.480 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 471,444
Number of extensions: 732
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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